Metallocarboxypeptidase that mediates deglutamylation of target proteins, Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins, Also removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK, Acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point glutamate, a process catalyzed by AGBL5/CCP5.
应用类型
WB
免疫原
Recombinant fusion protein containing a sequence corresponding to amino acids 320-520 of human AGTPBP1 (NP_056054.2).