MYH2 (Myosin Heavy Chain 2) is a Protein Coding gene. Diseases associated with MYH2 include Proximal Myopathy And Ophthalmoplegia and Inclusion Body Myositis. Among its related pathways are Sertoli-Sertoli Cell Junction Dynamics and Actin Nucleation by ARP-WASP Complex. Myosins are actin-based motor proteins that function in the generation of mechanical force in eukaryotic cells. Muscle myosins are heterohexamers composed of 2 myosin heavy chains and 2 pairs of nonidentical myosin light chains. MYH2 encodes a member of the class II or conventional myosin heavy chains, and functions in skeletal muscle contraction. MYH2 is found in a cluster of myosin heavy chain genes on chromosome 17.
