Down-regulates ESR1 protein levels through the ubiquitination-proteasome pathway, regardless of the presence of 17 beta-estradiol, Also involved in 17 beta-estradiol-induced ESR1 degradation, Controls PGR protein levels through a similar mechanism.
应用类型
WB
免疫原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human CUEDC2 (NP_076945.2).
