SETMAR or SET domain and mariner transposase fusion gene is a nonhomologous end-joining repair protein that regulates genomic integration of exogenous DNA by opening chromatin and facilitating joining of DNA ends (1). SETMAR has histone methyltransferase activity and methylates 'Lys-4' and 'Lys-36' of histone H3. SETMAR also has DNA nicking activity and may play a role in DNA repair (2). Human Pso4 forms a stable complex with SETMAR that regulates Metnase function in DNA repair. SETMAR has sequence-specific DNA-binding activity and recognizes the 19-mer core of the 5'-terminal inverted repeats (TIRs) of the Hsmar1 element. SETMAR Protein is ideal for investigators involved in Signaling Proteins, Acetyl/Methyltransferase Proteins, Apoptosis/Autophagy, Cancer, Cell Cycle, and Neurobiology research.
序列
该【干冰】SETMAR recombinant protein-GST fusion protein - 009-001-T30S的详细信息查看Rockland提供的产品说明书。
来源宿主
该【干冰】SETMAR recombinant protein-GST fusion protein - 009-001-T30S的详细信息查看Rockland提供的产品说明书。
溶解建议
该【干冰】SETMAR recombinant protein-GST fusion protein - 009-001-T30S的详细信息查看Rockland提供的产品说明书。
保存建议
Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
