- 中文名称
【干冰】MDM4(1-137) recombinant protein-HIS Epitope - 009-001-S46S
- 英文名字
- 【干冰】MDM4(1-137) recombinant protein-HIS Epitope - 009-001-S46S
- 供应商
- Rockland
- 产品货号
- 009-001-S46S
- 产品报价
- ￥询价/20ug
- 产品说明书
- 点击查看
- 购买方式
- 90%产品中国有现货库存。银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系400-6800-868
- 产品新闻
- 背景资料
- MDM4 is a nuclear protein that contains a p53 binding domain at the N-terminus and a RING finger domain at the C-terminus. MDM4 shows structural similarity to p53-binding protein MDM2 and both proteins bind the p53 tumor suppressor protein and inhibit its activity. However, unlike MDM2, MDM4 does not cause nuclear export or degradation of p53. Instead, MDM4 inhibits p53 activity by binding to the transcriptional activation domain of p53. MDM4 is overexpressed in a variety of human cancers (1). Expression level of MDM4 is significantly higher in chronic lymphocytic leukemia. MDM4 is a specific chemotherapeutic target for treating retinoblastoma (2). MDM4 Protein is ideal for investigators involved in Signaling Proteins, Cell Cycle Proteins, AKT/PKB Pathway, Apoptosis/Autophagy, Cancer, Cell Cycle, and Cellular Stress research.
- 序列
- 该【干冰】MDM4(1-137) recombinant protein-HIS Epitope - 009-001-S46S的详细信息查看Rockland提供的产品说明书。
- 来源宿主
- 该【干冰】MDM4(1-137) recombinant protein-HIS Epitope - 009-001-S46S的详细信息查看Rockland提供的产品说明书。
- 溶解建议
- 该【干冰】MDM4(1-137) recombinant protein-HIS Epitope - 009-001-S46S的详细信息查看Rockland提供的产品说明书。
- 保存建议
- Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
- 其他
- Rockland成立于1962年，是一家老牌抗体原产企业，其位于美国费城郊区的农场保有近20种实验动物。Rockland公司为生命科学领域提供丰富的、高质量的抗体，包括载脂蛋白、细胞周期/凋亡、细胞因子、细胞信号蛋白、酶类、细胞外基质、转录因子(NFkB)和泛素（Ubiquitin）等识别抗体，应用范围包括Western blot、免疫组化、免疫荧光和ELISA等。另外，Rockland也生产特别齐全的二抗，包括纯化、生物素、HRP/ALP、荧光标记二抗，应用十分广泛。
- 注意
-
该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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