Topotecan (Hycamtin) is a synthetic, potent and selective antagonist of the 5-HT3A channel derived from the plant alkaloid Camptothecin. Topotecan has an effective concentration of 10-200 μM and an IC50 of 114.1 μM for the 5-HT3A receptor.
产品描述
An Antagonist of 5-HT3A and an Agonist of 5-HT3B Receptors