Ang K1-3 is a single, non-glycosylated polypeptide chain containing 259 amino acids. It represents a proteolytic fragment of plasminogen containing the first three kringle structures. Ang K1-3 reduces endothelial cell proliferation and acts as a potent inhibitor of angiogenesis and tumor growth. It displays increased inhibitory activity(ED50 = 70nM) relative to kringles 1-4(ED50 = 135nM).
应用类型
ELISA,IHC,WB
免疫原
E. coli-derived human Angiostatin K1-3 recombinant protein(Position: C103-C352).