Guanine nucleotide exchange factor (GEF) regulating clathrin-mediated endocytosis through RAB35 activation, Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB35 into its active GTP-bound form, Regulates clathrin-mediated endocytosis of synaptic vesicles and mediates exit from early endosomes.
应用类型
WB
免疫原
Recombinant fusion protein containing a sequence corresponding to amino acids 270-527 of human DENND1A (NP_079096.2).
