Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution，subcellular localization，immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene，is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia，an autosomal recessive disorder characterized by hyperammonemia.
应用类型
IHC, FC, WB
免疫原
KLH conjugated synthetic peptide between 293-322 amino acids from the C-terminal region of human ARG1.
