UBA2 (SAE2) or ubiquitin-like modifier activating enzyme 2 forms a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins. The posttranslational modification of proteins by the addition of the small protein SUMO, or sumoylation, regulates protein structure and intracellular localization (1). UBA2 functions in SUMO1 activation in a manner analogous to the single E1 ubiquitin-activating enzymes (2). The inactivation of UBA2 may be a therapeutic strategy in MYC-driven cancers. UBA2 Protein is ideal for investigators involved in Signaling Proteins, Ubiquitin Proteins, Cancer, Cell Cycle, and Neurobiology research.
序列
该【干冰】UBA2(SAE2) recombinant protein-GST fusion protein - 009-001-U25的详细信息查看Rockland提供的产品说明书。
来源宿主
该【干冰】UBA2(SAE2) recombinant protein-GST fusion protein - 009-001-U25的详细信息查看Rockland提供的产品说明书。
溶解建议
该【干冰】UBA2(SAE2) recombinant protein-GST fusion protein - 009-001-U25的详细信息查看Rockland提供的产品说明书。
保存建议
Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
