CDC2, Cell Division Cycle 2, is also known as CDK1(Cyclin-dependent Kinase 1). CDC2 is a catalytic subunit of a protein kinase complex, called the M-phase promoting factor, that induces entry into mitosis and is universal among eukaryotes. In HeLa cells CDC2 is the most abundant phosphotyrosine-containing protein and its phosphotyrosine content is subject to cell cycle regulation. CDC2 gene is located on chromosome 10.
应用类型
WB
免疫原
A synthetic peptide corresponding to a sequence at the C-terminus of human CDK1(279-297aa KMALNHPYFNDLDNQIKKM), different from the relative rat and mouse sequences by two amino acids.
