Mortalin is a mitochondrial chaperone and a member of the heat shock protein 70 family that is constitutively expressed in cells. Mortalin plays a central role in mitochondrial biogenesis through its capacity to direct the import of nuclear-encoded proteins into the mitochondria. Mortalin plays a role in the control of cell proliferation and elevated levels of mortalin have correlated with malignant transformation and poor cancer prognosis. Mortalin can support cancer cell resistance to complement-dependent cytotoxicity (1). Mortalin expression was decreased in the mitochondrial fraction of neurons from the substantia nigra of Parkinson disease patients (2). Mortalin Protein is ideal for investigators involved in Signaling Proteins, Cell Stress & Chaperone Proteins, Apoptosis/Autophagy, and Cancer research.
序列
该【干冰】Mortalin recombinant protein-GST fusion protein - 009-001-S51S的详细信息查看Rockland提供的产品说明书。
来源宿主
该【干冰】Mortalin recombinant protein-GST fusion protein - 009-001-S51S的详细信息查看Rockland提供的产品说明书。
溶解建议
该【干冰】Mortalin recombinant protein-GST fusion protein - 009-001-S51S的详细信息查看Rockland提供的产品说明书。
保存建议
Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
