BeKm-1 was originally isolated from Mesobuthus eupeus scorpion venom. BeKm-1 toxin blocked hERG1 channels expressed in HEK 293 cells with IC50 of 3.3 nM. The native toxin blocked M currents in differentiated mouse neuroblastoma X rat glioma NG108-15 cells with IC50 of 33 nM.
产品描述
A Novel ERG1 (KV11.1) K+ Channel Blocker
产品形式
BeKm-1 was originally isolated from Mesobuthus eupeus scorpion venom. BeKm-1 toxin blocked hERG1 channels expressed in HEK 293 cells with IC50 of 3.3 nM. The native toxin blocked M currents in differentiated mouse neuroblastoma X rat glioma NG108-15 cells with IC50 of 33 nM.