Cytochrome p450 belongs to an enzyme superfamily that catalyzes many reactions such as the synthesis of cholesterol, lipids, steroids by oxidizing the compounds and plays a role in drug metabolism. The protein has been known to be stimulated by cigarette smoke. On-going studies link the cytochrome p450 protein with lung cancer. In the liver microsome, it is part of the NADPH-dependent electron transport pathway. The protein has been found expressed in the lung, lymphocytes and placenta. Anti-Cytochrome p450 antibody is useful for researchers interested in cancer research and enzyme research.
Anti-Cytochrome p450 antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal portion of human cytochrome p450 conjugated to Keyhole Limpet Hemocyanin (KLH).
来源宿主
Rabbit
反应性
H. sapiens (Human); Rattus (Rat)
保存建议
Store vial at -20° C or below prior to opening. This vial contains a relatively low volume of reagent (25 µL). To minimize loss of volume dilute 1:10 by adding 225 µL of the buffer stated above directly to the vial. Recap, mix thoroughly and briefly centrifuge to collect the volume at the bottom of the vial. Use this intermediate dilution when calculating final dilutions as recommended below. Store the vial at -20°C or below after dilution. Avoid cycles of freezing and thawing.
