HO1 (Heme oxygenase 1) catalyzes the oxidative cleavage of heme to biliverdin and is one of the main genes controlling heme synthesis and catabolism. HO1 plays a protective role in various disorders and can ameliorate experimental MN via multiple pathways, including anti-oxidative and immunomodulatory effects (1). Exposure of primary hepatocytes to carbon monoxide and nitric oxide results in dramatic induction of HO1 in dose- and time-dependent manner and this induction is blocked by MAP kinase inhibitors (MAPKs) but not by inhibitors of PI3 kinase pathway (2). HO1 Protein is ideal for investigators involved in Signaling Proteins, Cell Stress & Chaperone Proteins, Cancer, Cardiovascular Disease, Cellular Stress, Inflammation, and Neurobiology research.
序列
该【干冰】HO1 recombinant protein-GST fusion protein - 009-001-S03的详细信息查看Rockland提供的产品说明书。
来源宿主
该【干冰】HO1 recombinant protein-GST fusion protein - 009-001-S03的详细信息查看Rockland提供的产品说明书。
溶解建议
该【干冰】HO1 recombinant protein-GST fusion protein - 009-001-S03的详细信息查看Rockland提供的产品说明书。
保存建议
Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
