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中文名称

NGF / proNGF中和抗体抗体(50 ug)

英文名字
NGF/proNGF Neutralizing Antibody
供应商
Alomone
产品货号
ALO-ALM-006-50
产品报价
¥已停产
产品说明书
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产品新闻
背景资料
NGF is purified in three forms: the 7S, 2.5S and β. The 7S, 130 kDa, form occurs naturally in mouse submaxillary glands, and is a multimeric protein composed of two α, one β and two γ subunits. The name is derived from its sedimentation co-efficient, 7S. The biologically active subunit is the β, which is a 26 kDa dimer composed of two identical 120 amino acid chains held together by hydrophobic interactions.5 The 2.5S form is 9 amino acids shorter than the β form, because of proteolysis that occurs during the purification process.6 The structural hallmark of all the neurotrophins is the characteristic arrangement of the disulfide bridges known as the cysteine knot, which has been found in other growth factors such as PDGF.7 There is a 95.8% homology between the rat and mouse forms, and a 85% homology between the human and mouse. nNGF has been shown to regulate neuronal survival, development function and plasticity.8 Recently, involvement of NGF in processes not involving neuronal cells has been shown, such as asthma,9 psoriasis10 and wound healing.The biological effects of NGF are mediated by two receptors: TrkA, which is specific for NGF, and p75, which binds all the neurotrophins.
应用类型
经验证,该抗体可应用于IE、N等实验。
免疫原
NGF/proNGF Neutralizing Antibody抗体的免疫原肽段为高度纯化蛋白:2。5 S小鼠NGF (Accession编号为P01139)。
来源宿主
小鼠
反应性
反应性:人、 小鼠、也可反应于: 大鼠
保存建议
艾美捷为您提供的NGF/proNGF Neutralizing Antibody抗体(50 ug)为室温运输,建议您收到产品后﹣20℃保存。
其他
Alomone成立于1989年,已经成为全世界科学家信赖的最全面的离子通道研究工具供应商。产品覆盖离子通道、G蛋白耦联受体和神经信号研究所需的一抗、小分子、蛋白质和多肽等。所有Alomone产品均进行了生物实验验证,以冻干粉形式提供,可确保产品生物活性和保质期。Alomone可提供多种包装规格,灵活方便。作为Alomone Labs在中国的区域总代理,艾美捷科技有限公司将为中国客户提供最全面的Alomone Labs产品以及客户订制化服务。
注意
该页面的中文产品信息的翻译,仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前,请浏览说明书确认。
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