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ELISA试剂盒
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中文名称

B型脑钠肽 EIA试剂盒

英文名字
BNP Fragment EIA Kit
供应商
Biomedica Immunoassays
产品货号
BI-20852W
产品报价
¥12x8tests
产品说明书
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购买方式
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产品新闻
背景资料
The natriuretic peptides are members of a family of structurally similar but genetically distinct peptide hormones, consisting of atrial-, brain-, and C-type (ANP, BNP, and CNP, respectively). ANP and BNP preferentially bind to a membrane-bound guanylyl cyclase (GC) receptor called GC-A or NPR1, whereas CNP is the physiological ligand for GC-B (NPR2). The natriuretic peptides play an important role in the regulation of cardiovascular and renal homeostasis and in the regulation of fatty acid metabolism and body weight.

BNP is mainly expressed by ventricular myocardium in response to volume overload and increased filling pressure. BNP has a cleavable signal sequence. Mature BNP consists of 108 amino acids (proBNP or BNP-108), and undergoes cleavage resulting in physiologically active BNP-32 and additional C-terminal fragments (cf. http://www.uniprot.org/uniprot/P16860#PRO_0000001532), along with a physiologically inactive N-terminal peptide comprising amino acids 1-76 (NT-proBNP), which is further degraded proteolytically.
产品描述
Method Competitive enzyme immunoassay (EIA), HRP/TMB, 12×8-well detachable strips Sample type Serum, EDTA plasma, heparın plasma, citrate plasma Product volume 30 µl / well Assay time Overnight (18 – 25 h) / 20 min Sensitivity 171 pmol/l (=1449 pg/ml) Standard range 0 – 6,400 pmol/l (0 – 54,237 pg/ml) Conversion factor 1 pmol/l = 8.475 pg/ml (MW: 8.475 kDa) Specificity Endogenous and recombinant human NT-proBNP. Precision In-between-run (n=8): ≤ 7 % CV Within-run (n=3): ≤ 3 % CV Cross-reactivity The assay does not cross react with rat, mouse, dog, or cat samples.
产品特点
保存建议
+4°C
其他
Biomedica Immunoassay(bmgrp)公司成立于1988年, 总部位于奥地利维也纳,主要致力于研究、开发和生产基于ELISA方法用于临床前研究相关标记物检测的工具。迄今为止Biomedica Immunoassay公司在心血管检测及骨代谢检测领域开发了一系列特色ELISA检测试剂盒,Biomedica Immunoassay的生产过程符合GMP/GLP指南,并符合ISO 9001:2015管理体系,有CE认证。Biomedica Immunoassay的产品根据FDA, EMEA和ICH指南进行验证,并具有验证报告。
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