Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene.
应用类型
该Mouse Monoclonal Antibody to NEFH产品的应用类型详情查看产品说明书。
免疫原
Purified recombinant fragment of human NEFH (AA: 2-251) expressed in E. Coli.
来源宿主
该Mouse Monoclonal Antibody to MPS1产品的来源宿主详情查看产品说明书。
