This gene encodes a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and is thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Alternative splicing results in multiple variants.
应用类型
WB
免疫原
Recombinant fusion protein containing a sequence corresponding to amino acids 81-247 of human Mast Cell Chymase (Mast Cell Chymase (CMA1) ) (NP_001827.1).
