Plays a role in Fanconi anemia-associated DNA damage response network, Regulates FANCD2 monoubiquitination and the stability of the FA core complex, Induces chromosomal instability as well as hypersensitivity to DNA cross-linking agents, when repressed.
应用类型
WB
免疫原
Recombinant fusion protein containing a sequence corresponding to amino acids 652-881 of human C17orf70 (NP_079437.5).
