Cathepsin S is a lysosomal cysteine protease of the papain family. It plays a major role in the processing of the MHC class IIassociatedinvariant chain. It has been implicated in the pathogenesis of several diseases such as Alzheimer’s disease and degenerative disorders associated with the cells of the mononuclear phagocytic system. Human Cathepsin S is synthesized as a preproenzyme of 331 amino acid residues consisting a signal peptide (residues 116), a pro region (residues 17-114), and the mature enzyme (residues 115-331). Cathepsin S is less abundant in tissues than Cathepsins B, L and H. The highest levels have been found in lymph nodes, spleen, macrophages and other phagocytic cells.
应用类型
WB
免疫原
该Anti-Human Cathepsin S的详细信息查看ReliaTech提供的产品说明书。
来源宿主
该Anti-Human Cathepsin S的详细信息查看ReliaTech提供的产品说明书。
反应性
该Anti-Human Cathepsin S的详细信息查看ReliaTech提供的产品说明书。
保存建议
该Anti-Human Cathepsin S的详细信息查看ReliaTech提供的产品说明书。溶解建议：Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
