Plectreurys toxin (PLTX-II) is a 44 amino acid peptidyl toxin produced by Plectreurys tristis spider. PLTXII was found as a potent blocker for CaV2 channel (CAC) that inactivates Ca2+ currents in pupal neurons3 and in antennal lobe PNs of adult Drosophila brain. PLTX-II regulates the miniature excitatory postsynaptic current frequency at excitatory cholinergic synapses of these neurons in vitro and in situ and acts as a presynaptic Ca2+-channel blocker.
产品描述
An Inhibitor of CaV Channels
产品形式
Plectreurys toxin (PLTX-II) is a 44 amino acid peptidyl toxin produced by Plectreurys tristis spider. PLTXII was found as a potent blocker for CaV2 channel (CAC) that inactivates Ca2+ currents in pupal neurons3 and in antennal lobe PNs of adult Drosophila brain. PLTX-II regulates the miniature excitatory postsynaptic current frequency at excitatory cholinergic synapses of these neurons in vitro and in situ and acts as a presynaptic Ca2+-channel blocker.
