It is a cytotoxic nitrogen mustard derivative widely used in cancer chemotherapy. It cross-links DNA, causes strand breakage, and induces mutations. Its clinical activity is associated with a decrease in aldehyde dehydrogenase 1 (ALDH1) activity. This substance is listed as a known human carcinogen.Melting Point:41-45°CSolubility:Chloroform (Slightly), Methanol (Slightly) Method for Determining Identity:Proton NMR Spectroscopic and Mass Spectrometric AnalysisWater:~7.0%TLC Conditions:SiO2; Dichloromethane: Methanol = 9:1; Visualized with UV, Ninhydrin and KMnO4; Single spot; Rf=0.45Storage and Stability:May be stored at RT for short-term only. Long-term storage is recommended at 4°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
