Required for pre-mRNA splicing and for exon-junction complex (EJC) assembly, Hinders EIF4A3 from non-specifically binding RNA and escorts it to the splicing machinery to promote EJC assembly on mature mRNAs, Through its role in EJC assembly, required for nonsense-mediated mRNA decay.
应用类型
WB
免疫原
Recombinant fusion protein containing a sequence corresponding to amino acids 639-908 of human CWC22 (NP_065994.1).
