p90 RSK2 Antibody detects p90 RSK2 protein. The p90 ribosomal S6 kinases (RSK)1–4 are downstream members of the extracellular signal-regulated kinase (ERK)/MAPK cascade. The loss of RSK2 activity in humans leads to Coffin–Lowry syndrome, which is characterized by mental retardation and growth deficits. Recent work suggests that RSK2 exerts a tonic regulation on G-protein coupled signaling. RSK1 is studied in cancer research and is known to inactive tumor supressor complexes and death kinases. Anti-p90 RSK1 Antibody is ideal for investigators involved in Neuroscience, Cell Signaling, and Cancer research.
应用类型
Western Blot,
免疫原
Anti-p90 RSK2 Antibody was produced by repeated immunizations with a synthetic peptide corresponding to amino acid residues from the C-terminal region.
来源宿主
Rabbit
反应性
H. sapiens (Human)
保存建议
Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
