NSUN5 (NOP2/Sun RNA Methyltransferase Family Member 5) encodes a member of an evolutionarily conserved family of proteins that may function as methyltransferases. NSUN5 is located in a larger region of chromosome 7 that is deleted in Williams-Beuren syndrome, a multisystem developmental disorder. There are two pseudogenes for NSUN5 located in the same region of chromosome 7. Alternative splicing results in multiple transcript variants encoding different isoforms.
