Parathyroid hormone (pTH) is the most important endocrine regulator of Ca2+ and phosphorus concentration in the extracellular fluid. pTH is secreted from cells of the parathyroid glands and acts for the most part via the binding to specific G-protein coupled receptors on the surface of target cells in bone and kidney, utilizing the second messenger adenylate cyclase to regulate cAMP levels in cells. Like most other protein hormones, parathyroid hormone is synthesized as a preprohormone and is processed intracellularly. The mature hormone, 84 amino acids in length, is released from secretory vesicles into the blood. Biologic effects of large C-terminal parathyroid hormone (PTH) fragments, such as pTH 7-84, are thought to regulate PTH secretion via an autocrine/paracrine regulatory mechanism
序列
该Parathyroid hormone (pTH) Rat 4-13 Peptide - 000-001-M29的详细信息查看Rockland提供的产品说明书。
来源宿主
该Parathyroid hormone (pTH) Rat 4-13 Peptide - 000-001-M29的详细信息查看Rockland提供的产品说明书。
溶解建议
Restore with deionized water (or equivalent)
保存建议
Store vial at 2 - 8 ° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. Dilute only prior to immediate use.
