Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters, Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation, Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells
应用类型
WB,IHC,IP
免疫原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human CREB1 (NP_604391.1).