[干冰]磷脂酰肌醇(3,5)二磷酸二辛酯(PI(3,5)P2 diC8)-PI(3,5)P2 diC8

PI(3,5)P2 diC8（磷脂酰肌醇3,5-二磷酸二油酸酯） 是一种合成的、纯化的二油酸基PI(3,5)P2。

磷脂酰肌醇（PIPns） 是细胞膜的次要成分，但却是细胞通信中不可或缺的信号分子。磷脂酰肌醇3,5-二磷酸 含量极低，对于从溶酶体和晚期内体向高尔基体的逆向膜运输至关重要，并且参与自噬过程。PI(3,5)P2的水平由5-激酶PIKfyve和5-磷酸酶Fig4/Sac3调控，其失调与多种人类神经病变有关（例如夏科-马里-图斯病）。

艾美捷[干冰]磷脂酰肌醇(3,5)二磷酸二辛酯(PI(3,5)P2 diC8)：

货号：P-3508

关键词：二油酸基磷脂酰肌醇3,5-二磷酸、PtdIns(3,5)P2 (8:0/8:0)、PI(3,5)P2 C8

分类：脂质

筛选：diC8、磷脂酰肌醇、PI(3,5)P2

CAS编号：299216-96-9

分子式：C25H44Na5O19P3

分子量（g/mol）：856.48

纯度：95%

储存：-20°C或更低

运输温度：根据目的地不同，采用干冰或凝胶冰运输

[干冰]磷脂酰肌醇(3,5)二磷酸二辛酯(PI(3,5)P2 diC8)文献参考：

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3. Ikonomov, O. C., D. Sbrissa, et al. (2009). “Sac3 is an insulin-regulated phosphatidylinositol 3,5-bisphosphate phosphatase: gain in insulin responsiveness through Sac3 down-regulation in adipocytes.” J Biol Chem 284(36): 23961-71.

4. Silswal, N., et al. (2011). “Phosphatidylinositol 3,5-bisphosphate increases intracellular free Ca2+ in arterial smooth muscle cells and elicits vasocontraction.” Am J Physiol Heart Circ Physiol 300(6): H2016-2026.

5. Kirsch, S. A., et al. (2018). “Phosphatidylinositol-3, 5-bisphosphate lipid-binding-induced activation of the human two-pore channel 2.” Cellular and Molecular Life Sciences: 1-13.