The protein encoded by this gene specifies the cardiac
muscle family member of the calsequestrin family. Calsequestrin is
localized to the sarcoplasmic reticulum in cardiac and slow
skeletal muscle cells. The protein is a calcium binding protein
that stores calcium for muscle function. Mutations in this gene
cause stress-induced polymorphic ventricular tachycardia, also
referred to as catecholaminergic polymorphic ventricular
tachycardia 2 (CPVT2), a disease characterized by bidirectional
ventricular tachycardia that may lead to cardiac arrest. [provided
by RefSeq].
