- 中文名称
Rabbit polyclonal to CSNK2A1
- 英文名字
- Rabbit polyclonal to CSNK2A1
- 供应商
- Nordic BioSite
- 产品货号
- NDC-ASJ-683A71
- 产品报价
- ￥询价/100ul
- 产品说明书
- 点击查看
- 购买方式
- 90%产品中国有现货库存。银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系400-6800-868
- 产品新闻
- 背景资料
- Catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine, Regulates numerous cellular processes, such as cell cycle progression, apoptosis and transcription, as well as viral infection, May act as a regulatory node which integrates and coordinates numerous signals leading to an appropriate cellular response, During mitosis, functions as a component of the p53/TP53-dependent spindle assembly checkpoint (SAC) that maintains cyclin-B-CDK1 activity and G2 arrest in response to spindle damage, Also required for p53/TP53-mediated apoptosis, phosphorylating 'Ser-392' of p53/TP53 following UV irradiation, Can also negatively regulate apoptosis, Phosphorylates the caspases CASP9 and CASP2 and the apoptotic regulator NOL3, Phosphorylation protects CASP9 from cleavage and activation by CASP8, and inhibits the dimerization of CASP2 and activation of CASP8, Regulates transcription by direct phosphorylation of RNA polymerases I, II, III and IV, Also phosphorylates and regulates numerous transcription factors including NF-kappa-B, STAT1, CREB1, IRF1, IRF2, ATF1, SRF, MAX, JUN, FOS, MYC and MYB, Phosphorylates Hsp90 and its co-chaperones FKBP4 and CDC37, which is essential for chaperone function, Regulates Wnt signaling by phosphorylating CTNNB1 and the transcription factor LEF1, Acts as an ectokinase that phosphorylates several extracellular proteins, During viral infection, phosphorylates various proteins involved in the viral life cycles of EBV, HSV, HBV, HCV, HIV, CMV and HPV, Phosphorylates PML at 'Ser-565' and primes it for ubiquitin-mediated degradation, Plays an important role in the circadian clock function by phosphorylating ARNTL/BMAL1 at 'Ser-90' which is pivotal for its interaction with CLOCK and which controls CLOCK nuclear entry.
- 应用类型
- WB,IHC
- 免疫原
- Recombinant protein of human CSNK2A1
- 来源宿主
- rabbit
- 反应性
- human,mouse,rat
- 保存建议
- Store at -20℃. Avoid freeze / thaw cycles.
- 其他
- Nordic BioSite(北欧生物) 总部位于瑞典，成立于1997年，旨在分销研究和诊断领域的高质量和创新产品。 Nordic BioSite 被公认为整个北欧生物医学研究和诊断产品领域的领导者。他们拥有超过570万种的产品组合，代理了遍布欧洲和美国的顶级生物试剂制造商，是欧洲知名的一站式生物试剂代理商。除了作为分销商之外，Nordic BioSite 还拥有不断增长的自产产品线——BioSite mAb、BioSite ELISA、BioSite Flow、Optibodies和 BioSite Protein, 目前艾美捷代理的是Nordic BioSite自产产品线(共26W+产品)。Nordic BioSite的产品类型主要是抗体，蛋白和试剂盒，产品适用范围涵盖15个不同的物种(人，牛，犬，鲶鱼，鸡，海豚，马，猫，豚鼠，小鼠，绵羊，兔子，大鼠，猪和火鸡)，可为您提供一站式的生命科学研究解决方案~
- 注意
-
该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
-
