- 中文名称
烟碱型乙酰胆碱受体Alpha 4(胞外抗体(50 ul)
- 英文名字
- Anti-Nicotinic Acetylcholine Receptor Alpha 4 (extracellular
- 供应商
- Alomone
- 产品货号
- ALO-ANC-004-50
- 产品报价
- ¥已停产

- 产品说明书
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- 购买方式
- 银行转账、电汇、支票、现金,在线支付宝及网银支付,或直接与我们电话联系400-6800-868。
- 产品新闻

- 背景资料
- Acetylcholine, released by cholinergic neurons, activates two groups of acetylcholine receptors (AChRs); muscarinic AChRs (mAChRs) which belong to the superfamily of G-protein coupled receptors (GPCRs) and nicotinic AChRs (nAChRs) which belong to the ligand-gated ion channel superfamily. nAChRs also respond to nicotine, hence their name.nTo date, 17 different but related subunits of nAChRs have been identified and cloned. They consist of α subunits (α1-10), which is responsible for the binding of ligands. In fact, this subunit includes a Cys-loop in the first extracellular domain that is required for agonist binding. The other subunits responsible for making up the active receptor are the β (β1-4), γ, δ and ε subunits. Structurally, all subunits have the following: a conserved large extracellular N-terminal domain, 3 conserved transmembrane domains, a variable cytoplasmic loop and a fourth transmembrane domain with a short extracellular C-terminal domain. An active nAChR is generally a heteropentamer (homopentamers also exist) of these various subunits organized around a central pore
- 应用类型
- 经验证,该抗体可应用于IFC、IH、WB等实验应用,也可用于 IC、IP、LCI等实验。
- 免疫原
- Nicotinic Acetylcholine 受体 Alpha 4 (extracellular抗体的免疫原肽段为(C)DLVNMHSRVDQLD。此免疫原序列来源于190-202位氨基酸残基,该序列来源于人类nAChRα4 (Accession编号为P43681)。胞外,N端。
- 来源宿主
- 兔
- 反应性
- 反应性:人、 小鼠、 大鼠
- 保存建议
- 艾美捷为您提供的Nicotinic Acetylcholine 受体 Alpha 4 (extracellular抗体(50 ul)为室温运输,建议您收到产品后﹣20℃保存。
- 其他
- Alomone成立于1989年,已经成为全世界科学家信赖的最全面的离子通道研究工具供应商。产品覆盖离子通道、G蛋白耦联受体和神经信号研究所需的一抗、小分子、蛋白质和多肽等。所有Alomone产品均进行了生物实验验证,以冻干粉形式提供,可确保产品生物活性和保质期。Alomone可提供多种包装规格,灵活方便。作为Alomone Labs在中国的区域总代理,艾美捷科技有限公司将为中国客户提供最全面的Alomone Labs产品以及客户订制化服务。

- 注意
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该页面的中文产品信息的翻译,仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前,请浏览说明书确认。
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