WEE1 is a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases that catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase (1). WEE1 is highly expressed in testis. WEE1 kinase phosphorylated the p34 (CDC2) -cyclin B complex on tyr15 and inactivated the p34 (CDC2)-cyclin B kinase (2). WEE1 Protein is ideal for investigators involved in Signaling Proteins, Cellular Proteins, Cancer, Cell Cycle, and Cytoplasmic Tyrosine Kinases research.
序列
该【干冰】WEE1 recombinant protein-GST fusion protein - 009-001-U59的详细信息查看Rockland提供的产品说明书。
来源宿主
该【干冰】WEE1 recombinant protein-GST fusion protein - 009-001-U59的详细信息查看Rockland提供的产品说明书。
溶解建议
该【干冰】WEE1 recombinant protein-GST fusion protein - 009-001-U59的详细信息查看Rockland提供的产品说明书。
保存建议
Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
