- 中文名称
VEGF-A（猪）ELISA试剂盒
- 英文名字
- VEGF-A (pig) ELISA kit
- 供应商
- Bertin Bioreagent
- 产品货号
- A05426
- 产品报价
- ￥询价/96wells
- 产品说明书
- 点击查看
- 购买方式
- 90%产品中国有现货库存。银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系400-6800-868
- 产品新闻
- 背景资料
- Enzyme ImmunoAssay (EIA) is a technique to detect and quantify antigens (proteins, hormones…) or antibodies in samples. It relies on the ability of an antibody to bind a specific antigen. Either the antibody or the antigen is labelled with an enzyme whose substrate is a chromogen or a fluorogen converted in a measurable product (color or fluorescence).|Enzyme-linked Immunosorbent Assay (ELISA) is a type of EIA using a solid phase (ex: microtiter plate) coated with an antigen immobilizing the molecule to detect. Over the time, scientists have extended the term ELISA to EIAs using an antibody coating the solid phase. That explains why our EIA kits using coated antibodies are also called ELISA kits.|Vascular endothelial growth factor (VEGF-A or VEGF)(1), also known as vascular permeability factor (VPF)(2), has been discovered in 1983. It is a member of the VEGF family that includes in mammals placental growth factor (PLGF), VEGF-B, VEGF-C, and VEGF-D (also known as c-Fos-induced growth factor, FIGF)(1).|VEGF-A is a glycoprotein having several isoforms of 121 to 206 amino acids(1) with a molecular weight from 33 kDa to 57kDa. It is a homodimer stabilised by hydrophobic interactions and by a disulphide bound(3). The monomer structure contains a central antiparallel four-stranded β sheet with a cystine knot at the end (4).|VEGF-A is produced by many cells like fetal tissu, hematopoietic stem cells, epidermal keratinocytes, podocytes of the renal glomerulus, cardiac myocytes, prostatic epithelium, and certain epithelial cells of the adrenal cortex and lung(5). |The main function of the VEGF-A is the angionesis (formation of new capillaries from pre-existing vessels) during the embryogenesis(1) or during re-building of the blood vessel after an injury. It has also some secondary functions in the chemotacxis of macrophages/ granulocytes and in vasodilation (indirectly by NO release).|Due to its main function, overexpression of VEGF-A causes various diseases including cancer.
- 产品描述
- 酶免疫测定（EIA）是一种检测和定量样品中抗原（蛋白质、激素等）或抗体的技术。它依赖于抗体结合特定抗原的能力。用酶标记抗体或抗原，所述酶的底物是转化成可测量产物（颜色或荧光）的色原或荧光团。|酶联免疫吸附测定（ELISA）是使用固相（例如：微量滴定板）上包被有固定分子的抗原以进行检测。随着时间的推移，科学家们已经将术语ELISA扩展到使用抗体包被固相的EIA。这就解释了为什么我们使用包被抗体的EIA试剂盒也被称为ELISA试剂盒。|血管内皮生长因子（VEGF-A或VEGF）（1），也称为血管通透性因子（VPF）（2），于1983年发现。它是VEGF家族的成员，在哺乳动物中包括胎盘生长因子（PLGF）、VEGF-B、VEGF-C和VEGF-D（也称为c-Fos诱导的生长因子，FIGF）（1）。| VEGF-A是具有121至206个氨基酸（1）的几种同种型的糖蛋白，分子量为33 kDa至57 kDa。它是一种通过疏水相互作用和二硫键稳定的同源二聚体（3）。单体结构含有中心反平行四链β折叠，末端有胱氨酸结（4）。| VEGF-A由许多细胞产生，如胎儿组织、造血干细胞、表皮角质形成细胞、肾小球足细胞、心肌细胞、前列腺上皮以及肾上腺皮质和肺的某些上皮细胞（5）。|VEGF-A的主要功能是在胚胎发生（1）期间或在损伤后血管重建期间的血管新生（从预先存在的血管形成新的毛细血管）。它还在巨噬细胞/粒细胞的趋化作用和血管舒张（间接通过NO释放）中具有一些次要功能。|由于其主要功能，VEGF-A的过表达引起包括癌症在内的各种疾病。
- 产品特点
- 该VEGF-A（猪）ELISA试剂盒,VEGF-A (pig) ELISA kit产品产品特点详情查看产品说明书。
- 保存建议
- Store at +4degrees; shelf life 6months maximum after production
- 其他
- 法国Bertin Technologies公司是一家大型仪器设备及试剂供应商，拥有50多年的历史，产品涉及卫生、环境、安全甚至军工等诸多领域。Bertin Bioreagent是Bertin Technologies集团的生物试剂部门，主要是致力于研发与炎症，氧化损伤，内分泌学，糖尿病，肥胖症，高血压，精神药理学，癌症，哮喘，朊病毒疾病，药代动力学和代谢等相关的化学试剂 ，蛋白，底物，抗体及检测试剂盒等产品。 Bertin Instruments是Bertin Technologies集团的仪器部门，其中旗舰产品Precellys系列多功能生物样品匀浆器是全世界各个实验室的明星产品，截至目前累计有15000+的引文！
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- 注意
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该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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