The protein encoded by this gene is a post-proline cleaving aminopeptidase expressed in quiescent lymphocytes. The resting lymphocytes are maintained through suppression of apoptosis, a state which is disrupted by inhibition of this novel serine protease. The enzyme has strong sequence homology with prolylcarboxypeptidase and is active at both acidic and neutral pH.
应用类型
IF,WB
免疫原
Recombinant fusion protein containing a sequence corresponding to amino acids 190-410 of human DPP7 (NP_037511.2).