Mouse IgG monoclonal antibody for CDK6, cyclin-dependent kinase 6 (CDK6) detection. Tested with WB, ICC in Human;mouse;rat. No cross reactivity with other proteins.
The cyclin-dependent protein kinases(CDKs) regulate major cell cycle transitions in eukaryotic cells. Cyclin-dependent kinase-6(CDK6) is the earliest inducible member of the CDK family in human T lymphocytes, involved in growth factor stimulation and cell cycle progression. Germline mutations in CDK6 do not make a significant contribution to melanoma predisposition. CDK6 gene is mapped at 7q21-q22.