Tripeptidyl-peptidase I (TPP1), also known as CLN2, is a lysosomal serine protease detected in all tissues examined, with highest levels shown in heart and placenta. It is an aminopeptidase that cleaves tripeptides from the free N-terminus of polypeptides and may also have endopeptidase activity. Defects in TPP1 are the cause of classical late-infantile neuronal ceroid lipofusionosis, also known as ceroid lipofusionosis neuronal 2 (CLN2), a fatal childhood neurodegenerative disease characterized by progressive visual and mental decline, motor disturbance, epilepsy, and behavioral changes.
应用类型
WB
免疫原
该Anti-Human CLN-2的详细信息查看ReliaTech提供的产品说明书。
来源宿主
该Anti-Human CLN-2的详细信息查看ReliaTech提供的产品说明书。
反应性
该Anti-Human CLN-2的详细信息查看ReliaTech提供的产品说明书。
保存建议
该Anti-Human CLN-2的详细信息查看ReliaTech提供的产品说明书。溶解建议：Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
