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中文名称

Acylated Ghrelin(小鼠,大鼠)Express ELISA试剂盒

英文名字
Acylated Ghrelin (mouse, rat) Express ELISA kit
供应商
Bertin Bioreagent
产品货号
A05117
产品报价
¥询价/96wells
产品说明书
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购买方式
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产品新闻
背景资料
Enzyme ImmunoAssay (EIA) is a technique to detect and quantify antigens (proteins, hormones…) or antibodies in samples. It relies on the ability of an antibody to bind a specific antigen. Either the antibody or the antigen is labelled with an enzyme whose substrate is a chromogen or a fluorogen converted in a measurable product (color or fluorescence).|Enzyme-linked Immunosorbent Assay (ELISA) is a type of EIA using a solid phase (ex: microtiter plate) coated with an antigen immobilizing the molecule to detect. Over the time, scientists have extended the term ELISA to EIAs using an antibody coating the solid phase. That explains why our EIA kits using coated antibodies are also called ELISA kits.|Bertin Bioreagent’s expertise is to develop analytical tools for biomarkers. As such, in 2004, Bertin Bioreagent launched its first Ghrelin Biomarker assay kits, under the SPI-Bio brand name, as a result of its state-of-the-art R&D research teams. Bertin Bioreagent was the first company providing bioanalytical tools to assay Acylated and Non-acylated Ghrelin with very high sensitivity.|Ghrelin discovered in 1999, is fast becoming an endocrinology target of the millennium. Ghrelin, identified in rat stomach as an endogenous ligand for the GH secretagogue receptor, is mainly produced in stomach, but has been demonstrated in many other organs. In addition to GH-releasing properties and its orexant action, ghrelin could act as an hormone having effects on gastric motility (similarity with the peptide hormone motilin), acidic secretion, cardiovascular action, antiproliferative effects, pancreatic and glucose metabolism function, sleep... Ghrelin gene raises to mRNA prepro-ghrelin of 117 amino acids. This precursor is processed into ghrelin, 28 amino acids (human). Before being secreted, this peptide is octanoylated at Ser 3. This step is essential for biological activity. If the endogenous peptide appears directly related to feeding behaviour, the potential therapeutic importance of this hormone is not restricted to a regulator of food intake but also may be involved osteoporosis somatopaus, infertility and ovulation induction, and some cardiovascular diseases.
产品描述
酶免疫测定(EIA)是一种检测和定量样品中抗原(蛋白质、激素等)或抗体的技术。它依赖于抗体结合特定抗原的能力。用酶标记抗体或抗原,所述酶的底物是转化成可测量产物(颜色或荧光)的色原或荧光团。|酶联免疫吸附测定(ELISA)是使用固相(例如:微量滴定板)上包被有固定分子的抗原以进行检测。随着时间的推移,科学家们已经将术语ELISA扩展到使用抗体包被固相的EIA。这就解释了为什么我们使用包被抗体的EIA试剂盒也被称为ELISA试剂盒。| Bertin Bioreagent的专长是开发生物标志物的分析工具。因此,2004年,Bertin Bioreagent以SPI-Bio品牌推出了其第一个Ghrelin生物标志物检测试剂盒,这是其最先进的研发团队的结果。Bertin Bioreagent是第一家提供生物分析工具以非常高的灵敏度测定酰化和非酰化Ghrelin的公司。| Ghrelin于1999年发现,正迅速成为千年内分泌学的目标。Ghrelin在大鼠胃中被鉴定为GH促分泌素受体的内源性配体,主要在胃中产生,但已被证明在许多其他器官中产生。除了GH释放特性和其食欲作用之外,ghrelin可以作为一种激素,对胃运动(与肽激素胃动素相似)、酸性分泌、心血管作用、抗增殖作用、胰腺和葡萄糖代谢功能、睡眠和呼吸等具有影响。Ghrelin基因表达为117个氨基酸的前Ghrelin原。这种前体被加工成生长素释放肽,28个氨基酸(人)。在被分泌之前,该肽在Ser 3处被辛酰化。这一步骤对于生物活性至关重要。如果内源性肽与摄食行为直接相关,则这种激素的潜在治疗重要性不仅限于食物摄入的调节剂,而且还可能涉及骨质疏松症、不孕症和排卵诱导以及一些心血管疾病。
产品特点
该Acylated Ghrelin(小鼠,大鼠)Express ELISA试剂盒,Acylated Ghrelin (mouse, rat) Express ELISA kit产品产品特点详情查看产品说明书。
保存建议
Store at -20degrees; shelf life 2 years maximum after production
其他
法国Bertin Technologies公司是一家大型仪器设备及试剂供应商,拥有50多年的历史,产品涉及卫生、环境、安全甚至军工等诸多领域。Bertin Bioreagent是Bertin Technologies集团的生物试剂部门,主要是致力于研发与炎症,氧化损伤,内分泌学,糖尿病,肥胖症,高血压,精神药理学,癌症,哮喘,朊病毒疾病,药代动力学和代谢等相关的化学试剂 ,蛋白,底物,抗体及检测试剂盒等产品。 Bertin Instruments是Bertin Technologies集团的仪器部门,其中旗舰产品Precellys系列多功能生物样品匀浆器是全世界各个实验室的明星产品,截至目前累计有15000+的引文!
注意
该页面的中文产品信息的翻译,仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前,请浏览说明书确认。
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