UBE2J1 is a member of the E2 ubiquitin-conjugating enzyme family which is located in the membrane of the endoplasmic reticulum (ER) and may contribute to quality control ER-associated degradation by the ubiquitin-proteasome system. UBE2J1 play an important role in the homeostatic regulation of MHC class I assembly and expression (1). HRD1 and UBE2J1 associate in a complex together with non-β2m bound MHC class I heavy chains, Derlin 1, and p97 and discriminate misfolded MHC class I from conformational MHC I-β2m-peptide heterotrimers. UBE2J1 Protein is ideal for investigators involved in Signaling Proteins, Ubiquitin Proteins, Cancer, Cell Cycle, and Neurobiology research.
序列
该【干冰】UBE2J1 recombinant protein-GST fusion protein - 009-001-U38的详细信息查看Rockland提供的产品说明书。
来源宿主
该【干冰】UBE2J1 recombinant protein-GST fusion protein - 009-001-U38的详细信息查看Rockland提供的产品说明书。
溶解建议
该【干冰】UBE2J1 recombinant protein-GST fusion protein - 009-001-U38的详细信息查看Rockland提供的产品说明书。
保存建议
Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
