This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy. [provided by RefSeq, Dec 2008]
应用类型
该小鼠抗EPCAM单克隆抗体产品的应用类型详情查看产品说明书。
免疫原
Purified recombinant fragment of human EPCAM (AA: extra(116-265)) expressed in E. Coli.
