反式-反式法呢基焦磷酸(FPP)是异戊二烯生物合成中的一个中间体。异戊二烯化合物是一类多样的天然产物,是所有细胞中的必需成分。异戊二烯化合物是由简单的前体异戊烯基焦磷酸(IPP)和二甲基烯丙基焦磷酸(DMAPP)生物合成的。真核生物、真菌和一些革兰氏阳性菌通过甲羟戊酸(MVA)途径产生IPP,而革兰氏阴性菌和一些革兰氏阳性菌则利用非甲羟戊酸途径或2-C-甲基-D-赤藓糖醇-4-磷酸(MEP)途径。FPP是由法呢基焦磷酸合酶催化DMAPP与两个IPP单位缩合形成的。
艾美捷法尼基二磷酸(FPP):
货号:I-0150
提供形式:三铵盐形式
分类:生化试剂
筛选:异戊二烯、异戊二烯焦磷酸
CAS编号:104715-19-7
分子式:C15H37N3O7P2
分子量(g/mol):433.42
纯度:95%
储存:-20°C或更低
运输温度:凝胶冰
法尼基二磷酸(FPP)文献参考:
1. Voynova, N. E., S. E. Rios, et al. (2004). “Staphylococcus aureus mevalonate kinase: isolation and characterization of an enzyme of the isoprenoid biosynthetic pathway.” J Bacteriol 186(1): 61-7.
2. Martin, D. M., J. Faldt, et al. (2004). “Functional Characterization of Nine Norway Spruce TPS Genes and Evolution of Gymnosperm Terpene Synthases of the TPS-d Subfamily.” Plant Physiol 135(4): 1908-1927.
3. Gibot, L., J. Follet, et al. (2009). “Human caspase 7 is positively controlled by SREBP-1 and SREBP-2.” Biochem J 420(3): 473-83.
4. Falara, V., Akhtar, T. A., Nguyen, T. T. H., Spyropoulou, E. A., Bleeker, P. M., Schauvinhold, I., … Pichersky, E. (2011). “The tomato terpene synthase gene family.” Plant Physiology, 157(2), 770-789. DOI: 10.1104/pp.111.179648
5. Sugimoto, H., et al. (2017). “Bioanalysis of farnesyl pyrophosphate in human plasma by high-performance liquid chromatography coupled to triple quadrupole tandem mass spectrometry and hybrid quadrupole Orbitrap high-resolution mass spectrometry.” Anal Bioanal Chem 409(14): 3551-3560.
6. Muchlinski, A., et al. (2019). “Biosynthesis and Emission of Stress-Induced Volatile Terpenes in Roots and Leaves of Switchgrass (Panicum virgatum L.).” Frontiers in Plant Science 10(1144).
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