[干冰]1-羟基-2-甲基-2-丁烯-4-基-4-二磷酸(HDMAPP)：高效VγVδ T细胞激活剂

异戊二烯类化合物 是一类多样化的天然产物，是所有细胞中必不可少的成分。异戊二烯类化合物是由简单的前体异戊二烯焦磷酸（IPP）和二甲基烯丙基焦磷酸（DMAPP）生物合成而来的。真核生物、真菌和某些革兰氏阳性菌通过甲羟戊酸（MVA）途径产生IPP，而革兰氏阴性菌和某些革兰氏阳性菌则利用非甲羟戊酸途径或2-C-甲基-D-赤藓糖醇-4-磷酸（MEP）途径。**1-羟基-2-甲基-2-丁烯-4-基-4-二磷酸（HDMAPP或HMBPP）是非甲羟戊酸途径中的一个中间体，由2-C-甲基-D-赤藓糖醇-2,4-环磷酸（cMEPP）**通过IspG（GcpE）生物合成而来。它是IspH（LytB）的底物，生成IPP和DMAPP。此外，HDMAPP是迄今为止发现的最有效的VγVδ T细胞激活剂。

艾美捷[干冰]1-羟基-2-甲基-2-丁烯-4-基-4-二磷酸(HDMAPP)：

货号：I-M055

分类：生化试剂

筛选：异戊二烯焦磷酸、MEP途径

CAS编号：396726-03-7

分子式：C5H21N3O8P2

分子量（g/mol）：313.18

纯度：95%

储存：-20°C或更低

运输温度：凝胶冰

[干冰]1-羟基-2-甲基-2-丁烯-4-基-4-二磷酸(HDMAPP)文献参考：

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