D-2-Amino-5-phosphopentanoic acid (D-AP5) is an NMDA receptor antagonist that competitively inhibits with the glutamate binding site of NMDA receptors with an IC50 value of 30 µM. D-AP5 has been shown to cause damage in memory and learning process and has the ability to trigger synaptic potentiation in mature hippocampus.
产品描述
A Competitive NMDA Receptor Antagonist
产品形式
D-2-Amino-5-phosphopentanoic acid (D-AP5) is an NMDA receptor antagonist that competitively inhibits with the glutamate binding site of NMDA receptors with an IC50 value of 30 µM. D-AP5 has been shown to cause damage in memory and learning process and has the ability to trigger synaptic potentiation in mature hippocampus.nBlockade by NMDA antagonists may cause glutamate-elicited calcium influx. In addition, it is known for its antinociceptive action.
