Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1(CAF-1) to promote replication-dependent chromatin assembly and with HIRA to promote replication-independent chromatin assembly. Required for the formation of senescence-associated heterochromatin foci(SAHF) and efficient senescence-associated cell cycle exit.
应用类型
ELISA,IHC,IP,WB
免疫原
ASF1 anti-silencing function 1 homolog A(S. cerevisiae)
