TXN2 encodes a mitochondrial member of the thioredoxin family, a group of small multifunctional redox-active proteins. The encoded protein may play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis. TXN2 (Thioredoxin 2) is a Protein Coding gene. Diseases associated with TXN2 include Combined Oxidative Phosphorylation Deficiency 29 and Ocular Hypertension. Among its related pathways are Cellular Senescence (REACTOME) and Fluid shear stress and atherosclerosis.