EpiQuik? m6A RNA 甲基化定量试剂盒（比色法）是一整套优化的缓冲液和试剂，用于对 RNA 中的 N6-甲基腺苷（m6A 或 6mA）进行比色定量。它适用于使用从任何物种（如哺乳动物、植物、真菌、细菌和病毒）分离的总 RNA 直接检测 m6A RNA 甲基化状态。该套件具有以下优点和特点：
| 产品名称 | 货号 | 规格 |
EpiQuik m6A RNA Methylation Quantification Kit (Colorimetric) | P-9005-48 P-9005-96 | 48 次反应 96 次反应 |
EpiQuik m6A RNA 甲基化定量试剂盒特色和优势：
使用 m6A 抗体进行类似比色 ELISA 的检测，步骤简单易懂，方便快捷。整个过程可以在 3 小时 45 分钟内完成。
高灵敏度，其中检测限可低至 10 pg 的 m6A。
独特的结合溶液使 RNA >70 nts 能够紧密结合到孔中，从而能够定量 mRNA 和 ncRNA（如 tRNA、rRNA 和 snRNA）中的 m6A。
优化的抗体和增强子溶液对 m6A 具有高度特异性，在样品 RNA 的指定浓度范围内与未甲基化的腺苷没有交叉反应性。
包括通用阳性和阴性对照，适用于定量任何物种的 m6A。
条孔微孔板规格使分析灵活，可用于手动或高通量分析。
简单、可靠且一致的分析条件。
EpiQuik m6A RNA 甲基化定量试剂盒 6868篇发表的文献：
| 发表时间 | 文章标题 | 作者 | 杂志名称 |
| 2016/10/27 | Electrochemical immunosensor for N6-methyladenosine detection in human cell lines based on biotin-streptavidin system and silver-SiO2 signal amplification. | Yin H, Wang H, Jiang W, Zhou Y, Ai S | Biosens Bioelectron |
| 2020/2/3 | Level of N6-Methyladenosine in Peripheral Blood RNA: A Novel Predictive Biomarker for Gastric Cancer | Ge L et. al. | Clinical Chemistry |
| 2016/4/5 | Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m6A-demethylation of NANOG mRNA. | Zhang C, Samanta D, Lu H, Bullen JW, Zhang H, Chen I, He X, Semenza GL | Proc Natl Acad Sci U S A |
| 2016/1/5 | NIPBL Controls RNA Biogenesis to Prevent Activation of the Stress Kinase PKR. | Yuen KC, Xu B, Krantz ID, Gerton JL | Cell Rep |
| 2016/11/24 | Hsa-miR-520d-5p promotes survival in human dermal fibroblasts exposed to a lethal dose of UV irradiation | Ishihara Y, et al. | npj Aging and Mechanisms of Disease |
| 2017/2/8 | Downregulation of Methyltransferase Dnmt2 Results in Condition-dependent Telomere Shortening and Senescence or Apoptosis in Mouse Fibroblasts. | Lewinska A, Adamczyk-Grochala J, Kwasniewicz E, Wnuk M | J Cell Physiol |
| 2017/3/23 | m6A Demethylase ALKBH5 Maintains Tumorigenicity of Glioblastoma Stem-like Cells by Sustaining FOXM1 Expression and Cell Proliferation Program | Zhang S, Zhao BS, Zhou A, Lin K, Zheng S, Lu Z, Chen Y, Sulman E, Xie K, Bogler O, Majumder S, He C, Huang S | Cancer Cell |
| 2017/4/6 | Transcription Impacts the Efficiency of mRNA Translation via Co-transcriptional N6-adenosine Methylation. | Slobodin B, Han R, Calderone V, Vrielink JA, Loayza-Puch F, Elkon R, Agami R | Cell |
| 2017/7/17 | A sensitive photoelectrochemical immunoassay of N6 - methyladenosine based on dual-signal amplification strategy: Ru doped in SiO2 nanosphere and carboxylated g-C3N4 | Haiyan Wang, Chunling Qi, Wenhuan He, Minghui Wang, Wenjing Jiang, Huanshun Yin, Shiyun Ai | Biosensors and Bioelectronics |
| 2017/6/1 | The Role of The RNA Demethylase FTO (Fat Mass and Obesity-Associated) and mRNA Methylation in Hippocampal Memory Formation. | Walters BJ, Mercaldo V, Gillon CJ, Yip M, Neve RL, Boyce FM, Frankland PW, Josselyn SA | Neuropsychopharmacology |
| 2017/5/8 | IDH Mutation, Competitive Inhibition of FTO, and RNA Methylation. | Elkashef SM, Lin AP, Myers J, Sill H, Jiang D, Dahia PLM, Aguiar RCT | Cancer Cell |
| 2016/10/4 | Hypoxia-inducible factors regulate pluripotency factor expression by ZNF217- and ALKBH5-mediated modulation of RNA methylation in breast cancer cells. | Zhang C, Zhi WI, Lu H, Samanta D, Chen I, Gabrielson E, Semenza GL | Oncotarget |
| 2017/8/18 | Reduced levels of methyltransferase DNMT2 sensitize human fibroblasts to oxidative stress and DNA damage that is accompanied by changes in proliferation-related miRNA expression. | Lewinska A, Adamczyk-Grochala J, Kwasniewicz E, Deregowska A, Semik E, Zabek T, Wnuk M | Redox Biol |
| 2021/3/1 | AMD1 upregulates hepatocellular carcinoma cells stemness by FTO mediated mRNA demethylation. | Bian X, Shi D, Xing K, Zhou H, Lu L, Yu D, Wu W | Clin Transl Med |
| 2021/3/23 | METTL3 attenuates proliferative vitreoretinopathy and epithelial-mesenchymal transition of retinal pigment epithelial cells via wnt/??-catenin pathway. | Ma X, Long C, Wang F, Lou B, Yuan M, Duan F, Yang Y, Li J, Qian X, Zeng J, Lin S, Shen H, Lin X | J Cell Mol Med |
| 2017/8/15 | Sulforaphane-Induced Cell Cycle Arrest and Senescence are accompanied by DNA Hypomethylation and Changes in microRNA Profile in Breast Cancer Cells. | Lewinska A, Adamczyk-Grochala J, Deregowska A, Wnuk M | Theranostics |
| 2021/5/1 | Role of epigenetic m<sup>6</sup> A RNA methylation in vascular development: mettl3 regulates vascular development through PHLPP2/mTOR-AKT signaling. | Parial R, Li H, Li J, Archacki S, Yang Z, Wang IZ, Chen Q, Xu C, Wang QK | FASEB J |
| 2018/1/9 | FTO regulates the chemo-radiotherapy resistance of cervical squamous cell carcinoma (CSCC) by targeting ??-catenin through mRNA demethylation. | Zhou S, Bai ZL, Xia D, Zhao ZJ, Zhao R, Wang YY, Zhe H | Mol Carcinog |
| 2018/1/31 | Increased N6-Methyladenosine causes infertility is associated with FTO expression. | Ding C, Zou Q, Ding J, Ling M, Wang W, Li H, Huang B | J Cell Physiol |
| 2018/1/1 | Curcumin Attenuates Lipopolysaccharide-Induced Hepatic Lipid Metabolism Disorder by Modification of m<sup>6</sup> A RNA Methylation in Piglets. | Lu N, Li X, Yu J, Li Y, Wang C, Zhang L, Wang T, Zhong X | Lipids |
| 2018/3/4 | METTL3 regulates alternative splicing of MyD88 upon the lipopolysaccharide-induced inflammatory response in human dental pulp cells. | Feng Z, Li Q, Meng R, Yi B, Xu Q | J Cell Mol Med |
| 2018/4/19 | N6-methyladenosine mediates the cellular proliferation and apoptosis via microRNAs in arsenite-transformed cells. | Gu S, Sun D, Dai H, Zhang Z | Toxicol Lett |
| 2018/5/18 | Analogous modified DNA probe and immune competition method-based electrochemical biosensor for RNA modification. | Dai T, Pu Q, Guo Y, Zuo C, Bai S, Yang Y, Yin D, Li Y, Sheng S, Tao Y, Fang J, Yu W, Xie G | Biosens Bioelectron |
| 2018/5/18 | Glycogen synthase kinase-3 (Gsk-3) activity regulates mRNA methylation in mouse embryonic stem cells. | Faulds KJ, Egelston JN, Sedivy LJ, Mitchell MK, Garimella S, Kozlowski H, D'Alessandro A, Hansen KC, Balsbaugh JL, Phiel CJ | J Biol Chem |
| 2018/6/6 | The regulation of skeletal muscle fiber-type composition by betaine is associated with NFATc1/MyoD. | Du J, Shen L, Zhang P, Tan Z, Cheng X, Luo J, Zhao X, Yang Q, Gu H, Jiang A, Ma J, Tang Q, Jin L, Shuai S, Li M, Jiang Y, Tang G, Bai L, Li X, Wang J, Zhang S, Zhu L | J Mol Med (Berl) |
| 2018/6/13 | Deregulation of UBE2C-mediated autophagy repression aggravates NSCLC progression. | Guo J, Wu Y, Du J, Yang L, Chen W, Gong K, Dai J, Miao S, Jin D, Xi S | Oncogenesis |
| 2018/8/14 | Sex dependent impact of gestational stress on predisposition to eating disorders and metabolic disease | Schroeder M | Molecular Metabolism |
| 2018/10/1 | Cross-talk among writers, readers, and erasers of m<sup>6</sup>A regulates cancer growth and progression. | Panneerdoss S, Eedunuri VK, Yadav P, Timilsina S, Rajamanickam S, Viswanadhapalli S, Abdelfattah N, Onyeagucha BC, Cui X, Lai Z, Mohammad TA, Gupta YK, Huang TH, Huang Y, Chen Y, Rao MK | Sci Adv |
| 2019/7/28 | The unique topologies of N6 -Adenosine methylation (m6A) in land-plant mitochondria and their putative effects on organellar gene-expression | Murik O, et. al. | bioRxiv |
| 2019/1/14 | Changes of RNA N<sup>6</sup>-methyladenosine in the hormesis effect induced by arsenite on human keratinocyte cells. | Chen H, Zhao T, Sun D, Wu M, Zhang Z | Toxicol In Vitro |
| 2019/1/19 | Reduced delivery of epididymal adipocyte-derived exosomal resistin is essential for melatonin ameliorating hepatic steatosis in mice. | Rong B, Feng R, Liu C, Wu Q, Sun C | J Pineal Res |
| 2019/3/14 | METTL3 and ALKBH5 oppositely regulate m<sup>6</sup>A modification of TFEB mRNA, which dictates the fate of hypoxia/reoxygenation-treated cardiomyocytes. | Song H, Feng X, Zhang H, Luo Y, Huang J, Lin M, Jin J, Ding X, Wu S, Huang H, Yu T, Zhang M, Hong H, Yao S, Zhao Y, Zhang Z | Autophagy |
| 2019/3/18 | Genome-wide screening of altered m6A-tagged transcript profiles in the hippocampus after traumatic brain injury in mice. | Wang Y, Mao J, Wang X, Lin Y, Hou G, Zhu J, Xie B | Epigenomics |
| 2019/3/23 | N6-Methyladenosine detected in RNA of testicular germ cell tumors is controlled by METTL3, ALKBH5, YTHDC1/F1/F2, and HNRNPC as writers, erasers, and readers. | Nettersheim D, Berger D, Jostes S, Kristiansen G, Lochnit G, Schorle H | Andrology |
| 2019/4/5 | Changes of N6-methyladenosine modulators promote breast cancer progression. | Wu L, Wu D, Ning J, Liu W, Zhang D | BMC Cancer |
| 2019/4/9 | N6-methylation of adenosine (m6A) of FZD10 mRNA contributes to PARP inhibitor resistance. | Fukumoto T, Zhu H, Nacarelli T, Karakashev S, Fatkhutdinov N, Wu S, Liu P, Kossenkov AV, Showe LC, Jean S, Zhang L, Zhang R | Cancer Res |
| 2019/3/28 | RNA N6-methyladenosine demethylase FTO promotes breast tumor progression through inhibiting BNIP3. | Niu Y, Lin Z, Wan A, Chen H, Liang H, Sun L, Wang Y, Li X, Xiong XF, Wei B, Wu X, Wan G | Mol Cancer |
| 2019/4/13 | Oxidative stress: One potential factor for arsenite-induced increase of N<sup>6</sup>-methyladenosine in human keratinocytes. | Zhao T, Li X, Sun D, Zhang Z | Environ Toxicol Pharmacol |
| 2019/4/15 | ALKBH5 inhibited autophagy of epithelial ovarian cancer through miR-7 and BCL-2. | Zhu H, Gan X, Jiang X, Diao S, Wu H, Hu J | J Exp Clin Cancer Res |
| 2019/5/1 | Transcriptome-wide map of m6A circRNAs identified in hypoxic pulmonary hypertension rat model | Su H, Zhou L, Li N, et. al. | bioRxiv |
| 2019/5/1 | Maternal heat stress regulates the early fat deposition partly through modification of m<sup>6</sup>A RNA methylation in neonatal piglets. | Heng J, Tian M, Zhang W, Chen F, Guan W, Zhang S | Cell Stress Chaperones |
| 2019/5/14 | Exposure to environmental toxicants reducesglobal N6-methyladenosine RNA methylation and alters expression of RNA methylation modulator genes | Cayir A., Barrow T., Guo L., Byun H.M. | Environmental Research |
| 2019/6/8 | METTL3 promotes experimental osteoarthritis development by regulating inflammatory response and apoptosis in chondrocyte. | Liu Q, Li M, Jiang L, Jiang R, Fu B | Biochem Biophys Res Commun |
| 2019/6/14 | Functional roles of hnRNPA2/B1 regulated by METTL3 in mammalian embryonic development. | Kwon J, Jo YJ, Namgoong S, Kim NH | Sci Rep |
| 2019/6/24 | Dysregulated N6-methyladenosine? methylation writer METTL3 contributes to the proliferation and migration of gastric cancer. | Liu T, Yang S, Sui J, Xu SY, Cheng YP, Shen B, Zhang Y, Zhang XM, Yin LH, Pu YP, Liang GY | J Cell Physiol |
| 2019/7/18 | The N6-methyladenosine mRNA methylase METTL14 promotes renal ischemic reperfusion injury via suppressing YAP1. | Xu Y, Yuan XD, Wu JJ, Chen RY, Xia L, Zhang M, Han CH, Mou S | J Cell Biochem |
| 2019/7/22 | Long non-coding RNA FAM225A promotes nasopharyngeal carcinoma tumorigenesis and metastasis by acting as ceRNA to sponge miR-590-3p/miR-1275 and upregulate ITGB3. | Zheng ZQ, Li ZX, Zhou GQ, Lin L, Zhang LL, Lv JW, Huang XD, Liu RQ, Chen F, He XJ, Kou J, Zhang J, Wen X, Li YQ, Ma J, Liu N, Sun Y | Cancer Res |
| 2019/8/13 | Evolution of the RNA N6-methyladenosine methylome mediated by genomic duplication. | Miao Z, Zhang T, Qi Y, Song J, Han Z, Ma C | Plant Physiol |
| 2019/8/24 | N6-methyladenosine METTL3 promotes the breast cancer progression via targeting Bcl-2. | Wang H, Xu B, Shi J | Gene |
| 2019/8/22 | WTAP facilitates progression of hepatocellular carcinoma via m6A-HuR-dependent epigenetic silencing of ETS1. | Chen Y, Peng C, Chen J, Chen D, Yang B, He B, Hu W, Zhang Y, Liu H, Dai L, Xie H, Zhou L, Wu J, Zheng S | Mol Cancer |
| 2019/9/13 | ALKBH overexpression in head and neck cancer: potential target for novel anticancer therapy. | Pil??ys T, Marcinkowski M, Kukwa W, Garbicz D, Dylewska M, Ferenc K, Mieczkowski A, Kukwa A, Migacz E, Wo??osz D, Mielecki D, Klungland A, Piwowarski J, Pozna??ski J, Grzesiuk E | Sci Rep |
| 2019/9/17 | N6-methyladenosine Modulates Nonsense-mediated mRNA Decay in Human Glioblastoma. | Li F, Yi Y, Miao Y, Long W, Long T, Chen S, Cheng W, Zou C, Zheng Y, Wu X, Ding J, Zhu K, Chen D, Xu Q, Wang J, Liu Q, Zhi F, Ren J, Cao Q, Zhao W | Cancer Res |
| 2019/9/24 | The RNA m6A methyltransferase METTL3 promotes pancreatic cancer cell proliferation and invasion | Xia T, Wu X, Cao M et. al. | Pathology-Research and Practice |
| 2019/10/28 | The topologies of N<sup>6</sup> -Adenosine methylation (m<sup>6</sup> A) in land plant mitochondria and their putative effects on organellar gene-expression. | Murik O, Chandran SA, Nevo-Dinur K, Sultan LD, Best C, Stein Y, Hazan C, Ostersetzer-Biran O | Plant J |
| 2019/12/9 | Electrochemical competitive immunodetection of messenger? RNA modified with N6-methyladenosine by using DNA-modified mesoporous PtCo nanospheres. | Ou X, Pu Q, Sheng S, Dai T, Gou D, Yu W, Yang T, Dai L, Yang Y, Xie G | Mikrochim Acta |
| 2020/2/6 | Bone-derived mesenchymal stem cells alleviate compression-induced apoptosis of nucleus pulposus cells by N6 methyladenosine of autophagy. | Li G, Song Y, Liao Z, Wang K, Luo R, Lu S, Zhao K, Feng X, Liang H, Ma L, Wang B, Ke W, Yin H, Zhan S, Li S, Wu X, Zhang Y, Yang C | Cell Death Dis |
| 2019/11/13 | N6-Methyladenosine RNA Methylation Regulators Contribute to Malignant Progression and Survival Prediction in Chronic Lymphocytic Leukemia | Zhang Y, et. al. | Blood |
| 2019/11/27 | Phloroglucinol Treatment Induces Transgenerational Epigenetic Inherited Resistance Against <i>Vibrio</i> Infections and Thermal Stress in a Brine Shrimp (<i>Artemia franciscana</i>) Model. | Roy S, Kumar V, Bossier P, Norouzitallab P, Vanrompay D | Front Immunol |
| 2019/9/15 | m6A demethylase FTO promotes hepatocellular carcinoma tumorigenesis via mediating PKM2 demethylation. | Li J, Zhu L, Shi Y, Liu J, Lin L, Chen X | Am J Transl Res |
| 2019/12/19 | KIAA1429 contributes to liver cancer progression through N6-methyladenosine-dependent post-transcriptional modification of GATA3. | Lan T, Li H, Zhang D, Xu L, Liu H, Hao X, Yan X, Liao H, Chen X, Xie K, Li J, Liao M, Huang J, Yuan K, Zeng Y, Wu H | Mol Cancer |
| 2020/1/7 | Mono-(2-Ethylhexyl)phthalate Regulates Cholesterol Efflux via MicroRNAs Regulated m<sup>6</sup>A RNA Methylation. | Park MH, Jeong E, Choudhury M | Chem Res Toxicol |
| 2020/1/7 | N<sup>6</sup>-methyladenosine mediates arsenite-induced human keratinocyte transformation by suppressing p53 activation. | Zhao T, Sun D, Zhao M, Lai Y, Liu Y, Zhang Z | Environ Pollut |
| 2020/1/6 | Increased m6A RNA modification is related to the inhibition of the Nrf2-mediated antioxidant response in di-(2-ethylhexyl) phthalate-induced prepubertal testicular injury. | Zhao TX, Wang JK, Shen LJ, Long CL, Liu B, Wei Y, Han LD, Wei YX, Wu SD, Wei GH | Environ Pollut |
| 2020/1/13 | Transcriptome-wide map of m<sup>6</sup>A circRNAs identified in a rat model of hypoxia mediated pulmonary hypertension. | Su H, Wang G, Wu L, Ma X, Ying K, Zhang R | BMC Genomics |
| 2020/2/4 | RNA m<sup>6</sup> A methylation regulates uveal melanoma cell proliferation, migration, and invasion by targeting c-Met. | Luo G, Xu W, Zhao Y, Jin S, Wang S, Liu Q, Chen X, Wang J, Dong F, Hu DN, Reinach PS, Yan D | J Cell Physiol |
| 2020/2/24 | Oocyte competence is maintained by m<sup>6</sup>A methyltransferase KIAA1429-mediated RNA metabolism during mouse follicular development. | Hu Y, Ouyang Z, Sui X, Qi M, Li M, He Y, Cao Y, Cao Q, Lu Q, Zhou S, Liu L, Liu L, Shen B, Shu W, Huo R | Cell Death Differ |
| 2019/12/1 | Increased m6A methylation level is associated with the progression of human abdominal aortic aneurysm. | He Y, Xing J, Wang S, Xin S, Han Y, Zhang J | Ann Transl Med |
| 2020/2/24 | MYC Regulation of D2HGDH and L2HGDH Influences the Epigenome and Epitranscriptome. | Qiu Z, Lin AP, Jiang S, Elkashef SM, Myers J, Srikantan S, Sasi B, Cao JZ, Godley LA, Rakheja D, Lyu Y, Zheng S, Madesh M, Shiio Y, Dahia PLM, Aguiar RCT | Cell Chem Biol |
| 2020/2/27 | m<sup>6</sup>A demethylase ALKBH5 inhibits tumor growth and metastasis by reducing YTHDFs-mediated YAP expression and inhibiting miR-107/LATS2-mediated YAP activity in NSCLC. | Jin D, Guo J, Wu Y, Yang L, Wang X, Du J, Dai J, Chen W, Gong K, Miao S, Li X, Sun H | Mol Cancer |
| 2020/2/20 | Hypoxia Promotes Vascular Smooth Muscle Cell (VSMC) Differentiation of Adipose-Derived Stem Cell (ADSC) by Regulating Mettl3 and Paracrine Factors | Lin J, et al. | Stem Cells International |
| 2020/2/28 | Differential mechanisms regarding triclosan vs. bisphenol A and fluorene-9-bisphenol induced zebrafish lipid-metabolism disorders by RNA-Seq | Sun L et. al. | Chemosphere |
| 2020/2/28 | N6??‘methyladenosine RNA methylation regulators participate in malignant progression and have prognostic value in clear cell renal cell carcinoma | Zheng Z et. al. | Oncolody Reports |
| 2020/2/28 | METTL3 Modulates Osteoclast Differentiation and Function by Controlling RNA Stability and Nuclear Export. | Li D, Cai L, Meng R, Feng Z, Xu Q | Int J Mol Sci |
| 2020/3/10 | SIRT1 regulates N<sup>6</sup> -methyladenosine RNA modification in hepatocarcinogenesis by inducing RANBP2-dependent FTO SUMOylation. | Liu X, Liu J, Xiao W, Zeng Q, Bo H, Zhu Y, Gong L, He D, Xing X, Li R, Zhou M, Xiong W, Zhou Y, Zhou J, Li X, Guo F, Xu C, Chen X, Wang X, Wang F, Wang Q, Cao K | Hepatology |
| 2020/4/3 | m<sup>6</sup>A-dependent glycolysis enhances colorectal cancer progression. | Shen C, Xuan B, Yan T, Ma Y, Xu P, Tian X, Zhang X, Cao Y, Ma D, Zhu X, Zhang Y, Fang JY, Chen H, Hong J | Mol Cancer |
| 2020/3/19 | Hypothermia protects neurons against ischemia/reperfusion-induced pyroptosis via m6A-mediated activation of PTEN and the PI3K/Akt/GSK-3?? signaling pathway. | Diao MY, Zhu Y, Yang J, Xi SS, Wen X, Gu Q, Hu W | Brain Res Bull |
| 2020/4/13 | Resveratrol Attenuates Aflatoxin B<sub>1</sub>-Induced ROS Formation and Increase of m<sup>6</sup>A RNA Methylation. | Wu J, Gan Z, Zhuo R, Zhang L, Wang T, Zhong X | Animals (Basel) |
| 2020/5/7 | TRIM11 facilitates chemoresistance in nasopharyngeal carcinoma by activating the ??-catenin/ABCC9 axis via p62-selective autophagic degradation of Daple. | Zhang R, Li SW, Liu L, Yang J, Huang G, Sang Y | Oncogenesis |
| 2020/5/14 | Dynamic landscape and evolution of m6A methylation in human. | Zhang H, Shi X, Huang T, Zhao X, Chen W, Gu N, Zhang R | Nucleic Acids Res |
| 2020/5/13 | m<sup>6</sup>A mRNA Methylation Controls Functional Maturation in Neonatal Murine ?? Cells. | Wang Y, Sun J, Lin Z, Zhang W, Wang S, Wang W, Wang Q, Ning G | Diabetes |
| 2020/5/8 | Leukemogenic Chromatin Alterations Promote AML Leukemia Stem Cells via a KDM4C-ALKBH5-AXL Signaling Axis. | Wang J, Li Y, Wang P, Han G, Zhang T, Chang J, Yin R, Shan Y, Wen J, Xie X, Feng M, Wang Q, Hu J, Cheng Y, Zhang T, Li Y, Gao Z, Guo C, Wang J, Liang J, Cui M, Gao K, Chai J, Liu W, Cheng H, Li L, Zhou F, Liu L, Luo Y, Li S, Zhang H | Cell Stem Cell |
| 2020/5/15 | N6-methyladenosine methyltransferase METTL3 promotes colorectal cancer cell proliferation through enhancing MYC expression. | Xiang S, Liang X, Yin S, Liu J, Xiang Z | Am J Transl Res |
| 2020/5/21 | LncRNA SOX2OT promotes temozolomide resistance by elevating SOX2 expression via ALKBH5-mediated epigenetic regulation in glioblastoma. | Liu B, Zhou J, Wang C, Chi Y, Wei Q, Fu Z, Lian C, Huang Q, Liao C, Yang Z, Zeng H, Xu N, Guo H | Cell Death Dis |
| 2020/5/25 | Fat mass and obesity-associated protein promotes the tumorigenesis and development of liver cancer | Ye, Z et. al. | Oncology Letters |
| 2020/5/1 | Dendritic cells with METTL3 gene knockdown exhibit immature properties and prolong allograft survival. | Wu H, Xu Z, Wang Z, Ren Z, Li L, Ruan Y | Genes Immun |
| 2020/6/16 | m<sup>6</sup>A Modification Prevents Formation of Endogenous Double-Stranded RNAs and Deleterious Innate Immune Responses during Hematopoietic Development. | Gao Y, Vasic R, Song Y, Teng R, Liu C, Gbyli R, Biancon G, Nelakanti R, Lobben K, Kudo E, Liu W, Ardasheva A, Fu X, Wang X, Joshi P, Lee V, Dura B, Viero G, Iwasaki A, Fan R, Xiao A, Flavell RA, Li HB, Tebaldi T, Halene S | Immunity |
| 2020/6/16 | Alteration of N<sup>6</sup>-methyladenosine epitranscriptome profile in unilateral ureteral obstructive nephropathy. | Li X, Fan X, Yin X, Liu H, Yang Y | Epigenomics |
| 2020/6/16 | N6-methyladenosine regulates PEDV replication and host gene expression | Chen, J et. al. | Virology |
| 2020/6/29 | Programmable m<sup>6</sup>A modification of cellular RNAs with a Cas13-directed methyltransferase. | Wilson C, Chen PJ, Miao Z, Liu DR | Nat Biotechnol |
| 2020/6/30 | FTO-Dependent N6-Methyladenosine Modifications Inhibit Ovarian Cancer Stem Cell Self-Renewal by Blocking cAMP Signaling. | Huang H, Wang Y, Kandpal M, Zhao G, Cardenas H, Ji Y, Chaparala A, Tanner EJ, Chen J, Davuluri RV, Matei D | Cancer Res |
| 2020/6/26 | m6A methyltransferase METTL3 maintains colon cancer tumorigenicity by suppressing SOCS2 to promote cell proliferation | Xu, J Et. al. | Oncology Reports |
| 2020/7/2 | The m6A Methylation-Regulated AFF4 Promotes Self-Renewal of Bladder Cancer Stem Cells | Gao, Q et. al. | Stem Cells Int |
| 2020/7/13 | Dexmedetomidine Suppressed the Biological Behavior of HK-2 Cells Treated with LPS by Down-Regulating ALKBH5. | Zhu S, Lu Y | Inflammation |
| 2020/9/10 | RNA N6-methyladenosine demethylase FTO regulates PD-L1 expression in colon cancer cells | Tsuruta K. et. al. | Biochemical and Biophysical Research Communications |
| 2020/8/9 | Pregnancy carbon black nanoparticles exposure-induced neurobehavioral deficits are associated with m6A modification in offspring. | Zhang S, Meng P, Cheng S, Jiang X, Zhang J, Qin X, Tang Q, Bai L, Zou Z, Chen C | Neurotoxicology |
| 2020/7/11 | METTL14 aggravates endothelial inflammation and atherosclerosis by increasing FOXO1 N6-methyladeosine modifications. | Jian D, Wang Y, Jian L, Tang H, Rao L, Chen K, Jia Z, Zhang W, Liu Y, Chen X, Shen X, Gao C, Wang S, Li M | Theranostics |
| 2020/8/17 | The FTO/miR-181b-3p/ARL5B signaling pathway regulates cell migration and invasion in breast cancer. | Xu Y, Ye S, Zhang N, Zheng S, Liu H, Zhou K, Wang L, Cao Y, Sun P, Wang T | Cancer Commun (Lond) |
| 2020/8/13 | N 6-Adenosine Methylation of Socs1 mRNA is Required to Sustain the Negative Feedback Control of Macrophage Activation | Du J. et. al. | Developmental Cell |
| 2020/8/2 | RNA N6-Methyladenosine Reader IGF2BP3 Regulates Cell Cycle and Angiogenesis in Colon Cancer | Yang Z. et. al. | General Surgery |
| 2020/8/19 | WTAP promotes osteosarcoma tumorigenesis by repressing HMBOX1 expression in an m<sup>6</sup>A-dependent manner. | Chen S, Li Y, Zhi S, Ding Z, Wang W, Peng Y, Huang Y, Zheng R, Yu H, Wang J, Hu M, Miao J, Li J | Cell Death Dis |
| 2020/8/25 | Upregulation of METTL14 mediates the elevation of PERP mRNA N 6 adenosine methylation promoting the growth and metastasis of pancreatic cancer | Wang M. et al. | Mol Cancer |
| 2020/8/20 | Decreased ALKBH5, FTO, and YTHDF2 in Peripheral Blood Are as Risk Factors for Rheumatoid Arthritis | Luo Q et. al. | Biomed Res Int |
| 2020/8/28 | METTL3 potentiates resistance to cisplatin through m<sup>6</sup> A modification of TFAP2C in seminoma. | Wei J, Yin Y, Zhou J, Chen H, Peng J, Yang J, Tang Y | J Cell Mol Med |
| 2020/9/1 | Altered m<sup>6</sup> A modification is involved in up-regulated expression of FOXO3 in luteinized granulosa cells of non-obese polycystic ovary syndrome patients. | Zhang S, Deng W, Liu Q, Wang P, Yang W, Ni W | J Cell Mol Med |
| 2020/9/6 | m<sup>6</sup> A transferase METTL3-induced lncRNA ABHD11-AS1 promotes the Warburg effect of non-small-cell lung cancer. | Xue L, Li J, Lin Y, Liu D, Yang Q, Jian J, Peng J | J Cell Physiol |
| 2020/10/7 | Integrated Study of Transcriptome-wide m6A Methylome Confirms a Potential Mechanism for Transcriptional Regulation During Yak Adipocytes Differentiation | Zhang Y et al. | BMC Genomics |
| 2020/8/15 | ALKBH5 promotes colon cancer progression by decreasing methylation of the lncRNA NEAT1. | Guo T, Liu DF, Peng SH, Xu AM | Am J Transl Res |
| 2020/10/8 | Magnetic microbeads-based amperometric immunoplatform for the rapid and sensitive detection of N6-methyladenosine to assist in metastatic cancer cells discrimination. | Povedano E, Gamella M, Torrente-Rodr??guez RM, Montero-Calle A, Pedrero M, Sol??s-Fern??ndez G, Navarro-Villoslada F, Barderas R, Campuzano S, Pingarr??n JM | Biosens Bioelectron |
| 2020/10/13 | Upregulation of METTL3 expression and m6A RNA methylation in placental trophoblasts in preeclampsia. | Gu Y, Chu X, Morgan JA, Lewis DF, Wang Y | Placenta |
| 2020/11/12 | KIAA1429 promotes the progression of lung adenocarcinoma by regulating the m6A level of MUC3A | Zhao W. et. al. | Pathology-Research and Practice |
| 2020/11/7 | N6-methyladenosine RNA methylation regulators contribute to the progression of prostate cancer | Wu Q. et. al. | Journal of Cancer |
| 2020/11/11 | Long non-coding RNA IGF2-AS represses breast cancer tumorigenesis by epigenetically regulating IGF2. | Zhang Y, Yan H, Jiang Y, Chen T, Ma Z, Li F, Lin M, Xu Y, Zhang X, Zhang J, He H | Exp Biol Med (Maywood) |
| 2020/11/11 | The mechanism of m<sup>6</sup>A methyltransferase METTL3-mediated autophagy in reversing gefitinib resistance in NSCLC cells by ??-elemene. | Liu S, Li Q, Li G, Zhang Q, Zhuo L, Han X, Zhang M, Chen X, Pan T, Yan L, Jin T, Wang J, Lv Q, Sui X, Xie T | Cell Death Dis |
| 2020/11/4 | DNA methylation of FTO promotes renal inflammation by enhancing m<sup>6</sup>A of PPAR-?± in alcohol-induced kidney injury. | Yu JT, Hu XW, Chen HY, Yang Q, Li HD, Dong YH, Zhang Y, Wang JN, Jin J, Wu YG, Li J, Ge JF, Meng XM | Pharmacol Res |
| 2020/10/27 | Upregulated N6-methyladenosine RNA in Peripheral Blood: Potential Diagnostic Biomarker for Breast Cancer. | Xiao H, Fan X, Zhang R, Wu G | Cancer Res Treat |
| 2020/10/16 | YTHDF3 Induces the Translation of m<sup>6</sup>A-Enriched Gene Transcripts to Promote Breast Cancer Brain Metastasis. | Chang G, Shi L, Ye Y, Shi H, Zeng L, Tiwary S, Huse JT, Huo L, Ma L, Ma Y, Zhang S, Zhu J, Xie V, Li P, Han L, He C, Huang S | Cancer Cell |
| 2020/10/23 | METTL3 promotes IL-1??-induced degeneration of endplate chondrocytes by driving m6A-dependent maturation of miR-126-5p. | Xiao L, Zhao Q, Hu B, Wang J, Liu C, Xu H | J Cell Mol Med |
| 2020/10/20 | Fat mass and obesity-associated protein regulates lipogenesis via m<sup>6</sup> A modification in fatty acid synthase mRNA. | Sun D, Zhao T, Zhang Q, Wu M, Zhang Z | Cell Biol Int |
| 2020/11/18 | LKB1 Loss Upregulates ALKBH5 and Contributes to Aggressive Phenotypes of KRAS Mutated Lung Cancer | Zhang, D et. al. | Research Square |
| 2020/11/17 | N6-methyladenosine methyltransferase plays a role in hypoxic preconditioning partially through the interaction with lncRNA H19. | Su Y, Xu R, Zhang R, Qu Y, Zuo W, Ji Z, Geng H, Pan M, Ma G | Acta Biochim Biophys Sin (Shanghai) |
| 2020/10/26 | YTHDF1-enhanced iron metabolism depends on TFRC m<sup>6</sup>A methylation. | Ye J, Wang Z, Chen X, Jiang X, Dong Z, Hu S, Li W, Liu Y, Liao B, Han W, Shen J, Xiao M | Theranostics |
| 2020/11/19 | Stabilization of ERK-Phosphorylated METTL3 by USP5 Increases m<sup>6</sup>A Methylation. | Sun HL, Zhu AC, Gao Y, Terajima H, Fei Q, Liu S, Zhang L, Zhang Z, Harada BT, He YY, Bissonnette MB, Hung MC, He C | Mol Cell |
| 2020/11/22 | Decreased expression of m<sup>6</sup>A demethylase FTO in ovarian aging. | Sun X, Zhang Y, Hu Y, An J, Li L, Wang Y, Zhang X | Arch Gynecol Obstet |
| 2020/11/29 | The effects of folic acid on RNA m6A methylation in hippocampus as well as learning and memory ability of rats with acute lead exposure | Li N. et. al. | Journal of Functional Foods |
| 2020/12/1 | The critical role of m6A methylation in the pathogenesis of Graves' ophthalmopathy | Zhu L. et. al. | Eye and Vision |
| 2020/12/4 | Resveratrol Supplementation Attenuates Cognitive and Molecular Alterations Under Maternal High-Fat Diet Intake: Multigenerational Epigenetic Inheritance. | Izquierdo, V. et. al. | Preprints |
| 2020/12/1 | Novel Prognostic Implications of Methylated RNA and Demethylases in Resected HCC and Background Liver Tissue. | Nakagawa N, Tanaka K, Sonohara F, Kandimalla R, Sunagawa Y, Inokawa Y, Takami H, Hayashi M, Yamada S, Kanda M, Tanaka C, Nakayama G, Koike M, Kodera Y | Anticancer Res |
| 2021/1/1 | N<sup>6</sup>-methyladenosine (m<sup>6</sup>A) methyltransferase WTAP accelerates the Warburg effect of gastric cancer through regulating HK2 stability. | Yu H, Zhao K, Zeng H, Li Z, Chen K, Zhang Z, Li E, Wu Z | Biomed Pharmacother |
| 2019/5/31 | The m6A demethylase ALKBH5 controls trophoblast invasion at the maternal-fetal interface by regulating the stability of <i>CYR61</i> mRNA. | Li XC, Jin F, Wang BY, Yin XJ, Hong W, Tian FJ | Theranostics |
| 2020/12/23 | miR-338-5p inhibits cell growth and migration via inhibition of the METTL3/m6A/c-Myc pathway in lung cancer. | Wu H, Li F, Zhu R | Acta Biochim Biophys Sin (Shanghai) |
| 2021/2/1 | Transcriptomics and flow cytometry reveals the cytotoxicity of aflatoxin B<sub>1</sub> and aflatoxin M<sub>1</sub> in bovine mammary epithelial cells. | Wu K, Jia S, Zhang J, Zhang C, Wang S, Rajput SA, Sun L, Qi D | Ecotoxicol Environ Saf |
| 2021/1/4 | METTL14-regulated PI3K/Akt signaling pathway via PTEN affects HDAC5-mediated epithelial-mesenchymal transition of renal tubular cells in diabetic kidney disease. | Xu Z, Jia K, Wang H, Gao F, Zhao S, Li F, Hao J | Cell Death Dis |
| 2020/12/31 | The Role of RNA m6A Methylation in the Regulation of Postnatal Hypoxia-induced Pulmonary Hypertension | Xu S. et. al. | Respiratory Research BMC |
| 2021/1/22 | Triclosan-induced abnormal expression of miR-30b regulates fto-mediated m<sup>6</sup>A methylation level to cause lipid metabolism disorder in zebrafish. | Sun L, Gao M, Qian Q, Guo Z, Zhu P, Wang X, Wang H | Sci Total Environ |
| 2021/1/21 | METTL3 restrains papillary thyroid cancer progression via m<sup>6</sup>A/c-Rel/IL-8-mediated neutrophil infiltration. | He J, Zhou M, Yin J, Wan J, Chu J, Jia J, Sheng J, Wang C, Yin H, He F | Mol Ther |
| 2021/2/1 | Resveratrol Supplementation Attenuates Cognitive and Molecular Alterations under Maternal High-Fat Diet Intake: Epigenetic Inheritance over Generations. | Izquierdo V, Palomera-??valos V, Pall? s M, Gri?±??n-Ferr?? C | Int J Mol Sci |
| 2021/2/6 | FTO overexpression inhibits apoptosis of hypoxia/reoxygenation-treated myocardial cells by regulating m6A modification of Mhrt. | Shen W, Li H, Su H, Chen K, Yan J | Mol Cell Biochem |
| 2021/3/2 | RNA m6A methylation orchestrates cancer growth and metastasis via macrophage reprogramming. | Yin H, Zhang X, Yang P, Zhang X, Peng Y, Li D, Yu Y, Wu Y, Wang Y, Zhang J, Ding X, Wang X, Yang A, Zhang R | Nat Commun |
| 2021/3/2 | m6A mRNA methylation regulates the development of gestational diabetes mellitus in Han Chinese women. | Wang J, Wang K, Liu W, Cai Y, Jin H | Genomics |
| 2021/2/27 | FTO regulates myoblast proliferation by controlling CCND1 expression in an m<sup>6</sup>A-YTHDF2-dependent manner. | Deng K, Zhang Z, Ren C, Liang Y, Gao X, Fan Y, Wang F | Exp Cell Res |
| 2021/5/5 | m<sup>6</sup>A demethylase ALKBH5 suppresses proliferation and migration of enteric neural crest cells by regulating TAGLN in Hirschsprung's disease. | Wang B, Fang X, Sun X, Du C, Zhou L, Lv X, Li Y, Li H, Tang W | Life Sci |
| 2021/5/4 | N6-methyladenosine demethylase FTO impairs hepatic ischemia-reperfusion injury via inhibiting Drp1-mediated mitochondrial fragmentation. | Du YD, Guo WY, Han CH, Wang Y, Chen XS, Li DW, Liu JL, Zhang M, Zhu N, Wang X | Cell Death Dis |
| 2021/4/26 | Small-Molecule Inhibitors of the RNA M6A Demethylases FTO Potently Support the Survival of Dopamine Neurons. | Selberg S, Yu LY, Bondarenko O, Kankuri E, Seli N, Kovaleva V, Herodes K, Saarma M, Karelson M | Int J Mol Sci |
| 2021/2/24 | Changes and relationship of N<sup>6</sup>-methyladenosine modification and long non-coding RNAs in oxidative damage induced by cadmium in pancreatic ??-cells. | Qu T, Mou Y, Dai J, Zhang X, Li M, Gu S, He Z | Toxicol Lett |
| 2021/2/9 | HOXA10 mediates epithelial-mesenchymal transition to promote gastric cancer metastasis partly via modulation of TGFB2/Smad/METTL3 signaling axis. | Song C, Zhou C | J Exp Clin Cancer Res |
| 2021/2/23 | Clinical significance and potential mechanisms of the RNA methyltransferase KIAA1429 in osteosarcoma | Sun Y. et. al. | BMC Cancer |
| 2021/3/11 | Mettl14-mediated m6A modification modulates neuron apoptosis during the repair of spinal cord injury by regulating the transformation from pri-mir-375 to miR-375. | Wang H, Yuan J, Dang X, Shi Z, Ban W, Ma D | Cell Biosci |
| 2021/3/16 | The m<sup>6</sup>A methyltransferase METTL3 promotes hypoxic pulmonary arterial hypertension. | Qin Y, Qiao Y, Li L, Luo E, Wang D, Yao Y, Tang C, Yan G | Life Sci |
| 2021/3/16 | Identification of an N6-methyladenosine-mediated positive feedback loop that promotes Epstein-Barr virus infection. | Dai DL, Li X, Wang L, Xie C, Jin Y, Zeng MS, Zuo Z, Xia TL | J Biol Chem |
| 2021/4/9 | A methionine-Mettl3-N<sup>6</sup>-methyladenosine axis promotes polycystic kidney disease. | Ramalingam H, Kashyap S, Cobo-Stark P, Flaten A, Chang CM, Hajarnis S, Hein KZ, Lika J, Warner GM, Espindola-Netto JM, Kumar A, Kanchwala M, Xing C, Chini EN, Patel V | Cell Metab |
| 2021/4/20 | Transcriptome-wide N6-methyladenosine methylation landscape of coronary artery disease. | Deng K, Ning X, Ren X, Yang B, Li J, Cao J, Chen J, Lu X, Chen S, Wang L | Epigenomics |
| 2021/5/1 | ALKBH5-mediated m6A demethylation of lncRNA RMRP plays an oncogenic role in lung adenocarcinoma. | Yu H, Zhang Z | Mamm Genome |
| 2021/4/1 | The m6A methyltransferase METTL3 regulates autophagy and sensitivity to cisplatin by targeting ATG5 in seminoma. | Chen H, Xiang Y, Yin Y, Peng J, Peng D, Li D, Kitazawa R, Tang Y, Yang J | Transl Androl Urol |
| 2021/5/8 | Enhanced antioxidant capacity prevents epitranscriptomic and cardiac alterations in adult offspring gestationally-exposed to ENM. | Kunovac A, Hathaway QA, Pinti MV, Durr AJ, Taylor AD, Goldsmith WT, Garner KL, Nurkiewicz TR, Hollander JM | Nanotoxicology |
| 2021/4/26 | The role of RNA m<sup>6</sup>A methylation in the regulation of postnatal hypoxia-induced pulmonary hypertension. | Xu S, Xu X, Zhang Z, Yan L, Zhang L, Du L | Respir Res |
| 2021/5/18 | ALKBH1-demethylated DNA N6-methyladenine modification triggers vascular calcification via osteogenic reprogramming in chronic kidney disease. | Ouyang L, Su X, Li W, Tang L, Zhang M, Zhu Y, Xie C, Zhang P, Chen J, Huang H | J Clin Invest |
| 2021/5/20 | Suppression of m6A mRNA modification by DNA hypermethylated ALKBH5 aggravates the oncological behavior of KRAS mutation/LKB1 loss lung cancer. | Zhang D, Ning J, Okon I, Zheng X, Satyanarayana G, Song P, Xu S, Zou MH | Cell Death Dis |
| 2021/5/21 | Apostichopus japonicus Oligopeptide Induced Heterogeneity in the Gastrointestinal Tract Microbiota and Alleviated Hyperuricemia in a Microbiota-Dependent Manner. | Lu C, Tang S, Han J, Fan S, Huang Y, Zhang Z, Zhou J, Ming T, Li Y, Su X | Mol Nutr Food Res |
| 2021/5/14 | Rational Design of Novel Anticancer Small-Molecule RNA m6A Demethylase ALKBH5 Inhibitors | Selberg S et. al. | ACS Omega |
| 2021/6/2 | METTL16 promotes cell proliferation by up-regulating cyclin D1 expression in gastric cancer. | Wang XK, Zhang YW, Wang CM, Li B, Zhang TZ, Zhou WJ, Cheng LJ, Huo MY, Zhang CH, He YL | J Cell Mol Med |
| 2021/6/21 | METTL3 promotes tumour development by decreasing APC expression mediated by APC mRNA N<sup>6</sup>-methyladenosine-dependent YTHDF binding. | Wang W, Shao F, Yang X, Wang J, Zhu R, Yang Y, Zhao G, Guo D, Sun Y, Wang J, Xue Q, Gao S, Gao Y, He J, Lu Z | Nat Commun |
| 2021/6/21 | Long Noncoding RNA SNHG4 Remits Lipopolysaccharide???Engendered Inflammatory Lung Damage by Inhibiting METTL3 - Mediated m6A Level of STAT2 mRNA | Li S, Yan W, Liu J, Zhao Y, Chen L | Research Square |
| 2021/6/24 | FTO-mediated demethylation of GADD45B promotes myogenesis through the activation of p38 MAPK pathway | Deng, K. et. al. | Molecular Therapy - Nucleic Acids |
| 2021/6/15 | The m6A Demethylase FTO Promotes Esophageal Cancer Progression Through YTHDF1-Dependent Posttranscriptional Silencing of AKT3. | Zang C, Zhao F, Huang D, et al. | Research Square |
| 2021/6/21 | METTL3 promotes tumour development by decreasing APC expression mediated by APC mRNA N<sup>6</sup>-methyladenosine-dependent YTHDF binding. | Wang W, Shao F, Yang X, Wang J, Zhu R, Yang Y, Zhao G, Guo D, Sun Y, Wang J, Xue Q, Gao S, Gao Y, He J, Lu Z | Nat Commun |
| 2021/6/26 | Intra-arterial infusion chemotherapy utilizing cisplatin inhibits bladder cancer by decreasing the ???brocytic myeloid-derived suppressor cells in an m6A-dependent manner. | Mu X, Wu K, Zhu Y, Zhu Y, Wang Y, Xiao L, Yao Z, Huang W, Sun F, Fan J, Zheng Z, Liu Z | Mol Immunol |
| 2021/7/1 | FTO inhibits UPR<sup>mt</sup>-induced apoptosis by activating JAK2/STAT3 pathway and reducing m6A level in adipocytes. | Shen Z, Liu P, Sun Q, Li Y, Acharya R, Li X, Sun C | Apoptosis |
| 2020/10/20 | Integrated Study of Transcriptome-wide m6A Methylome Confirms a Potential Mechanism for Transcriptional Regulation During Yak Adipocytes Differentiation | Zhang, Y et. al. | Research Square |
| 2021/6/26 | m6A modification promotes miR-133a repression during cardiac development and hypertrophy via IGF2BP2. | Qian B, Wang P, Zhang D, Wu L | Cell Death Discov |
| 2021/7/13 | HNRNPC impedes m6A-dependent anti-metastatic alternative splicing events in pancreatic ductal adenocarcinoma | Huang, X.T., et. al. | Cancer Letters |
| 2021/7/12 | RNA N6-methyladenosine modification suppresses replication of rice black streaked dwarf virus and is associated with virus persistence in its insect vector. | Tian S, Wu N, Zhang L, Wang X | Mol Plant Pathol |
| 2021/7/6 | m6A mRNA Methylation Regulates Epithelial Innate Antimicrobial Defense Against Cryptosporidial Infection | Xia, Z. et. al. | Front. Immunol |
| 2021/7/13 | HNRNPC impedes m<sup>6</sup>A-dependent anti-metastatic alternative splicing events in pancreatic ductal adenocarcinoma. | Huang XT, Li JH, Zhu XX, Huang CS, Gao ZX, Xu QC, Zhao W, Yin XY | Cancer Lett |
| 2021/7/17 | IDH2 contributes to tumorigenesis and poor prognosis by regulating m6A RNA methylation in multiple myeloma. | Song S, Fan G, Li Q, Su Q, Zhang X, Xue X, Wang Z, Qian C, Jin Z, Li B, Zhuang W | Oncogene |
| 2021/7/14 | m6A methyltransferase METTL3-mediated lncRNA FOXD2-AS1 promotes the tumorigenesis of cervical cancer | Ji, F. et. al. | Molecular Therapy: Oncolytics |
| 2021/7/22 | Vitamin B<sub>12</sub> Deficiency Dysregulates m6A mRNA Methylation of Genes Involved in Neurological Functions. | Mosca P, Robert A, Alberto JM, Meyer M, Kundu U, Hergalant S, Umoret R, Coelho D, Gu??ant JL, Leheup B, Dreumont N | Mol Nutr Food Res |
| 2021/7/23 | RBM15-mediated N6-methyladenosine modification affects COVID-19 severity by regulating the expression of multitarget genes. | Meng Y, Zhang Q, Wang K, Zhang X, Yang R, Bi K, Chen W, Diao H | Cell Death Dis |
| 2021/7/26 | ALKBH10B, an m<sup>6</sup> A mRNA demethylase, plays a role in salt stress and ABA responses in Arabidopsis thaliana. | Shoaib Y, Hu J, Manduzio S, Kang H | Physiol Plant |
| 2021/7/26 | C5aR1-positive neutrophils promote breast cancer glycolysis through WTAP-dependent m6A methylation of ENO1. | Ou B, Liu Y, Yang X, Xu X, Yan Y, Zhang J | Cell Death Dis |
| 2021/7/19 | Protective role of mRNA demethylase FTO on axon guiding molecules of nigro-striatal projection system in manganese-induced Parkinsonism | Qi, Z. et. al. | Research Square |
| 2021/6/11 | Silencing of METTL3 effectively hinders invasion and metastasis of prostate cancer cells. | Chen Y, Pan C, Wang X, Xu D, Ma Y, Hu J, Chen P, Xiang Z, Rao Q, Han X | Theranostics |
| 2021/7/28 | M6A associated TSUC7 inhibition contributed to Erlotinib Resistance in Lung Adenocarcinoma through a Notch Signaling Activation Dependent Way | Li, K. et. al. | Research Square |
| 2021/8/4 | m6A Methyltransferase 3 Promotes the Proliferation and Migration of Gastric Cancer Cells through the m6A Modification of YAP1. | Zhou W, Xian Q, Wang Q, Wu C, Yan H, Li X, Lu L, Wu C, Zhu D, Xu X, Wu J | J Oncol |
| 2021/7/12 | End-labeling-based electrochemical strategy for detection of adenine methylation in nucleic acid by differential pulse voltammetry. | Yang H, Wang Y, Tang J, Wang F, Chen Z | Mikrochim Acta |
| 2021/8/5 | Cardiac-specific loss of METTL14 ameliorates cardiac hypertrophy by suppressingTLR4-mediated inflammation and oxidative stress | Xie, H. et. al. | Biochemical and Biophysical Research Communications |
| 2021/5/28 | Transcriptome and N6-Methyladenosine RNA Methylome Analyses in Aortic Dissection and Normal Human Aorta. | Zhou X, Chen Z, Zhou J, Liu Y, Fan R, Sun T | Front Cardiovasc Med |
| 2021/8/12 | Inhibition of METTL3/m6A/miR126 promotes the migration and invasion of endometrial stromal cells in endometriosis. | Li X, Xiong W, Long X, Dai X, Peng Y, Xu Y, Zhang Z, Zhang L, Liu Y | Biol Reprod |
| 2021/8/14 | IGF2BP2-modified circular RNA circARHGAP12 promotes cervical cancer progression by interacting m<sup>6</sup>A/FOXM1 manner. | Ji F, Lu Y, Chen S, Yu Y, Lin X, Zhu Y, Luo X | Cell Death Discov |
| 2021/5/28 | Transcriptome and N6-Methyladenosine RNA Methylome Analyses in Aortic Dissection and Normal Human Aorta. | Zhou X, Chen Z, Zhou J, Liu Y, Fan R, Sun T | Front Cardiovasc Med |
| 2021/8/11 | WTAP-mediated GPX4 m6A methylation triggers PASMCs ferroptosis and pulmonary vascular fibrosis in pulmonary artery hypertension | Xin, W. et. al. | Authorea |
| 2021/8/24 | METTL3 Intensifies the Progress of Oral Squamous Cell Carcinoma via Modulating the m6A Amount of PRMT5 and PD-L1 | Ai, Y. et. al. | Journal of Immunology Research |
| 2021/8/27 | OsEDM2L mediates m<sup>6</sup> A of EAT1 transcript for proper alternative splicing and polyadenylation regulating rice tapetal degradation. | Ma K, Han J, Zhang Z, Li H, Zhao Y, Zhu Q, Xie Y, Liu YG, Chen L | J Integr Plant Biol |
| 2021/8/20 | Interaction of tau with HNRNPA2B1 and N<sup>6</sup>-methyladenosine RNA mediates the progression of tauopathy. | Jiang L, Lin W, Zhang C, Ash PEA, Verma M, Kwan J, van Vliet E, Yang Z, Cruz AL, Boudeau S, Maziuk BF, Lei S, Song J, Alvarez VE, Hovde S, Abisambra JF, Kuo MH, Kanaan N, Murray ME, Crary JF, Zhao J, Cheng JX, Petrucelli L, Li H, Emili A, Wolozin B | Mol Cell |
| 2021/9/1 | Degradation of WTAP blocks antiviral responses by reducing the m<sup>6</sup> A levels of IRF3 and IFNAR1 mRNA. | Ge Y, Ling T, Wang Y, Jia X, Xie X, Chen R, Chen S, Yuan S, Xu A | EMBO Rep |
| 2021/9/7 | Streptozotocin-Induced Astrocyte Mitochondrial Dysfunction Is Ameliorated by FTO Inhibitor MO-I-500. | Cockova Z, Honc O, Telensky P, Olsen MJ, Novotny J | ACS Chem Neurosci |
| 2021/9/7 | METTL3-mediated RNA m6A hypermethylation promotes tumorigenesis and GH secretion of pituitary somatotroph adenomas. | Chang M, Wang Z, Gao J, Yang C, Feng M, Niu Y, Tong WM, Bao X, Wang R | J Clin Endocrinol Metab |
| 2021/9/10 | METTL3-Mediated lncRNA m<sup>6</sup>A Modification in the Osteogenic Differentiation of Human Adipose-Derived Stem Cells Induced by NEL-Like 1 Protein. | Song Y, Pan Y, Wu M, Sun W, Luo L, Zhao Z, Liu J | Stem Cell Rev Rep |
| 2021/9/1 | Transcriptome-wide m<sup>6</sup>A methylome during osteogenic differentiation of human adipose-derived stem cells. | Sun W, Song Y, Xia K, Yu L, Huang X, Zhao Z, Liu J | Stem Cell Res Ther |
| 2021/8/30 | IGF2BP2 Promotes Pancreatic Carcinoma Progression by Enhancing the Stability of B3GNT6 mRNA via m6A Methylation | Xue, X. et. al. | Research Square |
| 2021/8/31 | ebv-circRPMS1 Promotes the Progression of EBV-Associated Gastric Carcinoma via Sam68 Complex Dependent Activation of METTL3 | Zhang, J. et. al. | Research Square |
| 2021/9/11 | DNAzyme based three-way junction assay for antibody-free detection of locus-specific N6-methyladenosine modifications | Yu, H. et. al. | Biosensors and Bioelectronics |
| 2021/9/21 | METTL3-mediated M6A methylation modification is involved in colistin-induced nephrotoxicity through apoptosis mediated by Keap1/Nrf2 signaling pathway. | Xia C, Wang J, Wu Z, Miao Y, Chen C, Li R, Li J, Xing H | Toxicology |
| 2021/9/25 | METTL3-Induced miR-222-3p Upregulation Inhibits STK4 and Promotes the Malignant Behaviors of Thyroid Carcinoma Cells. | Lin S, Zhu Y, Ji C, Yu W, Zhang C, Tan L, Long M, Luo D, Peng X | J Clin Endocrinol Metab |
| 2021/9/22 | m6A Demethylase FTO Promotes Tumor Progression via Regulation of Lipid Metabolism in Esophageal Cancer | Duan, X. et. al. | Research Square |
| 2021/9/17 | METTL3-mediated m<sup>6</sup>A RNA methylation promotes the anti-tumour immunity of natural killer cells. | Song H, Song J, Cheng M, Zheng M, Wang T, Tian S, Flavell RA, Zhu S, Li HB, Ding C, Wei H, Sun R, Peng H, Tian Z | Nat Commun |
| 2021/9/28 | Increased m6A-RNA methylation and FTO suppression is associated with myocardial inflammation and dysfunction during endotoxemia in mice. | Dubey PK, Patil M, Singh S, Dubey S, Ahuja P, Verma SK, Krishnamurthy P | Mol Cell Biochem |
| 2021/9/27 | METTL14 aggravates podocyte injury and glomerulopathy progression through N<sup>6</sup>-methyladenosine-dependent downregulating of Sirt1. | Lu Z, Liu H, Song N, Liang Y, Zhu J, Chen J, Ning Y, Hu J, Fang Y, Teng J, Zou J, Dai Y, Ding X | Cell Death Dis |
| 2021/9/26 | N<sup>6</sup>-methyladenosine modification regulates ferroptosis through autophagy signaling pathway in hepatic stellate cells. | Shen M, Li Y, Wang Y, Shao J, Zhang F, Yin G, Chen A, Zhang Z, Zheng S | Redox Biol |
| 2021/5/25 | Rational Design of Novel Anticancer Small-Molecule RNA m6A Demethylase ALKBH5 Inhibitors. | Selberg S, Seli N, Kankuri E, Karelson M | ACS Omega |
| 2021/10/4 | Engineered pegRNAs improve prime editing efficiency. | Nelson JW, Randolph PB, Shen SP, Everette KA, Chen PJ, Anzalone AV, An M, Newby GA, Chen JC, Hsu A, Liu DR | Nat Biotechnol |
| 2021/10/13 | Overexpression of watermelon m6A methyltransferase ClMTB enhances drought tolerance in tobacco by mitigating oxidative stress and photosynthesis inhibition and modulating stress-responsive gene expression | He, Y. et. al. | Plant Physiology and Biochemistry |
| 2021/10/13 | Differential m<sup>6</sup>A RNA landscapes across hematopoiesis reveal a role for IGF2BP2 in preserving hematopoietic stem cell function. | Yin R, Chang J, Li Y, Gao Z, Qiu Q, Wang Q, Han G, Chai J, Feng M, Wang P, Zhang T, Xie X, Hu J, Cheng Y, Guo C, Wang J, Gao K, Cui M, Li S, Zheng Y, Jiang W, Hu Y, Yang QY, Zhang H | Cell Stem Cell |
| 2021/10/25 | HOTAIR/Sp1/miR-199a critically regulates cancer stemness and malignant progression of cutaneous squamous cell carcinoma. | Chen J, Hou SF, Tang FJ, Liu DS, Chen ZZ, Zhang HL, Wang SH | Oncogene |
| 2021/11/1 | FTO promotes tumour proliferation in bladder cancer via the FTO/miR-576/CDK6 axis in an m6A-dependent manner. | Zhou G, Yan K, Liu J, Gao L, Jiang X, Fan Y | Cell Death Discov |
| 2021/11/2 | Involvement of METTL3/m<sup>6</sup>Adenosine and TGF??/Smad3 signaling on Tenon's fibroblasts and in a rabbit model of glaucoma surgery. | Liu Y, Gu C, Li X, Wang T, Yu L | J Mol Histol |
| 2021/11/8 | Transcriptome-wide N6-methyladenosine (m<sup>6</sup>A) methylation in watermelon under CGMMV infection. | He Y, Li L, Yao Y, Li Y, Zhang H, Fan M | BMC Plant Biol |
| 2021/11/10 | METTL3 Depletion Contributes to HR+/HER2- Breast Cancer Progression and Drug Resistance via m6A Modification of Constituents of the CDKN1A/EMT and BAX/caspase-9/-3/-8 Signalling Pathways | Ouyang, D. et. al. | Research Square |
| 2021/11/28 | ALKBH5 Is Lowly Expressed in Esophageal Squamous Cell Carcinoma and Inhibits the Malignant Proliferation and Invasion of Tumor Cells. | Li J, Liu H, Dong S, Zhang Y, Li X, Wang J | Comput Math Methods Med |
| 2021/12/5 | Amelioration of acute myocardial infarction injury through targeted ferritin nanocages loaded with an ALKBH5 inhibitor. | Cheng P, Han H, Chen F, Cheng L, Ma C, Huang H, Chen C, Li H, Cai H, Huang H, Li G, Tao J | Acta Biomater |
| 2021/12/4 | LXA4 Enhances Prostate Cancer Progression Through Facilitating M2 Macrophage Polarization via Inhibition of METTL3 | Jia, G., et. al. | SSRN |
| 2021/12/6 | Identification and Validation of N6-methyladenosine-related Biomarkers for Bladder Cancer: Implications for Immunotherapy | Deng, H., et. al. | Research Square |
| 2021/12/13 | FTO promotes multiple myeloma progression by posttranscriptional activation of HSF1 in an m<sup>6</sup>A-YTHDF2-dependent manner. | Xu A, Zhang J, Zuo L, Yan H, Chen L, Zhao F, Fan F, Xu J, Zhang B, Zhang Y, Yin X, Cheng Q, Gao S, Deng J, Mei H, Huang Z, Sun C, Hu Y | Mol Ther |
| 2021/12/16 | N-acetyl-seryl-aspartyl-lysyl-proline (AcSDKP) mitigates the liver fibrosis via WTAP/m<sup>6</sup>A/Ptch1 axis through Hedgehog pathway. | Wei A, Zhao F, Hao A, Liu B, Liu Z | Gene |
| 2021/12/15 | Low Expression of YTH Domain-Containing 1 Promotes Microglial M1 Polarization by Reducing the Stability of Sirtuin 1 mRNA. | Zhou H, Xu Z, Liao X, Tang S, Li N, Hou S | Front Cell Neurosci |
| 2021/12/29 | S-adenosylmethionine-dependent methyltransferase inhibitor DZNep blocks transcription and translation of SARS-CoV-2 genome with a low tendency to select for drug-resistant viral variants. | Kumar R, Khandelwal N, Chander Y, Nagori H, Verma A, Barua A, Godara B, Pal Y, Gulati BR, Tripathi BN, Barua S, Kumar N | Antiviral Res |
| 2021/12/13 | N6-methyladenosine modification governs liver glycogenesis by stabilizing the glycogen synthase 2 mRNA | Zhang X., et. al. | Research Square |
| 2021/12/17 | METTL14-mediated Lnc-LSG1 m6A modification inhibits clear cell renal cell carcinoma metastasis via regulating ESRP2 ubiquitination | Shen D., et. al. | Nucleic Acids |
| 2022/1/3 | The m6A methyltransferase METTL3 affects autophagy and progression of nasopharyngeal carcinoma by regulating the stability of lncRNA ZFAS1. | Peng J, Zheng H, Liu F, Wu Q, Liu S | Infect Agent Cancer |
| 2022/1/1 | METTL3-mediated <i>N</i> <sup>6</sup>-methyladenosine modification governs pericyte dysfunction during diabetes-induced retinal vascular complication. | Suo L, Liu C, Zhang QY, Yao MD, Ma Y, Yao J, Jiang Q, Yan B | Theranostics |
| 2022/1/7 | N(6)-Methyladenosine RNA Methyltransferase Like 3 Inhibits Extracellular Matrix Synthesis of Endplate Chondrocytes by Downregulating Sex-Determining Region Y-Box Transcription Factor 9 Expression Under Tension. | Xiao L, Hu B, Ding B, Zhao Q, Liu C, ?–ner FC, Xu H | Osteoarthritis Cartilage |
| 2022/1/8 | MYC, mitochondrial metabolism and O-GlcNAcylation converge to modulate the activity and subcellular localization of DNA and RNA demethylases. | Lin AP, Qiu Z, Ethiraj P, Sasi B, Jaafar C, Rakheja D, Aguiar RCT | Leukemia |
| 2022/1/7 | METTL3 promotes lung adenocarcinoma tumor growth and inhibits ferroptosis by stabilizing SLC7A11 m<sup>6</sup>A modification. | Xu Y, Lv D, Yan C, Su H, Zhang X, Shi Y, Ying K | Cancer Cell Int |
| 2022/1/7 | Isovitexin protects against acute liver injury by targeting PTEN, PI3K and BiP via modification of m6A. | Huang Y, Chen S, Pang L, Feng Z, Su H, Zhu W, Wei J | Eur J Pharmacol |
| 2022/1/14 | ALKBH5-mediated N<sup>6</sup>-methyladenosine modification of TRERNA1 promotes DLBCL proliferation via p21 downregulation. | Song W, Fei F, Qiao F, Weng Z, Yang Y, Cao B, Yue J, Xu J, Zheng M, Li J | Cell Death Discov |
| 2021/12/15 | METTL3 facilitates the progression of hepatocellular carcinoma by modulating the m6A level of USP7. | Li Y, Cheng X, Chen Y, Zhou T, Li D, Zheng WV | Am J Transl Res |
| 2022/1/17 | New insights into the central sympathetic hyperactivity post-myocardial infarction: Roles of METTL3-mediated m<sup>6</sup> A methylation. | Qi L, Hu H, Wang Y, Hu H, Wang K, Li P, Yin J, Shi Y, Wang Y, Zhao Y, Lyu H, Feng M, Xue M, Li X, Li Y, Yan S | J Cell Mol Med |
| 2022/1/12 | ??-Elemene Restrains PTEN mRNA Degradation to Restrain the Growth of Lung Cancer Cells via METTL3-Mediated N6 Methyladenosine Modification | Feng Y. et. al. | Journal of Oncology |
| 2022/1/29 | piRNA-14633 promotes cervical cancer cell malignancy in a METTL14-dependent m6A RNA methylation manner. | Xie Q, Li Z, Luo X, Wang D, Zhou Y, Zhao J, Gao S, Yang Y, Fu W, Kong L, Sun T | J Transl Med |
| 2022/2/3 | Demethylase ALKBH5 suppresses invasion of gastric cancer via PKMYT1 m6A modification. | Hu Y, Gong C, Li Z, Liu J, Chen Y, Huang Y, Luo Q, Wang S, Hou Y, Yang S, Xiao Y | Mol Cancer |
| 2022/2/4 | N6-methyladenosine-dependent modification of circGARS acts as a new player that promotes SLE progression through the NF-??B/A20 axis. | Zhao X, Dong R, Zhang L, Guo J, Shi Y, Ge L, Wang J, Song Z, Ni B, You Y | Arthritis Res Ther |
| 2022/2/14 | METTL3 regulates LPS-induced inflammatory response via the NOD1 signaling pathway. | Cai Y, Yu R, Kong Y, Feng Z, Xu Q | Cell Signal |
| 2021/9/23 | The RNA N6-Methyladenosine Methyltransferase METTL3 Promotes the Progression of Kidney Cancer via N6-Methyladenosine-Dependent Translational Enhancement of ABCD1. | Shi Y, Dou Y, Zhang J, Qi J, Xin Z, Zhang M, Xiao Y, Ci W | Front Cell Dev Biol |
| 2022/2/15 | TBK1-METTL3 axis facilitates antiviral immunity. | Chen J, Wei X, Wang X, Liu T, Zhao Y, Chen L, Luo Y, Du H, Li Y, Liu T, Cao L, Zhou Z, Zhang Z, Liang L, Li L, Yan X, Zhang X, Deng X, Yang G, Yin P, Hao J, Yin Z, You F | Cell Rep |
| 2022/3/1 | m<sup>6</sup>A demethylase FTO regulates the apoptosis and inflammation of cardiomyocytes via YAP1 in ischemia-reperfusion injury. | Ke WL, Huang ZW, Peng CL, Ke YP | Bioengineered |
| 2022/2/14 | Global N6-Methyladenosine Profiling Revealed the Tissue-Specific Epitranscriptomic Regulation of Rice Responses to Salt Stress | Wang, Y. et .al. | Int. J. Mol. Sci. |
| 2022/2/12 | N<sup>6</sup>-methyladenosine RNA modification of glutamatergic neurons is associated with contextual fear discrimination. | Chang Y, Zhang J, Zhang J, Zhu W, Zheng Q, Qian Z, Wei C, Liu Y, Liu Z, Ren W, Han J | Physiol Behav |
| 2022/3/19 | ALKBH5 ameliorated liver fibrosis and suppressed HSCs activation via triggering PTCH1 activation in an m<sup>6</sup>A dependent manner. | Yang JJ, Wang J, Yang Y, Yang Y, Li J, Lu D, Lu C | Eur J Pharmacol |
| 2022/3/10 | PRMT5 regulates RNA m6A demethylation for doxorubicin sensitivity in breast cancer. | Wu Y, Wang Z, Han L, Guo Z, Yan B, Guo L, Zhao H, Wei M, Hou N, Ye J, Wang Z, Shi C, Liu S, Chen C, Chen S, Wang T, Yi J, Zhou J, Yao L, Zhou W, Ling R, Zhang J | Mol Ther |
| 2022/4/13 | Inhibition of METTL3 attenuates renal injury and inflammation by alleviating TAB3 m6A modifications via IGF2BP2-dependent mechanisms. | Wang JN, Wang F, Ke J, Li Z, Xu CH, Yang Q, Chen X, He XY, He Y, Suo XG, Li C, Yu JT, Jiang L, Ni WJ, Jin J, Liu MM, Shao W, Yang C, Gong Q, Chen HY, Li J, Wu YG, Meng XM | Sci Transl Med |
| 2022/3/6 | ALKBH5 Promotes Multiple Myeloma Tumorigenicity through inducing m<sup>6</sup>A-demethylation of SAV1 mRNA and Myeloma Stem Cell Phenotype. | Yu T, Yao L, Yin H, Teng Y, Hong M, Wu Q | Int J Biol Sci |
| 2022/4/1 | N6-methyladenosine methyltransferase WTAP-stabilized FOXD2-AS1 promotes the osteosarcoma progression through m<sup>6</sup>A/FOXM1 axis. | Ren Z, Hu Y, Sun J, Kang Y, Li G, Zhao H | Bioengineered |
| 2022/3/30 | METTL3 enhances NSD2 mRNA stability to reduce renal impairment and interstitial fibrosis in mice with diabetic nephropathy. | Tang W, Zhao Y, Zhang H, Peng Y, Rui Z | BMC Nephrol |
| 2022/3/30 | METTL14 promotes prostate tumorigenesis by inhibiting THBS1 via an m6A-YTHDF2-dependent mechanism. | Wang Y, Chen J, Gao WQ, Yang R | Cell Death Discov |
| 2022/4/1 | Role of N6-methyladenosine RNA modification in the imbalanced inflammatory homeostasis of arsenic-induced skin lesions. | Yang F, Zhang A | Environ Toxicol |
| 2022/4/4 | Analysis of the function and mechanism of DIRAS1 in osteosarcoma. | Liu H, Shu W, Liu T, Li Q, Gong M | Tissue Cell |
| 2022/4/26 | Drosophila Tet Is Required for Maintaining Glial Homeostasis in Developing and Adult Fly Brains | Frey F, Sandakly J, Ghannam M, Doueiry C, Hugosson F, Berlandi J, Ismail JN, Gayden T, Hasselblatt M, Jabado N, Shirinian M | eNeuro |
| 2022/4/11 | An Alternatively Spliced Variant of METTL3 Mediates Tumor Suppression in Hepatocellular Carcinoma. | Xu RY, Ding Z, Zhao Q, Ke TY, Chen S, Wang XY, Wang YY, Sheng MF, Wang W, Long N, Shen YX, Xu YZ, Shao W | Genes (Basel) |
| 2022/3/26 | N6-methyladenosine modified LINC00901 promotes pancreatic cancer progression through IGF2BP2/MYC axis | Peng, W. X. et. al. | Genes & Diseases |
| 2022/4/18 | Transcriptome-wide N6-methyladenosine methylome profiling of Bombyx mori reveals a potential mechanism of epigenetic regulation on diapause | Chen, Y.H. et. al. | Research Square |
| 2022/4/1 | MiR-192 attenuates high glucose-induced pyroptosis in retinal pigment epithelial cells via inflammasome modulation. | Gu C, Zhang H, Li Q, Zhao S, Gao Y | Bioengineered |
| 2022/5/26 | PDGF signaling inhibits mitophagy in glioblastoma stem cells through N6-methyladenosine. | Lv D, Gimple RC, Zhong C, Wu Q, Yang K, Prager BC, Godugu B, Qiu Z, Zhao L, Zhang G, Dixit D, Lee D, Shen JZ, Li X, Xie Q, Wang X, Agnihotri S, Rich JN | Dev Cell |
| 2022/6/1 | The genomic landscape of cholangiocarcinoma reveals the disruption of post-transcriptional modifiers. | Zhang Y, Ma Z, Li C, Wang C, Jiang W, Chang J, Han S, Lu Z, Shao Z, Wang Y, Wang H, Jiao C, Wang D, Wu X, Shen H, Wang X, Hu Z, Li X | Nat Commun |
| 2022/5/9 | Neutrophil extracellular traps mediate m6A modification and regulates sepsis-associated acute lung injury by activating ferroptosis in alveolar epithelial cells. | Zhang H, Liu J, Zhou Y, Qu M, Wang Y, Guo K, Shen R, Sun Z, Cata JP, Yang S, Chen W, Miao C | Int J Biol Sci |
| 2022/5/22 | The prognostic value of N6-methyladenosine RBM15 regulators in lung adenocarcinoma. | Ma M, Wang W, Wang B, Yang Y, Huang Y, Zhao G, Ye L | Cell Mol Biol (Noisy-le-grand) |
| 2022/5/25 | Long-term exercise training down-regulates m6A RNA demethylase FTO expression in the hippocampus and hypothalamus: An effective intervention for epigenetic modification | Liu, S.J, et. al. | Research Square |
| 2022/5/25 | Research progress on N6-methyladenosine in the human placenta. | Zhou W, Xue P, Yang Y, Xia L, Yu B | J Perinat Med |
| 2022/5/22 | The prognostic value of N6-methyladenosine RBM15 regulators in lung adenocarcinoma | Ma, M. et. al. | Cellular and Molecular Biology |
| 2022/5/7 | FTO mediated ERBB2 demethylation promotes tumor progression in esophageal squamous cell carcinoma cells. | Zhao F, Ge F, Xie M, Li Z, Zang C, Kong L, Pu Y, Zheng X, Tan Y | Clin Exp Metastasis |
| 2022/4/18 | METTL3-mediated m6A modification of STEAP2 mRNA inhibits papillary thyroid cancer progress by blocking the Hedgehog signaling pathway and epithelial-to-mesenchymal transition. | Zhu Y, Peng X, Zhou Q, Tan L, Zhang C, Lin S, Long M | Cell Death Dis |
| 2022/4/19 | ALKBH8B, a Putative RNA Demethylase, Plays a Role in the Response of Arabidopsis to Salt Stress and Abscisic Acid | Huong, T. T., et. al. | Journal of Plant Biology |
| 2022/7/1 | METTL3 mediates osteoblast apoptosis by regulating endoplasmic reticulum stress during LPS-induced inflammation. | Kong Y, Zhang Y, Cai Y, Li D, Yi B, Xu Q | Cell Signal |
| 2022/1/1 | DARS-AS1 recruits METTL3/METTL14 to bind and enhance DARS mRNA m<sup>6</sup>A modification and translation for cytoprotective autophagy in cervical cancer. | Shen W, Zhu M, Wang Q, Zhou X, Wang J, Wang T, Zhang J | RNA Biol |
| 2022/5/1 | Dynamic N6-methyladenosine modification of lncRNA modulated by METTL3 during bacterial disease development in an echinoderm. | Zhang S, Shao Y, Li D, Li C | Fish Shellfish Immunol |
| 2022/6/1 | p53 m6A modulation sensitizes hepatocellular carcinoma to apatinib through apoptosis. | Ke W, Zhang L, Zhao X, Lu Z | Apoptosis |
| 2022/7/18 | The m6A-induced lncRNA CASC8 promotes proliferation and chemoresistance via upregulation of hnRNPL in esophageal squamous cell carcinoma. | Wu Q, Zhang H, Yang D, Min Q, Wang Y, Zhang W, Zhan Q | Int J Biol Sci |
| 2022/8/11 | Comprehensive analysis of RNA m6A methylation in pressure overload-induced cardiac hypertrophy. | Li W, Xing C, Bao L, Han S, Luo T, Wang Z, Fan H | BMC Genomics |
| 2022/6/1 | LXA4 enhances prostate cancer progression by facilitating M2 macrophage polarization via inhibition of METTL3. | Jia G, Wang X, Wu W, Zhang Y, Chen S, Zhao J, Zhao W, Li W, Sun X, Han B | Int Immunopharmacol |
| 2022/9/5 | E6E7 regulates the HK2 expression in cervical cancer via GSK3??/FTO signal. | Liu C, Li Y, Dong C, Qu L, Zuo Y | Arch Biochem Biophys |
| 2022/6/1 | MiR-29a-3p Improves Acute Lung Injury by Reducing Alveolar Epithelial Cell PANoptosis. | Cui Y, Wang X, Lin F, Li W, Zhao Y, Zhu F, Yang H, Rao M, Li Y, Liang H, Dai M, Liu B, Chen L, Han D, Lu R, Peng W, Zhang Y, Song C, Luo Y, Pan P | Aging Dis |
| 2022/4/25 | Methyltransferase-Like 3 Rescues the Amyloid-beta protein-Induced Reduction of Activity-Regulated Cytoskeleton Associated Protein Expression <i>via</i> YTHDF1-Dependent N6-Methyladenosine Modification. | Xu C, Huang H, Zhang M, Zhang P, Li Z, Liu X, Fang M | Front Aging Neurosci |
| 2022/9/6 | Combination of high-fat diet and cadmium impairs testicular spermatogenesis in an m6A-YTHDF2-dependent manner. | Xiong YW, Tan LL, Zhang J, Zhu HL, Zheng XM, Chang W, Gao L, Wei T, Xu DX, Wang H | Environ Pollut |
| 2022/9/1 | Methyltransferase-like 3 leads to lung injury by up-regulation of interleukin 24 through N6-methyladenosine-dependent mRNA stability and translation efficiency in mice exposed to fine particulate matter 2.5. | He X, Zhang L, Liu S, Wang J, Liu Y, Xiong A, Jiang M, Luo L, Ying X, Li G | Environ Pollut |
| 2022/3/28 | Maslinic acid protects against pressure-overload-induced cardiac hypertrophy by blocking METTL3-mediated m<sup>6</sup>A methylation. | Fang M, Deng J, Zhou Q, Hu Z, Yang L | Aging (Albany NY) |
| 2022/10/1 | FTO-dependent N6-Methyladenosine regulates the progression of endometriosis via the ATG5/PKM2 Axis. | Wang H, Liang Z, Gou Y, Li Z, Cao Y, Jiao N, Tan J, Yu Y, Zhang Z | Cell Signal |
| 2022/10/15 | Role of RNA m6A modification in titanium dioxide nanoparticle-induced acute pulmonary injury: An in vitro and in vivo study | Ruan F, Liu C, Wang Y, Cao X, Tang Z, Xu J, Zeng J, Yin H, Zheng N, Yang C, Zuo Z, He C | Environ Pollut |
| 2022/3/21 | The Effects of Moxibustion on Learning and Memory and m6A RNA Methylation in APP/PS1 Mice. | Huang Q, Li CY, Zhang N, Zhang Q, Li HY, Shen Y, Xie LS, Yu SG, Wu QF | Evid Based Complement Alternat Med |
| 2022/7/11 | Altered m6A RNA methylation contributes to hippocampal memory deficits in Huntington's disease mice. | Pupak A, Singh A, Sancho-Balsells A, Alcal??-Vida R, Espina M, Giralt A, Mart?? E, ??rom UAV, Gin??s S, Brito V | Cell Mol Life Sci |
| 2022/6/29 | Limited effects of m6A modification on mRNA partitioning into stress granules. | Khong A, Matheny T, Huynh TN, Babl V, Parker R | Nat Commun |
| 2022/5/14 | m6A demethylase FTO promotes tumor progression via regulation of lipid metabolism in esophageal cancer. | Duan X, Yang L, Wang L, Liu Q, Zhang K, Liu S, Liu C, Gao Q, Li L, Qin G, Zhang Y | Cell Biosci |
| 2022/4/6 | METTL3-mediated m6A modification of TIMP2 mRNA promotes podocyte injury in diabetic nephropathy. | Jiang L, Liu X, Hu X, Gao L, Zeng H, Wang X, Huang Y, Zhu W, Wang J, Wen J, Meng X, Wu Y | Mol Ther |
| 2022/3/8 | SPI1-induced? downregulation of FTO promotes GBM progression by regulating pri-miR-10a processing in an m6A-dependent manner. | Zhang S, Zhao S, Qi Y, Li B, Wang H, Pan Z, Xue H, Jin C, Qiu W, Chen Z, Guo Q, Fan Y, Xu J, Gao Z, Wang S, Guo X, Deng L, Ni S, Xue F, Wang J, Zhao R, Li G | Mol Ther Nucleic Acids |
| 2022/5/25 | Maternal Oxidized Soybean Oil Administration in Rats during Pregnancy and Lactation Alters the Intestinal DNA Methylation in Offspring. | Wang C, Sun H, Jiang X, Guan X, Gao F, Shi B | J Agric Food Chem |
| 2022/9/2 | Functional Characterization of Two RNA Methyltransferase Genes METTL3 and METTL14 Uncovers the Roles of m6A in Mediating Adaptation of Plutella xylostella to Host Plants. | Wang BB, Lai YF, Li FF, Jiao L, Qiao QX, Li SY, Xiang XJ, Liao H, You MS, He WY | Int J Mol Sci |
| 2022/9/26 | m6A transferase METTL3 regulates endothelial-mesenchymal transition in diabetic retinopathy via lncRNA SNHG7/KHSRP/MKL1 axis. | Cao X, Song Y, Huang LL, Tian YJ, Wang XL, Hua LY | Genomics |
| 2022/7/28 | m6A methyltransferase METTL3-induced lncRNA SNHG17 promotes lung adenocarcinoma gefitinib resistance by epigenetically repressing LATS2 expression. | Zhang H, Wang SQ, Wang L, Lin H, Zhu JB, Chen R, Li LF, Cheng YD, Duan CJ, Zhang CF | Cell Death Dis |
| 2022/10/15 | Dual effects of zearalenone on aflatoxin B1-induced liver and mammary gland toxicity in pregnant and lactating rats. | Wu K, Jia S, Xue D, Rajput SA, Liu M, Qi D, Wang S | Ecotoxicol Environ Saf |
| 2022/7/14 | METTL3 mediates Ang-II-induced cardiac hypertrophy through accelerating pri-miR-221/222 maturation in an m6A-dependent manner. | Zhang R, Qu Y, Ji Z, Hao C, Su Y, Yao Y, Zuo W, Chen X, Yang M, Ma G | Cell Mol Biol Lett |
| 2022/8/1 | N6-methyladenosine demethylase ALKBH5 suppresses colorectal cancer progression potentially by decreasing PHF20 mRNA methylation. | Zhang Z, Wang L, Zhao L, Wang Q, Yang C, Zhang M, Wang B, Jiang K, Ye Y, Wang S, Shen Z | Clin Transl Med |
| 2022/9/4 | Gene signatures, immune infiltration, and drug sensitivity based on a comprehensive analysis of m6a RNA methylation regulators in cervical cancer. | Lu X, Li R, Ying Y, Zhang W, Wang W | J Transl Med |
| 2022/10/5 | N6-methyladenosine-related single-nucleotide polymorphism analyses identify oncogene RNFT2 in bladder cancer. | Lv J, Song Q, Bai K, Han J, Yu H, Li K, Zhuang J, Yang X, Yang H, Lu Q | Cancer Cell Int |
| 2022/9/11 | N6-methyladenosine of Socs1 modulates macrophage inflammatory response in different stiffness environments. | Hu Z, Li Y, Yuan W, Jin L, Leung WK, Zhang C, Yang Y | Int J Biol Sci |
| 2022/10/10 | RNA-m6A modification of HDGF mediated by Mettl3 aggravates the progression of atherosclerosis by regulating macrophages polarization via energy metabolism reprogramming. | Zheng L, Chen X, Yin Q, Gu J, Chen J, Chen M, Zhang Y, Dong M, Jiang H, Yin N, Chen H, Li X | Biochem Biophys Res Commun |
| 2022/10/18 | Identification of miR-30c-5p as a tumor suppressor by targeting the m<sup>6</sup> A reader HNRNPA2B1 in ovarian cancer. | Wu Q, Li G, Gong L, Cai J, Chen L, Xu X, Liu X, Zhao J, Zeng Y, Gao R, Yu L, Wang Z | Cancer Med |
| 2022/10/25 | LncRNA FENDRR with m6A RNA methylation regulates hypoxia-induced pulmonary artery endothelial cell pyroptosis by mediating DRP1 DNA methylation. | Wang X, Li Q, He S, Bai J, Ma C, Zhang L, Guan X, Yuan H, Li Y, Zhu X, Mei J, Gao F, Zhu D | Mol Med |
| 2022/10/24 | Comprehensive Analysis of Blood-Based m6A Methylation in Human Ischemic Stroke. | Zhu L, Liu S, Liao F, Yang J, Liang T, Yang Y, Huang X, Gu L, Su L | Mol Neurobiol |
| 2022/11/1 | RNA m6A reader IGF2BP3 promotes metastasis of triple-negative breast cancer via SLIT2 repression. | Jiang T, He X, Zhao Z, Zhang X, Wang T, Jia L | FASEB J |
| 2022/10/27 | Acetaminophen changes the RNA m6A levels and m6A-related proteins expression in IL-1??-treated chondrocyte cells. | Gao J, Li Y, Liu Z, Wang D, Zhang H | BMC Mol Cell Biol |
| 2022/10/27 | Senescent neutrophils-derived exosomal piRNA-17560 promotes chemoresistance and EMT of breast cancer via FTO-mediated m6A demethylation. | Ou B, Liu Y, Gao Z, Xu J, Yan Y, Li Y, Zhang J | Cell Death Dis |
| 2022/11/1 | Downregulation of METTL14 improves postmenopausal osteoporosis via IGF2BP1 dependent posttranscriptional silencing of SMAD1. | Huang C, Wang Y | Cell Death Dis |
| 2022/11/1 | N6-methyladenosine reader YTHDF3 regulates melanoma metastasis via its 'executor'LOXL3. | Shi HZ, Xiong JS, Gan L, Zhang Y, Zhang CC, Kong YQ, Miao QJ, Tian CC, Li R, Liu JQ, Zhang EJ, Bu WB, Wang Y, Cheng XF, Sun JF, Chen H | Clin Transl Med |
| 2022/11/3 | N-methyladenosine (m6A) writer KIAA1429 accelerates gastric cancer oxaliplatin chemoresistance by targeting FOXM1. | Tang B, Li M, Xu Y, Li X | J Cancer Res Clin Oncol |
| 2022/10/28 | Polychlorinated biphenyls alter hepatic m6A mRNA methylation in a mouse model of environmental liver disease. | Petri BJ, Piell KM, Wahlang B, Head KZ, Andreeva K, Rouchka EC, Cave MC, Klinge CM | Environ Res |
| 2022/12/22 | FTO promotes innate immunity by controlling NOD1 expression via m(6)A-YTHDF2 manner in teleost. | Geng S, Zheng W, Zhao Y, Xu T | iScience |
| 2022/12/1 | WTAP dysregulation-mediated HMGN3-m6A modification inhibited trophoblast invasion in early-onset preeclampsia. | Bian Y, Li J, Shen H, Li Y, Hou Y, Huang L, Song G, Qiao C | FASEB J |
| 2022/11/24 | KIAA1429 mediates epithelial mesenchymal transition in sorafenib-resistant hepatocellular carcinoma through m6A methylation modification. | Kuang Y, Cheng Y, Wang J, Li H, Cao X, Wang Y | Cancer Med |
| 2022/12/3 | m6A 'writer' KIAA1429 regulates the proliferation? and? migration of endothelial cells in atherosclerosis. | Rong J, Jie Y, Zhao H | Mol Biotechnol |
| 2022/12/22 | METTL3 is aberrantly expressed in endometriosis and suppresses proliferation, invasion, and migration of endometrial stromal cells. | Zhang QC | Kaohsiung J Med Sci |
| 2022/11/2 | Integrative Transcriptomic Analysis Identify Potential m6A Pathway-Related Drugs That Inhibit Cancer Cell Proliferation. | Yi J, Liu R, Liu Y, Guo T, Li Y, Zhou Y | Genes (Basel) |
| 2023/1/14 | Cross-Talk between N6-Methyladenosine and Their Related RNAs Defined a Signature and Confirmed m6A Regulators for Diagnosis of Endometriosis. | Wang X, Zhao X, Wang J, Wu H, Cheng Y, Guo Q, Liang T, Zhang G | Int J Mol Sci |
| 2022/12/1 | M2-TAMs promote immunoresistance in lung adenocarcinoma by enhancing METTL3-mediated m6A methylation. | Wu L, Cheng D, Yang X, Zhao W, Fang C, Chen R, Ji M | Ann Transl Med |
| 2023/1/3 | METTL3 alleviates D-gal-induced renal tubular epithelial cellular senescence via promoting miR-181a maturation. | Zhang Y, Ni X, Wei L, Yu Y, Zhu B, Bai Y, Pei X, Gao F, Guo L, Yong Z, Zhao W | Mech Ageing Dev |
| 2023/1/7 | Bone Marrow Mesenchymal Stem Cells Reversed Ovarian Aging-related m6A RNA Methylation Modification Profile in Aged Granulosa Cells. | Tian C, An Y, Zhao J, Zhu X, Wei W, Ruan G, Li Y, Pan X | Stem Cell Rev Rep |
| 2023/1/11 | METTL3 Regulates Osteoclast Biological Behaviors via iNOS/NO-Mediated Mitochondrial Dysfunction in Inflammatory Conditions. | Li D, He J, Fang C, Zhang Y, He M, Zhang Z, Hou J, Xu Q | Int J Mol Sci |
| 2023/1/17 | WTAP-mediated m(6)A modification modulates bone marrow mesenchymal stem cells differentiation potential and osteoporosis. | You Y, Liu J, Zhang L, Li X, Sun Z, Dai Z, Ma J, Jiao G, Chen Y | Cell Death Dis |
| 2023/1/23 | METTL3 knockdown promotes temozolomide sensitivity of glioma stem cells via decreasing MGMT and APNG mRNA stability. | Shi J, Zhang P, Dong X, Yuan J, Li Y, Li S, Cheng S, Ping Y, Dai X, Dong J | Cell Death Discov |
| 2023/1/30 | FTO-dependent m(6)A modification of Plpp3 in circSCMH1-regulated vascular repair and functional recovery following stroke. | Li B, Xi W, Bai Y, Liu X, Zhang Y, Li L, Bian L, Liu C, Tang Y, Shen L, Yang L, Gu X, Xie J, Zhou Z, Wang Y, Yu X, Wang J, Chao J, Han B, Yao H | Nat Commun |
| 2023/1/30 | New insights on the interaction between m(6)A modification and non-coding RNA in cervical squamous cell carcinoma. | Shen G, Li F, Wang Y, Huang Y, Aizezi G, Yuan J, Ma C, Lin C | World J Surg Oncol |
| 2023/2/6 | Methyltransferase-like 3 aggravates endoplasmic reticulum stress in preeclampsia by targeting TMBIM6 in YTHDF2-dependent manner. | Chen Y, Liu X, Li L, He X, Zheng F, Zhang Y, Gao H, Jin Z, Wu D, Wang Q, Tao H, Zhao Y, Liu W, Zou L | Mol Med |
| 2023/2/10 | METTL3 depletion contributes to tumour progression and drug resistance via N6 methyladenosine-dependent mechanism in HR+HER2-breast cancer. | Ouyang D, Hong T, Fu M, Li Y, Zeng L, Chen Q, He H, Wen Y, Cheng Y, Zhou M, Zou Q, Yi W | Breast Cancer Res |
| 2023/2/20 | m(6)A methylation-induced NR1D1 ablation disrupts the HSC circadian clock and promotes hepatic fibrosis. | Chen L, Xia S, Wang F, Zhou Y, Wang S, Yang T, Li Y, Xu M, Zhou Y, Kong D, Zhang Z, Shao J, Xu X, Zhang F, Zheng S | Pharmacol Res |
| 2023/2/15 | The m(6)A methyltransferase METTL3 affects cell proliferation and migration by regulating YAP expression in Hirschsprung disease. | Huang Z, Luo C, Hou X, Yu D, Su Y, Li X, Luo Y, Liao G, Mu J, Wu K | Pediatr Surg Int |
| 2023/3/1 | METTL3 promotes SMSCs chondrogenic differentiation by targeting the MMP3, MMP13, and GATA3. | Hu B, Zou X, Yu Y, Jiang Y, Xu H | Regen Ther |
| 2023/12/1 | WTAP regulates autophagy in colon cancer cells by inhibiting FLNA through N6-methyladenosine. | Huang L, Shao J, Xu X, Hong W, Yu W, Zheng S, Ge X | Cell Adh Migr |
| 2023/2/23 | METTL3-mediated m6A methylation regulates granulosa cells autophagy during follicular atresia in pig ovaries. | Li Z, Ruan Z, Feng Y, Wang Y, Zhang J, Lu C, Shi D, Lu F | Theriogenology |
| 2023/3/2 | N(6)-methyladenosine of Spi2a attenuates inflammation and sepsis-associated myocardial dysfunction in mice. | Wang X, Ding Y, Li R, Zhang R, Ge X, Gao R, Wang M, Huang Y, Zhang F, Zhao B, Liao W, Du J | Nat Commun |
| 2023/3/21 | METTL3-mediated m6A modification of HMGA2 mRNA promotes subretinal fibrosis and epithelial-mesenchymal transition. | Wang Y, Chen Y, Liang J, Jiang M, Zhang T, Wan X, Wu J, Li X, Chen J, Sun J, Hu Y, Huang P, Feng J, Liu T, Sun X | J Mol Cell Biol |
| 2023/3/22 | Epitranscriptomic profiling of m6A RNA methylation in renal epithelial tubular cells stimulated with calcium oxalate crystals through microarray analysis. | Yang BY, Zhao FZ, Li J, Wang XC, Zhao HM, Tian Y | Urolithiasis |
| 2023/3/22 | METTL3-METTL14 complex induces necroptosis and inflammation of vascular smooth muscle cells via promoting N6 methyladenosine mRNA methylation of receptor-interacting protein 3 in abdominal aortic aneurysms. | Li K, Zhang D, Zhai S, Wu H, Liu H | J Cell Commun Signal |
| 2023/3/27 | m(6)A reader IGF2BP1 accelerates apoptosis of high glucose-induced vascular endothelial cells in a m(6)A-HMGB1 dependent manner. | Liang A, Liu J, Wei Y, Liao Y, Wu F, Ruan J, Li J | PeerJ |
| 2023/3/28 | METTL3 enhances pancreatic ductal adenocarcinoma progression and gemcitabine resistance through modifying DDX23 mRNA N6 adenosine methylation. | Lin C, Li T, Wang Y, Lai S, Huang Y, Guo Z, Zhang X, Weng S | Cell Death Dis |
| 2023/3/31 | Chinese Ecliptae herba (Eclipta prostrata (L.) L.) extract and its component wedelolactone enhances osteoblastogenesis of bone marrow mesenchymal stem cells via targeting METTL3-mediated m6A RNA methylation. | Tian S, Li YL, Wang J, Dong RC, Wei J, Ma Y, Liu YQ | J Ethnopharmacol |
| 2023/4/3 | m6A methyltransferase METTL3 programs CD4+ T-cell activation and effector T-cell differentiation in systemic lupus erythematosus. | Lu S, Wei X, Zhu H, Hu Z, Zheng M, Wu J, Zhao C, Yang S, Feng D, Jia S, Zhao H, Zhao M | Mol Med |
| 2023/4/3 | WTAP-Mediated m6A RNA Methylation Regulates the Differentiation of Bone Marrow Mesenchymal Stem Cells via the miR-29b-3p/HDAC4 Axis. | Liu J, You Y, Sun Z, Zhang L, Li X, Dai Z, Ma J, Chen Y, Jiao G | Stem Cells Transl Med |
| 2023/3/24 | Targeted Demethylation of the TGF??1 mRNA Promotes Myoblast Proliferation via Activating the SMAD2 Signaling Pathway. | Deng K, Liu Z, Li X, Zhang Z, Fan Y, Huang Q, Zhang Y, Wang F | Cells |
| 2023/4/7 | Comprehensive analyses of molecular features, prognostic values, and regulatory functionalities of m(6)A-modified long non-coding RNAs in lung adenocarcinoma. | Ping Y, Huang J, Zhu J, Sun Z, Shang A, Chen C, Liu W, Li D | Clin Epigenetics |
| 2022/12/16 | Stage-specific requirement for METTL3-dependent m(6)A modification during dental pulp stem cell differentiation. | Luo H, Liu W, Zhou Y, Zhang Y, Wu J, Wang R, Shao L | J Transl Med |
| 2023/4/14 | YTHDF1 phase separation triggers the fate transition of spermatogonial stem cells by activating the I??B-NF-??B-CCND1 axis. | Fang Q, Tian GG, Wang Q, Liu M, He L, Li S, Wu J | Cell Rep |
| 2023/3/31 | YTHDC2-mediated m6A mRNA modification of Id3 suppresses cisplatin resistance in non-small cell lung cancer. | Wang X, Hu Y, Li X, Zhu C, Chen F | J Thorac Dis |
| 2023/4/11 | Integrated analysis of transcriptome-wide m(6)A methylation in a Cd-induced kidney injury rat model. | Li S, Zhou H, Liang Y, Yang Q, Zhang J, Shen W, Lei L | Ecotoxicol Environ Saf |
| 2023/4/13 | Critical role of transcriptome-wide m6A methylation in the aqueous humor of patients with pseudoexfoliation glaucoma. | Guan J, Li Z, Wumaier A, Ma Y, Xie L, Wu H, Chen R, Zhu Y, Zhuo Y | Exp Eye Res |
| 2023/4/16 | The deficiency of N6-methyladenosine demethylase ALKBH5 enhances the neurodegenerative damage induced by cobalt. | Zheng C, Yu G, Su Q, Wu L, Tang J, Lin X, Chen Y, Guo Z, Zheng F, Zheng H, Lin L, Tang Y, Wu S, Li H | Sci Total Environ |
| 2023/4/19 | KIAA1429-mediated m6A modification of CHST11 promotes progression of diffuse large B-cell lymphoma by regulating Hippo-YAP pathway. | Chen X, Lu T, Cai Y, Han Y, Ding M, Chu Y, Zhou X, Wang X | Cell Mol Biol Lett |
| 2023/4/19 | METTL16, an evolutionarily conserved m6A methyltransferase member, inhibits the antiviral immune response of miiuy croaker (Miichthys miiuy). | Zhao Y, Luo Q, Wang W, Geng S, Sun Y, Xu T | Dev Comp Immunol |
| 2023/4/1 | N (6)-methyladenosine modification contributes to respiratory syncytial virus infection. | Li Z, Liu Y, Zhang L, Tian J, Wang H, Ding H, Nie J, Pi H, Wang B, Liu D | Heliyon |
| 2023/4/14 | Alteration of m(6)A-Tagged RNA Profiles in Bone Originated from Periprosthetic Joint Infection. | Cai Y, Chen X, Huang C, Chen Y, Zhang C, Huang Z, Zhang W, Tang Y, Fang X | J Clin Med |
| 2023/5/3 | Carbon Dots from Lycium barbarum Attenuate Radiation-Induced Bone Injury by Inhibiting Senescence via METTL3/Clip3 in an m(6)A-Dependent Manner. | Guo Z, Wang Z, Liu Y, Wu H, Zhang Q, Han J, Liu J, Zhang C | ACS Appl Mater Interfaces |
| 2023/4/28 | ZBTB7C m6A modification incurred by METTL3 aberration promotes osteosarcoma progression. | An X, Wu W, Yang L, Dong J, Liu B, Guo J, Chen J, Guo B, Cao W, Jiang Q | Transl Res |
| 2023/4/29 | LncRNA GAS5 regulated by FTO-mediated m6A demethylation promotes autophagic cell death in NSCLC by targeting UPF1/BRD4 axis. | Fu Y, Liu L, Wu H, Zheng Y, Zhan H, Li L | Mol Cell Biochem |
| 2023/5/1 | Disruption of the mouse liver epitranscriptome by long-term aroclor 1260 exposure. | Piell KM, Petri BJ, Head KZ, Wahlang B, Xu R, Zhang X, Pan J, Rai SN, de Silva K, Chariker JH, Rouchka EC, Tan M, Li Y, Cave MC, Klinge CM | Environ Toxicol Pharmacol |
| 2023/4/28 | A germline variant in the BET1L 3'-UTR confers colorectal cancer susceptibility by reducing miRNA binding and m6A modification. | Li S, Du M, Xu K, Ben S, Zhu T, Guo M, Xin J, Zhu L, Gu D, Zhang Z, Wang M | Cancer Res |
| 2023/5/6 | m(6)A-dependent mevalonate kinase in juvenile hormone synthesis pathway regulates the diapause process of bivoltine silkworm (Bombyx mori). | Chen YH, Jiang T, Yasen A, Fan BY, Zhu J, Wang MX, Qian P, Shen XJ | Mol Biol Rep |
| 2023/5/8 | RNA N6-methyladenosine reader IGF2BP3 interacts with MYCN and facilitates neuroblastoma cell proliferation. | Zhu K, Gao T, Wang Z, Zhang L, Tan K, Lv Z | Cell Death Discov |
| 2021/7/1 | The Emerging Roles of RNA m(6)A Methylation and Demethylation as Critical Regulators of Tumorigenesis, Drug Sensitivity, and Resistance. | Lan Q, Liu PY, Bell JL, Wang JY, H??ttelmaier S, Zhang XD, Zhang L, Liu T | Cancer Res |
| 2023/4/15 | METTL3 regulates alternative splicing of cell cycle-related genes via crosstalk between mRNA m(6)A modifications and splicing factors. | Kim Y, Shin S, Kwon S, Moon K, Baek SV, Jo A, Kim HS, Hwang GH, Bae S, Kim YH, Cho SY, Oh JM | Am J Cancer Res |
| 2023/5/9 | N(6) -methyladenosine mRNA modification regulates transcripts stability associated with cotton fiber elongation. | Xing K, Liu Z, Liu L, Zhang J, Qanmber G, Wang Y, Liu L, Gu Y, Zhang C, Li S, Zhang Y, Yang Z | Plant J |
| 2023/5/11 | m(6)A eraser ALKBH5 mitigates the apoptosis of cardiomyocytes in ischemia reperfusion injury through m(6)A/SIRT1 axis. | Liu L, Liu Z | PeerJ |
| 2023/5/13 | Short-chain fatty acid-butyric acid ameliorates granulosa cells inflammation through regulating METTL3-mediated N6-methyladenosine modification of FOSL2 in polycystic ovarian syndrome. | Liu K, He X, Huang J, Yu S, Cui M, Gao M, Liu L, Qian Y, Xie Y, Hui M, Hong Y, Nie X | Clin Epigenetics |
| 2023/5/15 | Epigenetic-Based Regulation of Transcriptome in Escherichia coli Adaptive Antibiotic Resistance. | D'Aquila P, De Rango F, Paparazzo E, Passarino G, Bellizzi D | Microbiol Spectr |
| 2023/5/15 | m6A Modification Mediates Exosomal LINC00657 to Trigger Breast Cancer Progression Via Inducing Macrophage M2 Polarization. | Chen J, Zhou Y, Wu M, Yuan Y, Wu W | Clin Breast Cancer |
| 2023/5/16 | HPV E6 promotes cell proliferation of cervical cancer cell by accelerating accumulation of RBM15 dependently of autophagy inhibition. | Nie G, Tang B, Lv M, Li D, Li T, Ou R, Xu Y, Wen J | Cell Biol Int |
| 2023/5/17 | METTL14 represses osteoclast formation to ameliorate osteoporosis via enhancing GPX4 mRNA stability. | Deng M, Luo J, Cao H, Li Y, Chen L, Liu G | Environ Toxicol |
| 2023/5/19 | METTL3 promotes pancreatic cancer proliferation and stemness by increasing stability of ID2 mRNA in a m6A-dependent manner. | Chen J, Zhang H, Xiu C, Gao C, Wu S, Bai J, Shen Q, Yin T | Cancer Lett |
| 2023/5/23 | RBM33 is a unique m(6)A RNA-binding protein that regulates ALKBH5 demethylase activity and substrate selectivity. | Yu F, Zhu AC, Liu S, Gao B, Wang Y, Khudaverdyan N, Yu C, Wu Q, Jiang Y, Song J, Jin L, He C, Qian Z | Mol Cell |
| 2023/5/30 | Effect of prenatal perfluoroheptanoic acid exposure on spermatogenesis in offspring mice. | Zhou Y, Sun W, Tang Q, Lu Y, Li M, Wang J, Han X, Wu D, Wu W | Ecotoxicol Environ Saf |
| 2023/6/1 | The role of m6A methylation in prenatal maternal psychological distress and birth outcome. | Li J, Gao X, Wang S, Yao D, Shao S, Wu H, Xu M, Yi Q, Xie L, Zhu Z, Song D, Li H | J Affect Disord |
| 2023/6/5 | Tumor-associated macrophages promote cisplatin resistance in ovarian cancer cells by enhancing WTAP-mediated N6-methyladenosine RNA methylation via the CXCL16/CXCR6 axis. | Hong L, Wang X, Zheng L, Wang S, Zhu G | Cancer Chemother Pharmacol |
| 2023/6/13 | Role of miR-300-3p in Leydig cell function and differentiation: A therapeutic target for obesity-related testosterone deficiency. | Liang J, Chen D, Xiao Z, Wei S, Liu Y, Wang C, Wang Z, Feng Y, Lei Y, Hu M, Deng J, Wang Y, Zhang Q, Yang Y, Huang Y | Mol Ther Nucleic Acids |
| 2023/6/12 | Mechanistic exploration on neurodevelopmental toxicity induced by upregulation of alkbh5 targeted by triclosan exposure to larval zebrafish. | Wang W, Li X, Qian Q, Yan J, Huang H, Wang X, Wang H | J Hazard Mater |
| 2023/6/13 | Oxidative Stress Induced by Arsenite is Involved in YTHDF2 Phase Separation. | Man J, Zhang Q, Zhao T, Sun D, Sun W, Long K, Zhang Z | Biol Trace Elem Res |
| 2023/6/13 | METTL14 is decreased and regulates m(6) A modification of ?±-synuclein in Parkinson's disease. | He H, Zhang Q, Liao J, Lei J, Luo M, Huang J, Chen M, Shen Y, Wang J, Xu P, Xiao Y | J Neurochem |
| 2023/6/13 | Therapeutic m(6)A Eraser ALKBH5 mRNA-Loaded Exosome-Liposome Hybrid Nanoparticles Inhibit Progression of Colorectal Cancer in Preclinical Tumor Models. | Wu S, Yun J, Tang W, Familiari G, Relucenti M, Wu J, Li X, Chen H, Chen R | ACS Nano |
| 2023/6/14 | FTO alleviates cerebral ischemia/reperfusion-induced neuroinflammation by decreasing cGAS mRNA stability in an m6A-dependent manner. | Yu Z, Zheng L, Geng Y, Zhang Y, Wang Y, You G, Cai M, Li M, Cheng X, Zan J | Cell Signal |
| 2023/6/12 | FTO promotes the progression of cervical cancer by regulating the N6-methyladenosine modification of ZEB1 and Myc. | Wang A, Jin C, Wang Y, Yu J, Wang R, Tian X | Mol Carcinog |
| 2023/6/1 | M6A modification promotes blood-brain barrier breakdown during cerebral ischemia/reperfusion injury through increasing matrix metalloproteinase 3 expression. | Liang E, Xiao S, Zhao C, Zhang Y, Fu G | Heliyon |
| 2023/6/23 | A cancer-associated METTL14 mutation induces aberrant m6A modification, affecting tumor growth. | Miyake K, Costa Cruz PH, Nagatomo I, Kato Y, Motooka D, Satoh S, Adachi Y, Takeda Y, Kawahara Y, Kumanogoh A | Cell Rep |
| 2023/6/23 | METTL3-mediated m6A modification of SIRT1 mRNA inhibits progression of endometriosis by cellular senescence enhancing. | Wang X, Wang J, Zhao X, Wu H, Li J, Cheng Y, Guo Q, Cao X, Liang T, Sun L, Zhang G | J Transl Med |
| 2023/6/23 | METTL3-mediated m6A methylation orchestrates mRNA stability and dsRNA contents to equilibrate ???? T1 and ???? T17 cells. | Xiao Z, Wang S, Tian Y, Lv W, Sheng H, Zhan M, Huang Q, Zhang Z, Zhu L, Zhu C, Zhong H, Wen Q, Liu Z, Tan J, Xu Y, Yang M, Liu Y, Flavell RA, Yang Q, Cao G, Yin Z | Cell Rep |
| 2023/6/28 | Expression profiling of N6-methyladenosine-modified mRNA in PC12 cells in response to unconjugated bilirubin. | Zhou J, Liao S, Zhang C, Luo J, Li G, Li H | Mol Biol Rep |
| 2023/7/1 | Enhancement of TKI sensitivity in lung adenocarcinoma through m6A-dependent translational repression of Wnt signaling by circ-FBXW7. | Li K, Peng ZY, Wang R, Li X, Du N, Liu DP, Zhang J, Zhang YF, Ma L, Sun Y, Tang SC, Ren H, Yang YP, Sun X | Mol Cancer |
| 2023/6/1 | METTL3 Affects Spinal Cord Neuronal Apoptosis by Regulating Bcl-2 m6A Modifications After Spinal Cord Injury. | Guo S, Lin T, Chen G, Shangguan Z, Zhou L, Chen Z, Shi T, Chen D, Wang Z, Liu W | Neurospine |
| 2023/7/5 | FTO-dependent m(6)A regulates muscle fiber remodeling in an NFATC1-YTHDF2 dependent manner. | Wang W, Du X, Luo M, Yang N | Clin Epigenetics |
| 2023/7/1 | m(6)A??‘mediated LINC02038 inhibits colorectal cancer progression via regulation of the FAM172A/PI3K/AKT pathway via competitive binding with miR??‘552??‘5p. | Liu W, Zhang Z, Luo X, Qian K, Huang B, Liang J, Ma Z, Deng J, Yang C | Int J Oncol |
| 2023/7/10 | Dysregulated m6A methylation modification is associated with human peri-implantitis - A pilot study. | Krishnamoorthy HS, Kannan B, Ganapathy D, Jayaseelan VP, Arumugam P | J Stomatol Oral Maxillofac Surg |
| 2023/7/10 | Inhibition of CDK1 Overcomes Oxaliplatin Resistance by Regulating ACSL4-mediated Ferroptosis in Colorectal Cancer. | Zeng K, Li W, Wang Y, Zhang Z, Zhang L, Zhang W, Xing Y, Zhou C | Adv Sci (Weinh) |
| 2023/7/5 | Dynamic N6-methyladenosine RNA methylation landscapes reveal epi-transcriptomic modulation induced by ammonia nitrogen exposure in the Pacific whiteleg shrimp Litopenaeus vannamei. | Lei Y, Yuan Z, Zeng Q, Wan B, Liu J, Wang W | J Hazard Mater |
| 2023/6/1 | Effects and translatomics characteristics of a small-molecule inhibitor of METTL3 against non-small cell lung cancer. | Xiao H, Zhao R, Meng W, Liao Y | J Pharm Anal |
| 2023/7/15 | Analysis of N(6)-methyladenosine reveals a new important mechanism regulating the salt tolerance of sugar beet (Beta vulgaris). | Li J, Wang J, Pang Q, Yan X | Plant Sci |
| 2023/7/17 | The rs1421085 variant within FTO promotes brown fat thermogenesis. | Zhang Z, Chen N, Yin N, Liu R, He Y, Li D, Tong M, Gao A, Lu P, Zhao Y, Li H, Zhang J, Zhang D, Gu W, Hong J, Wang W, Qi L, Ning G, Wang J | Nat Metab |
| 2023/7/16 | METTL3-dependent m6A modification mediates bladder remodeling after partial bladder outlet obstruction through CCN2 activation. | Yang Y, Long J, Yang J, Zheng H, Lai Y, Chen C, Tang F, Gao Y, Chen L, He Z | Neurourol Urodyn |
| 2023/7/19 | Poly(GR) interacts with key stress granule factors promoting its assembly into cytoplasmic inclusions. | Park J, Wu Y, Shao W, Gendron TF, van der Spek SJF, Sultanakhmetov G, Basu A, Castellanos Otero P, Jones CJ, Jansen-West K, Daughrity LM, Phanse S, Del Rosso G, Tong J, Castanedes-Casey M, Jiang L, Libera J, Oskarsson B, Dickson DW, Sanders DW, Brangwynne CP, Emili A, Wolozin B, Petrucelli L, Zhang YJ | Cell Rep |
| 2023/7/21 | Microcystin-LR induces lactate production disruption via altering the m(6)A modification in Sertoli cells. | Meng X, Li W, Wu Q, Gao Y, Zhang L | Ecotoxicol Environ Saf |
| 2023/7/25 | The yeast RNA methylation complex consists of conserved yet reconfigured components with m6A-dependent and independent roles. | Ensinck I, Maman A, Albihlal WS, Lassandro M, Salzano G, Sideri T, Howell SA, Calvani E, Patel H, Bushkin G, Ralser M, Snijders AP, Skehel M, Casa?±al A, Schwartz S, van Werven FJ | Elife |
| 2023/8/1 | RNA N(6)-methyladenosine profiling reveals differentially methylated genes associated with intramuscular fat metabolism during breast muscle development in chicken. | Yu B, Liu J, Cai Z, Wang H, Feng X, Zhang T, Ma R, Gu Y, Zhang J | Poult Sci |
| 2023/7/25 | Effect of acute PM(2.5) exposure on PTGS2 and RNA m6A modification. | Li Z, Su Q, Xu R, Peng J, Wang Z, Zhu X, Wei Y | Environ Pollut |
| 2023/7/26 | Downregulation of FTO in the hippocampus is associated with mental disorders induced by fear stress during pregnancy. | Jiang Y, Zhang T, Yang L, Du Z, Wang Q, Hou J, Liu Y, Song Q, Zhao J, Wu Y | Behav Brain Res |
| 2023/8/1 | METTL14 reverses liver fibrosis by inhibiting NOVA2 through an m6A-YTHDF2-dependent mechanism. | Hou X, Li Y, Song J, Peng L, Zhang W, Liu R, Yuan H, Feng T, Li J, Li W, Zhu C | Hepatol Commun |
| 2023/12/1 | Comprehensive analysis of m6A methylomes in idiopathic pulmonary arterial hypertension. | Huang T, Zeng Y, Yang Y, Fan H, Deng Y, Chen W, Liu J, Yang F, Li W, Xiao Y | Epigenetics |
| 2023/8/1 | Genetic and pharmacological inhibition of METTL3 alleviates renal fibrosis by reducing EVL m6A modification through an IGF2BP2-dependent mechanism. | Ni WJ, Zhou H, Lu H, Ma NN, Hou BB, Li W, Kong FX, Yu JT, Hou R, Jin J, Wen JG, Zhang T, Meng XM | Clin Transl Med |
| 2023/8/7 | EGR1 mediates METTL3/m(6)A/CHI3L1 to promote osteoclastogenesis in osteoporosis. | Wang C, Zhang X, Chen R, Zhu X, Lian N | Genomics |
| 2023/7/24 | Alterations of the m(6)A Methylation Induced by TGF-??2 in ARPE-19 Cells. | Zhao X, Li X, Li L, Zhang Y, Wu F, Yin R, Yuan M, Li X | Front Biosci (Landmark Ed) |
| 2023/8/10 | Mettl14-mediated m(6) A modification regulates the abnormal differentiation of small intestinal epithelial stem cells in diabetic state. | Shan TD, Han Y, Song MQ, Chen L | J Cell Physiol |
| 2023/7/25 | Molecular Mechanism of m6A Methylation Modification Genes METTL3 and FTO in Regulating Heat Stress in Sheep. | Chen B, Yuan C, Guo T, Liu J, Yang B, Lu Z | Int J Mol Sci |
| 2023/8/23 | ALKBH5 promotes hypopharyngeal squamous cell carcinoma apoptosis by targeting TLR2 in a YTHDF1/IGF2BP2-mediated manner. | Ye J, Wu Y, Chen Y, Ren Y, Jiang X, Dong Z, Zhang J, Jin M, Chen X, Wang Z, Xiao M | Cell Death Discov |
| 2023/7/31 | Erythroid-transdifferentiated myeloid cells promote portal vein tumor thrombus in hepatocellular carcinoma. | Zhu WH, Chen J, Huang RK, Zhang Y, Huang ZX, Pang XQ, Hu B, Yang Y, Li X | Theranostics |
| 2023/9/7 | Demethylase FTO-Mediated m6A Modification of lncRNA MEG3 Activates Neuronal Pyroptosis via NLRP3 Signaling in Cerebral Ischemic Stroke. | Yan H, Huang W, Rao J, Yan D, Yuan J | Mol Neurobiol |
| 2023/9/1 | Effects of Gestational Arsenic Exposures on Placental and Fetal Development in Mice: The Role of Cyr61 m6A. | Song YP, Lv JW, Zhang ZC, Qian QH, Fan YJ, Chen DZ, Zhang H, Xu FX, Zhang C, Huang Y, Wang H, Wei W, Xu DX | Environ Health Perspect |
| 2024/3/1 | The m6A regulator KIAA1429 stabilizes RAB27B mRNA and promotes the progression of chronic myeloid leukemia and resistance to targeted therapy. | Yao F, Zhong F, Jiang J, Cheng Y, Xu S, Liu J, Lin J, Zhang J, Li S, Li M, Xu Y, Huang B, Wang X | Genes Dis |
| 2023/9/7 | In vivo deuterium magnetic resonance imaging of xenografted tumors following systemic administration of deuterated water. | Brender JR, Assmann JC, Farthing DE, Saito K, Kishimoto S, Warrick KA, Maglakelidze N, Larus TL, Merkle H, Gress RE, Krishna MC, Buxbaum NP | Sci Rep |
| 2023/9/1 | Deubiquitinase USP19 modulates apoptotic calcium release and endoplasmic reticulum stress by deubiquitinating BAG6 in triple negative breast cancer. | Zhang X, Chen X, Qian F, Zhu Y, He G, Yang J, Wu X, Zhang H, Yu X, Liu X | Clin Transl Med |
| 2023/9/18 | VIRMA promotes neuron apoptosis via inducing m6A methylation of STK10 in spinal cord injury animal models. | Hong H, Xu G, Bao G, Zhang J, Chen C, Chen J, Wu C, Jiang J, Huang J, Huang H, Cui Z | CNS Neurosci Ther |
| 2023/9/21 | Disruption of CerS6-mediated sphingolipid metabolism by FTO deficiency aggravates ulcerative colitis. | Ma Y, Zhang X, Xuan B, Li D, Yin N, Ning L, Zhou YL, Yan Y, Tong T, Zhu X, Huang X, Hu M, Wang Z, Cui Z, Li H, Wang J, Fang JY, Liu R, Chen H, Hong J | Gut |
| 2023/9/22 | FTO-targeted siRNA delivery by MSC-derived exosomes synergistically alleviates dopaminergic neuronal death in Parkinson's disease via m6A-dependent regulation of ATM mRNA. | Geng Y, Long X, Zhang Y, Wang Y, You G, Guo W, Zhuang G, Zhang Y, Cheng X, Yuan Z, Zan J | J Transl Med |
| 2023/9/23 | METTL14-upregulated miR-6858 triggers cell apoptosis in keratinocytes of oral lichen planus through decreasing GSDMC. | Wang X, Li S, Song H, Ding Y, Gao R, Shi X, Li R, Ge X | Commun Biol |
| 2023/9/14 | METTL3 Promotes the Differentiation of Goat Skeletal Muscle Satellite Cells by Regulating MEF2C mRNA Stability in a m(6)A-Dependent Manner. | Zhao S, Cao J, Sun Y, Zhou H, Zhu Q, Dai D, Zhan S, Guo J, Zhong T, Wang L, Li L, Zhang H | Int J Mol Sci |
| 2023/9/15 | Hypoxia-induced m6A demethylase ALKBH5 promotes ovarian cancer tumorigenicity by decreasing methylation of the lncRNA RMRP. | Lyu Y, Wang Y, Ding H, Li P | Am J Cancer Res |
| 2023/9/26 | ZC3H13 Accelerates Keloid Formation by Mediating N6-methyladenosine Modification of HIPK2. | Fu M, Chen Y, Shi X | Biochem Genet |
| 2023/9/26 | Programmed Release METTL3-14 Inhibitor Microneedle Protects Myocardial Function by Reducing Drp1 m6A Modification-Mediated Mitochondrial Fission. | Huang B, Xie L, Ke M, Fan Y, Tan J, Ran J, Zhu C | ACS Appl Mater Interfaces |
| 2023/9/30 | Comprehensive analysis of aflatoxin B(1) biosynthesis in Aspergillus flavus via transcriptome-wide m6A methylome response to cycloleucine. | Liang L, Wang X, Lan H, Wei S, Lei Y, Zhang S, Zhai H, Hu Y, Lv Y | J Hazard Mater |
| 2023/10/4 | N6-methyladenosine (m6A) reader YTHDF2 accelerates endothelial cells ferroptosis in cerebrovascular atherosclerosis. | Li J, Zou C, Zhang Z, Xue F | Mol Cell Biochem |
| 2023/10/13 | Low RNA stability signifies strong expression regulatability of tumor suppressors. | Gao X, Yi Y, Lv J, Li Y, Arulsamy K, Babu SS, Bruno I, Zhang L, Cao Q, Chen K | Nucleic Acids Res |
| 2023/10/13 | YTHDF1 mitigates acute kidney injury via safeguarding m6A-methylated mRNAs in stress granules of renal tubules. | Yang W, Zhang M, Li J, Qu S, Zhou F, Liu M, Li L, Liu Z, Zen K | Redox Biol |
| 2023/10/16 | LncRNA FTO-IT1 promotes glycolysis and progression of hepatocellular carcinoma through modulating FTO-mediated N6-methyladenosine modification on GLUT1 and PKM2. | Wang F, Hu Y, Wang H, Hu P, Xiong H, Zeng Z, Han S, Wang D, Wang J, Zhao Y, Huang Y, Zhuo W, Lv G, Zhao G | J Exp Clin Cancer Res |
| 2023/12/1 | Isovitexin alleviates hepatic fibrosis by regulating miR-21-mediated PI3K/Akt signaling and glutathione metabolic pathway: based on transcriptomics and metabolomics. | Huang Y, Luo W, Chen S, Su H, Zhu W, Wei Y, Qiu Y, Long Y, Shi Y, Wei J | Phytomedicine |
| 2023/9/22 | Anti-resorption role of low-intensity pulsed ultrasound (LIPUS) during large-scale bone reconstruction using porous titanium alloy scaffolds through inhibiting osteoclast differentiation. | Luo L, Cao H, Zhou L, Zhang G, Wu L | Biomater Adv |
| 2023/9/23 | Comprehensive Analysis of the Transcriptome-Wide m6A Methylome in Shaziling Pig Testicular Development. | Chen C, Tang X, Yan S, Yang A, Xiang J, Deng Y, Yin Y, Chen B, Gu J | Int J Mol Sci |
| 2023/10/7 | ALKBH5 mediates silica particles-induced pulmonary inflammation through increased m6A modification of Slamf7 and autophagy dysfunction. | Yin H, Gu P, Xie Y, You X, Zhang Y, Yao Y, Yang S, Wang D, Chen W, Ma J | J Hazard Mater |
| 2023/9/26 | Overexpression of FTO inhibits excessive proliferation and promotes the apoptosis of human glomerular mesangial cells by alleviating FOXO6 m6A modification via YTHDF3-dependent mechanisms. | Zhuang X, Liu T, Wei L, Gao J | Front Pharmacol |
| 2023/10/17 | Phenethyl isothiocyanate inhibits metastasis potential of non-small cell lung cancer cells through FTO mediated TLE1 m(6)A modification. | Zhang QC, Qian YM, Ren YH, Chen MM, Cao LM, Zheng SJ, Li BB, Wang M, Wu X, Xu K | Acta Pharmacol Sin |
| 2023/10/17 | N6-methyladenosine reader protein IGF2BP1 suppresses CD8??‰+??‰T cells-mediated tumor cytotoxicity and apoptosis in colon cancer. | Peng Y, Zhang Z, Yang G, Dai Z, Cai X, Liu Z, Yun Q, Xu L | Apoptosis |
| 2023/9/27 | Comprehensive analysis of N6-methyladenosine-related RNA methylation in the mouse hippocampus after acquired hearing loss. | Zhou X, Jin L, Li Y, Wang Y, Li W, Shen X | BMC Genomics |
| 2023/10/19 | Targeting YTHDF2 inhibits tumorigenesis of diffuse large B-cell lymphoma through ACER2-mediated ceramide catabolism. | Chen X, Lu T, Ding M, Cai Y, Yu Z, Zhou X, Wang X | J Adv Res |
| 2023/10/19 | Hypoxia-induced neuronal activity in glioma patients polarizes microglia by potentiating RNA m6A demethylation. | Guo X, Qiu W, Li B, Qi Y, Wang S, Zhao R, Cheng B, Han X, Du H, Pan Z, Zhao S, Qiu J, Li G, Xue H | Clin Cancer Res |
| 2023/10/19 | ALKBH5 enhances lipid metabolism reprogramming by increasing stability of FABP5 to promote pancreatic neuroendocrine neoplasms progression in an m6A-IGF2BP2-dependent manner. | Chen J, Ye M, Bai J, Gong Z, Yan L, Gu D, Hu C, Lu F, Yu P, Xu L, Wang Y, Tian Y, Tang Q | J Transl Med |
| 2023/12/1 | Down-regulation of the FTO gene in follicular fluid of infertile women with ovarian endometriosis. | Li Y, Wang N, Jing Y, He J, Li F, Zhang X | Gynecol Endocrinol |
| 2023/10/14 | Nitric oxide inhibits FTO demethylase activity to regulate N6-methyladenosine mRNA methylation. | Kuschman HP, Palczewski MB, Hoffman B, Menhart M, Wang X, Glynn S, Islam ABMMK, Benevolenskaya EV, Thomas DD | Redox Biol |
| 2023/10/28 | Silencing METTL14 alleviates liver injury in non-alcoholic fatty liver disease by regulating mitochondrial homeostasis. | Wang W, Yan J, Han L, Zou ZL, Xu AL | Biomol Biomed |
| 2023/10/27 | METTL3-regulated m6A modification impairs the decidualization of endometrial stromal cells by regulating YTHDF2-mediated degradation of FOXO1 mRNA in endometriosis-related infertility. | Li X, Jin J, Long X, Weng R, Xiong W, Liang J, Liu J, Sun J, Cai X, Zhang L, Liu Y | Reprod Biol Endocrinol |
| 2023/10/26 | m6A methyltransferase METTL3 contributes to sympathetic hyperactivity post-MI via promoting TRAF6-dependent mitochondrial ROS production. | Yang P, Wang Y, Ge W, Jing Y, Hu H, Yin J, Xue M, Wang Y, Li X, Li X, Shi Y, Tan J, Li Y, Yan S | Free Radic Biol Med |
| 2023/11/1 | N6-methyladenosine methyltransferase METTL3 modulates the cell cycle of granulosa cells via CCND1 and AURKB in Haimen goats. | Liu Z, Zhou L, Li D, Lu H, Liu L, Mao W, Yu X, Fan Y, Huang Q, Wang F, Wan Y | FASEB J |
| 2023/10/29 | Hypothalamic FTO promotes high-fat diet-induced leptin resistance in mice through increasing CX3CL1 expression. | Liu S, Song S, Wang S, Cai TH, Qin L, Wang X, Zhu G, Wang H, Yang W, Fang C, Wei Y, Zhou F, Yu Y, Lin S, Peng S, Li L | J Nutr Biochem |
| 2023/11/1 | METTL3-mediated m6A methylation of C1qA regulates the Rituximab resistance of diffuse large B-cell lymphoma cells. | Li J, Zhu Z, Zhu Y, Li J, Li K, Zhong W | Cell Death Discov |
| 2023/10/31 | m6A modification associated with YTHDF1 is involved in Japanese encephalitis virus infection. | Li XH, Chen J, Ou YD, Zhong X, Hu JH, Sun RC, Lv YJ, Wei JC, Go YY, Zhou B | Vet Microbiol |
| 2023/11/5 | METTL14-m6A-FOXO3a axis regulates autophagy and inflammation in ankylosing spondylitis. | Chen Y, Wu Y, Fang L, Zhao H, Xu S, Shuai Z, Yu H, Cai G, Zhan HQ, Pan F | Clin Immunol |
| 2023/11/6 | SHMT2 regulates esophageal cancer cell progression and immune Escape by mediating m6A modification of c-myc. | Qiao Z, Li Y, Cheng Y, Li S, Liu S | Cell Biosci |
| 2023/11/14 | Neuronal activity promotes glioma progression by inducing proneural-to-mesenchymal transition in glioma stem cells. | Guo X, Qiu W, Wang C, Qi Y, Li B, Wang S, Zhao R, Cheng B, Han X, Du H, Gao Z, Pan Z, Zhao S, Li G, Xue H | Cancer Res |
| 2023/11/14 | Up-regulation of RNA m6A methyltransferase like-3 expression contributes to arsenic and benzo[a]pyrene co-exposure-induced cancer stem cell-like property and tumorigenesis. | Wang Z, Uddin MB, Wang PS, Liu Z, Barzideh D, Yang C | Toxicol Appl Pharmacol |
| 2023/11/16 | Increased m6A-RNA methylation and demethylase FTO suppression is associated with silica-induced pulmonary inflammation and fibrosis. | Xu Y, Wang L, Qian R, Zhao M, Chen X, Sun D, Wang Y, Cheng W, Chen Y, He Q, Dai Y, Yao Y | Toxicology |
| 2023/11/20 | Discovery of Pyrazolo[1,5-a]pyrimidine Derivative as a Novel and Selective ALKBH5 Inhibitor for the Treatment of AML. | Wang YZ, Li HY, Zhang Y, Jiang RX, Xu J, Gu J, Jiang Z, Jiang ZY, You QD, Guo XK | J Med Chem |
| 2023/11/25 | ALKBH5-mediated CHAC1 depletion promotes malignant progression and decreases cisplatin-induced oxidative stress in gastric cancer. | Chen C, Zhai E, Liu Y, Qian Y, Zhao R, Ma Y, Liu J, Huang Z, Chen J, Cai S | Cancer Cell Int |
| 2023/11/27 | WTAP-Mediated N6-Methyladenosine of RNAs Facilitate the Pathophysiology of Atopic Dermatitis. | Tan L, Chen X, Yan S, Guo A, Gao L, Zhou L, Zhou Y, Zeng J, Lu J | J Invest Dermatol |
| 2023/12/1 | N6-methyladenosine of TRIM27 enhances the stem cell-type phenotype of cisplatin-resistant colorectal cancer cells. | Zheng JQ, Zhan Y, Huang WJ, Chen ZY, Wu WH | Biochem Biophys Rep |
| 2023/11/29 | Electromagnetic field (50? Hz) enhance metabolic potential and induce adaptive/reprogramming response mediated by the increase of N6-methyladenosine RNA methylation in adipose-derived mesenchymal stem cells in vitro. | Sendera A, Adamczyk-Grochala J, Piku??a B, Cholewa M, Bana??-Z?…bczyk A | Toxicol In Vitro |
| 2023/9/21 | Targeting METTL3 reprograms the tumor microenvironment to improve cancer immunotherapy. | Yu H, Liu J, Bu X, Ma Z, Yao Y, Li J, Zhang T, Song W, Xiao X, Sun Y, Xiong W, Shi J, Dai P, Xiang B, Duan H, Yan X, Wu F, Zhang WC, Lin D, Hu H, Zhang H, Slack FJ, He HH, Freeman GJ, Wei W, Zhang J | Cell Chem Biol |
| 2023/12/1 | Autophagy activation is required for N6-methyladenosine modification to regulate ferroptosis in hepatocellular carcinoma. | Li Y, Guo M, Qiu Y, Li M, Wu Y, Shen M, Wang Y, Zhang F, Shao J, Xu X, Zhang Z, Zheng S | Redox Biol |
| 2023/12/2 | mTORC1 Mediates Biphasic Mechano-Response to Orchestrate Adhesion-Dependent Cell Growth and Anoikis Resistance. | Zhang C, Wang Y, Zhen Z, Li J, Su J, Wu C | Adv Sci (Weinh) |
| 2023/12/2 | RNA N6-methyladenosine-modified-binding protein YTHDF1 promotes prostate cancer progression by regulating androgen function-related gene TRIM68. | Nie Q, Wu X, Huang Y, Guo T, Kuang J, Du C | Eur J Med Res |
| 2023/12/2 | Exosome-shuttled FTO from BM-MSCs contributes to cancer malignancy and chemoresistance in acute myeloid leukemia by inducing m6A-demethylation: A nano-based investigation. | Kou R, Li T, Fu C, Jiang D, Wang Y, Meng J, Zhong R, Liang C, Dong M | Environ Res |
| 2023/12/4 | ALKBH5 protects against stroke by reducing endoplasmic reticulum stress-dependent inflammation injury via the STAT5/PERK/EIF2?±/CHOP signaling pathway in an m(6)A-YTHDF1-dependent manner. | Liu C, Chen H, Tao X, Li C, Li A, Wu W | Exp Neurol |
| 2023/11/1 | KIAA1429 facilitates progression of hepatocellular carcinoma by modulating m6A levels in HPN. | Meng Y, Yang W, Li J, Chai W | Heliyon |
| 2024/3/1 | METTL3-mediated lncRNA HOXD-AS1 stability regulates inflammation, and the migration and invasion of trophoblast cells via the miR-135a/ ??-TRCP axis. | Wang L, Shi L, Zhou B, Hong L, Gong H, Wu D | Noncoding RNA Res |
| 2023/12/12 | Phylogenetic and functional analyses of N6-methyladenosine RNA methylation factors in the wheat scab fungus Fusarium graminearum. | Kim H, Hu J, Kang H, Kim W | mSphere |
| 2023/12/14 | Transcriptome-wide N6-methyladenosine methylation profile of atherosclerosis in mice. | Zheng X, Zhou B, Li Y, Zhong H, Huang Z, Gu M | BMC Genomics |
| 2023/12/14 | DNA methylation regulates RNA m6A modification through transcription factor SP1 during the development of porcine somatic cell nuclear transfer embryos. | Zhang M, Zhai Y, An X, Li Q, Zhang D, Zhou Y, Zhang S, Dai X, Li Z | Cell Prolif |
| 2023/12/14 | ALKBH5 regulates ovarian cancer growth via demethylating long noncoding RNA PVT1 in ovarian cancer. | Li L, Chen J, Wang A, Yi K | J Cell Mol Med |
| 2023/12/18 | Celastrol suppresses human pancreatic cancer via m6A-YTHDF3-mediated downregulation of Claspin and Bcl-2. | Zhou Y, Zhuang H, Liu Y, Yin J, Wei X, Qiu Y, Tian Z, Miao T, Chen J, Li P, Xu X, Wu W, Li H, Shen W | Discov Oncol |
| 2023/12/11 | m6A-modified RIPK4 facilitates proliferation and cisplatin resistance in epithelial ovarian cancer. | Yin X, Zhao S, Zhang M, Xing J, Zhou J, Gao W, Chen L, Zhang Y, Lin L, Lu M, Li W, Shang J, Zhu X | Gynecol Oncol |
| 2023/12/21 | FTO-mediated m6A demethylation regulates GnRH expression in the hypothalamus via the PLC??3/Ca(2+)/CAMK signalling pathway. | Zang S, Yin X, Li P | Commun Biol |
| 2023/12/22 | N6-methyladenosine promotes aberrant redox homeostasis required for arsenic carcinogenesis by controlling the adaptation of key antioxidant enzymes. | Zhao T, Sun D, Long K, Xiong W, Man J, Zhang Q, Zhang Z | J Hazard Mater |
| 2023/12/28 | Putrescine promotes MMP9-induced angiogenesis in skeletal muscle through hydrogen peroxide/METTL3 pathway. | Hu C, Ji F, Lv R, Zhou H, Hou G, Xu T | Free Radic Biol Med |
| 2024/1/2 | N6 methyladenosine eraser FTO suppresses Staphylococcus aureus-induced ferroptosis of bone marrow mesenchymal stem cells to ameliorate osteomyelitis through regulating the MDM2/TLR4/SLC7A11 signaling pathway. | Song M, Lv K, Xu Z, Li J, Sun J, Shi J, Xu Y | Cell Biol Int |
| 2024/1/4 | MYH1G-AS is a chromatin-associated lncRNA that regulates skeletal muscle development in chicken. | Cai B, Ma M, Yuan R, Zhou Z, Zhang J, Kong S, Lin D, Lian L, Li J, Zhang X, Nie Q | Cell Mol Biol Lett |
| 2024/1/8 | ALKBH5 regulates paclitaxel resistance in NSCLC via inhibiting CEMIP-mediated EMT. | Gao L, Qiao L, Li Y, Jia L, Cui W, Yang J, Wu C, Wang L | Toxicol Appl Pharmacol |
| 2024/1/3 | Dietary selenomethionine reduced oxidative stress by resisting METTL3-mediated m6A methylation level of Nrf2 to ameliorate LPS-induced liver necroptosis in laying hens. | Li S, Wang Y, Xu A, Zhao B, Xia Y, He Y, Xue H, Li S | J Nutr Biochem |
| 2024/1/13 | METTL14 contributes to acute lung injury by stabilizing NLRP3 expression in an IGF2BP2-dependent manner. | Cao F, Chen G, Xu Y, Wang X, Tang X, Zhang W, Song X, Yang X, Zeng W, Xie J | Cell Death Dis |
| 2024/2/25 | Long-term MNNG exposure promotes gastric carcinogenesis by activating METTL3/m6A/miR1184 axis-mediated epithelial-mesenchymal transition. | Liu T, Feng YL, Wang RY, Yang S, Ge YL, Zhang TY, Li J, Li CY, Ruan Y, Luo B, Liang GY | Sci Total Environ |
| 2023/12/4 | METTL14 knockdown inhibits the pyroptosis in the sepsis-induced acute lung injury through regulating the m6A modification of NLRP3. | Gao J, Chen H, Zhang Y, Yu S, Wu Y, Wang Q, Yu Z | Exp Lung Res |
| 2024/1/20 | FTO protein regulates the TGF-?? signalling pathway through RNA N6-methyladenosine modification to induce unexplained recurrent spontaneous abortion. | Zhang J, Liu X, Gao Y | FEBS J |
| 2024/1/22 | Genome-wide screening of m6A profiling of cutaneous wound healing in diabetic mice. | Shen J, Chen H, Dai J | Mol Biol Rep |
| 2023/11/23 | Altered m6A RNA methylation governs denervation-induced muscle atrophy by regulating ubiquitin proteasome pathway. | Sun J, Zhou H, Chen Z, Zhang H, Cao Y, Yao X, Chen X, Liu B, Gao Z, Shen Y, Qi L, Sun H | J Transl Med |
| 2023/11/21 | Captive ERVWE1 triggers impairment of 5-HT neuronal plasticity in the first-episode schizophrenia by post-transcriptional activation of HTR1B in ALKBH5-m6A dependent epigenetic mechanisms. | Wu X, Liu L, Xue X, Li X, Zhao K, Zhang J, Li W, Yao W, Ding S, Jia C, Zhu F | Cell Biosci |
| 2023/10/26 | N6-methyladenosine demethylase FTO related to hyperandrogenism in PCOS via AKT pathway. | Jing YX, Li HX, Yue F, Li YM, Yu X, He JJ, Zhang XH | Gynecol Endocrinol |
| 2023/11/15 | Inhibition of METTL3 alleviated LPS-induced alveolar epithelial cell apoptosis and acute lung injury via restoring neprilysin expression. | Jia J, Yuan Y, He Y, Wasti B, Duan W, Chen Z, Li D, Sun W, Zeng Q, Ma L, Zhang X, Liu S, Zhang D, Liu L, Liu Q, Liang H, Wang G, Xiang X, Xiao B | Life Sci |
| 2023/12/13 | METTL3-mediated m6A methylation of TRAF5 inhibits lung adenocarcinoma cell metastasis via activation of the PI3K/AKT/NF-??B signaling pathway. | Zhou YF, Li JT, Zheng QL, Ren KL, Yi CC | Kaohsiung J Med Sci |
| 2023/11/28 | METTL3/YTHDF2 m6A axis mediates the progression of diabetic nephropathy through epigenetically suppressing PINK1 and mitophagy. | Wang F, Bai J, Zhang X, Wang D, Zhang X, Xue J, Chen H, Wang S, Chi B, Li J, Ma X | J Diabetes Investig |
| 2023/12/7 | EGFR promotes ALKBH5 nuclear retention to attenuate N6-methyladenosine and protect against ferroptosis in glioblastoma. | Lv D, Zhong C, Dixit D, Yang K, Wu Q, Godugu B, Prager BC, Zhao G, Wang X, Xie Q, Bao S, He C, Heiland DH, Rosenfeld MG, Rich JN | Mol Cell |
| 2024/1/29 | Regulation of ULK1 by WTAP/IGF2BP3 axis enhances mitophagy and progression in epithelial ovarian cancer. | Wang J, Zheng F, Wang D, Yang Q | Cell Death Dis |
| 2024/1/22 | Benchmarking of computational methods for m6A profiling with Nanopore direct RNA sequencing. | Maestri S, Furlan M, Mulroney L, Coscujuela Tarrero L, Ugolini C, Dalla Pozza F, Leonardi T, Birney E, Nicassio F, Pelizzola M | Brief Bioinform |
| 2024/1/31 | Lactylation-driven FTO targets CDK2 to aggravate microvascular anomalies in diabetic retinopathy. | Chen X, Wang Y, Wang JN, Zhang YC, Zhang YR, Sun RX, Qin B, Dai YX, Zhu HJ, Zhao JX, Zhang WW, Ji JD, Yuan ST, Shen QD, Liu QH | EMBO Mol Med |
| 2024/2/1 | Targeting the m(6)A RNA methyltransferase METTL3 attenuates the development of kidney fibrosis. | Jung HR, Lee J, Hong SP, Shin N, Cho A, Shin DJ, Choi JW, Kim JI, Lee JP, Cho SY | Exp Mol Med |
| 2024/2/5 | METTL3-m6A-SIRT1 axis affects autophagic flux contributing to PM(2.5)-induced inhibition of testosterone production in Leydig cells. | Jiang L, Lin X, Jiang J, Qiu C, Zheng S, Zhao N, Shu Z, Qian Y, Qiu L | Sci Total Environ |
| 2024/2/5 | Linc-smad7 is involved in the regulation of lipid synthesis in mouse mammary epithelial cells. | Fang X, Chen J, Meng F, Chen F, Chen X, Wang Y, Fang X, Zhang C, Song C | Int J Biol Macromol |
| 2024/2/7 | METTL14 enhances the m6A modification level of lncRNA MSTRG.292666.16 to promote the progression of non-small cell lung cancer. | Ji X, Wan X, Sun H, Deng Q, Meng S, Xie B, Zhou S | Cancer Cell Int |
| 2024/1/1 | Epitranscriptomic regulation in fasting hearts: implications for cardiac health. | Benak D, Holzerova K, Hrdlicka J, Kolar F, Olsen M, Karelson M, Hlavackova M | RNA Biol |
| 2024/2/9 | Acute/chronic triclosan exposure induces downregulation of m6A-RNA methylation modification via mettl3 suppression and elicits developmental and immune toxicity to zebrafish. | Qian Q, Pu Q, Li X, Liu X, Ni A, Han X, Wang Z, Wang X, Yan J, Wang H | Chemosphere |
| 2024/2/12 | Transcriptome-wide profiling identifies colon cancer-associated m6A transcripts and potential RNA methyl modifiers. | Ramasamy D, Thippannah M, Maharajan HRP, Balaiah M, Seshadri RA, Kodous AS, Herceg Z, Mehta A, Rao AKDM, Mani S | Mol Biol Rep |
| 2024/2/13 | Exposure to bisphenol A affects transcriptome-wide N6-methyladenine methylation in ovarian granulosa cells. | Zhang Y, Yan C, Xie Q, Wu B, Zhang Y | Ecotoxicol Environ Saf |
| 2024/2/14 | Multigenerational paternal obesity enhances the susceptibility to male subfertility in offspring via Wt1 N6-methyladenosine modification. | Xiong YW, Zhu HL, Zhang J, Geng H, Tan LL, Zheng XM, Li H, Fan LL, Wang XR, Zhang XD, Wang KW, Chang W, Zhang YF, Yuan Z, Duan ZL, Cao YX, He XJ, Xu DX, Wang H | Nat Commun |
| 2024/2/10 | HIF-1?±/m6A/NF-??B/CCL3 axis-mediated immunosurveillance participates in low level benzene-related erythrohematopoietic development toxicity. | Cong X, Li X, Xu K, Yin L, Liang G, Sun R, Pu Y, Zhang J | Environ Int |
| 2024/2/16 | The m6A methylation and expression profiles of mouse neural stem cells after hypoxia/reoxygenation. | Zhang S, Cui K, Li Y, Fan Y, Wang D, Yao X, Fang B | Stem Cell Res Ther |
| 2024/2/16 | The m6A reader IGF2BP1 attenuates the stability of RPL36 and cell proliferation to mediate benzene hematotoxicity by recognizing m6A modification. | Wang J, Guo X, Chen Y, Zhang W, Ren J, Gao A | Toxicology |
| 2024/2/16 | RNA m6A modification regulates L1 retrotransposons in human spermatogonial stem cell differentiation in vitro and in vivo. | Li Z, Fang F, Zafar MI, Wu X, Liu X, Tan X, Luo J, Ye Z, Xiong C, Li H | Cell Mol Life Sci |
| 2024/2/17 | N6-methyladenosine modification of the mRNA for a key gene in purine nucleotide metabolism regulates virus proliferation in an insect vector. | Zhu M, Wu N, Zhong J, Chen C, Liu W, Ren Y, Wang X, Jin H | Cell Rep |
| 2024/2/19 | High estrogen during ovarian stimulation induced loss of maternal imprinted methylation that is essential for placental development via overexpression of TET2 in mouse oocytes. | Lu X, Mao J, Qian C, Lei H, Mu F, Sun H, Yan S, Fang Z, Lu J, Xu Q, Dong J, Su D, Wang J, Jin N, Chen S, Wang X | Cell Commun Signal |
| 2024/2/1 | LRPPRC promotes glycolysis by stabilising LDHA mRNA and its knockdown plus glutamine inhibitor induces synthetic lethality via m(6) A modification in triple-negative breast cancer. | Yu Y, Deng H, Wang W, Xiao S, Zheng R, Lv L, Wang H, Chen J, Zhang B | Clin Transl Med |
| 2024/2/26 | Redox regulation of m6A methyltransferase METTL3 in ??-cells controls the innate immune response in type 1 diabetes. | F De Jesus D, Zhang Z, Brown NK, Li X, Xiao L, Hu J, Gaffrey MJ, Fogarty G, Kahraman S, Wei J, Basile G, Rana TM, Mathews C, Powers AC, Parent AV, Atkinson MA, Dhe-Paganon S, Eizirik DL, Qian WJ, He C, Kulkarni RN | Nat Cell Biol |
| 2024/2/15 | The m(6)A demethylase fat mass and obesity-associated protein mitigates pyroptosis and inflammation in doxorubicin-induced heart failure via the toll-like receptor 4/NF-??B pathway. | Tu W, Huang X, Liu S, Zhan Y, Cai X, Shao L | Cardiovasc Diagn Ther |
| 2024/3/5 | N(6)-methyladenosine demethyltransferase FTO mediated m(6)A modification of estrogen receptor alpha in non-small cell lung cancer tumorigenesis. | Xu X, Qiu S, Zeng B, Huang Y, Wang X, Li F, Yang Y, Cao L, Zhang X, Wang J, Ma L | Oncogene |
| 2024/3/6 | D-2-HG Inhibits IDH1mut Glioma Growth via FTO Inhibition and Resultant m6A Hypermethylation. | Pianka ST, Li T, Prins TJ, Eldred BSC, Kevan BM, Liang H, Zapanta Rinonos S, Kornblum HI, Nathanson DA, Pellegrini M, Liau LM, Nghiemphu PL, Cloughesy TF, Lai A | Cancer Res Commun |
| 2024/3/6 | The RNA m(6)A reader IGF2BP3 regulates NFAT1/IRF1 axis-mediated anti-tumor activity in gastric cancer. | Ge L, Rui Y, Wang C, Wu Y, Wang H, Wang J | Cell Death Dis |
| 2024/3/11 | Arginine methylation of ALKBH5 by PRMT6 promotes breast tumorigenesis via LDHA-mediated glycolysis. | Han X, Ren C, Jiang A, Sun Y, Lu J, Ling X, Lu C, Yu Z | Front Med |
| 2024/3/14 | Obesity-induced downregulation of miR-192 exacerbates lipopolysaccharide-induced acute lung injury by promoting macrophage activation. | Wu S, Tang W, Liu L, Wei K, Tang Y, Ma J, Li H, Ao Y | Cell Mol Biol Lett |
| 2024/3/15 | The antagonistic effect of FTO on METTL14 promotes AKT3 m(6)A demethylation and the progression of esophageal cancer. | Wei R, Zhao F, Kong L, Pu Y, Li Y, Zang C | J Cancer Res Clin Oncol |
| 2024/3/30 | Dynamics of N6-methyladenosine modification during Alzheimer's disease development. | Gao S, Wang Y, Li X, Liang Y, Jin Z, Yang B, Yuan TF, Tian H, Peng B, Rao Y | Heliyon |
| 2024/2/25 | WTAP Mediated N6-methyladenosine RNA Modification of ELF3 Drives Cellular Senescence by Upregulating IRF8. | Zhou L, Zhong Y, Wang F, Guo Y, Mao R, Xie H, Zhang Y, Li J | Int J Biol Sci |
| 2024/3/15 | MiR-186-5p prevents hepatocellular carcinoma progression by targeting methyltransferase-like 3 that regulates m6A-mediated stabilization of follistatin-like 5. | Ma S, Chen F, Lin C, Sun W, Wang D, Zhou S, Chang S, Lu Z, Zhang D | Heliyon |
| 2024/3/5 | N(6)-methyladenosine levels in peripheral blood RNA: a potential diagnostic biomarker for colorectal cancer. | Cao Y, Zhang C, Chen J, Ren J, Li X, Zhang Y, Huang B, Xu Y, Dong L | Cancer Cell Int |
| 2024/3/19 | Geniposide reduced oxidative stress-induced apoptosis in HK-2 cell through PI3K/AKT3/FOXO1 by m6A modification. | Cheng W, Tan L, Yu S, Song J, Li Z, Peng X, Wei Q, He Z, Zhang W, Yang X | Int Immunopharmacol |
| 2024/3/19 | Geniposide reduced oxidative stress-induced apoptosis in HK-2 cell through PI3K/AKT3/FOXO1 by m6A modification. | Cheng W, Tan L, Yu S, Song J, Li Z, Peng X, Wei Q, He Z, Zhang W, Yang X | Int Immunopharmacol |
| 2024/3/28 | ELAVL2 loss promotes aggressive mesenchymal transition in glioblastoma. | Kim Y, You JH, Ryu Y, Park G, Lee U, Moon HE, Park HR, Song CW, Ku JL, Park SH, Paek SH | NPJ Precis Oncol |
| 2024/3/29 | Classical swine fever virus non-structural protein 5B hijacks host METTL14-mediated m6A modification to counteract host antiviral immune response. | Chen J, Song HX, Hu JH, Bai JS, Li XH, Sun RC, Zhao BQ, Li MZ, Zhou B | PLoS Pathog |
| 2023/2/16 | Redox Regulation of m (6) A Methyltransferase METTL3 in Human ??-cells Controls the Innate Immune Response in Type 1 Diabetes. | De Jesus DF, Zhang Z, Brown NK, Li X, Gaffrey MJ, Kahraman S, Wei J, Hu J, Basile G, Xiao L, Rana TM, Mathews C, Powers AC, Atkinson MA, Eizirik DL, Dhe-Paganon S, Parent AV, Qian WJ, He C, Kulkarni RN | bioRxiv |
| 2023/2/24 | Vitamin C and Transferrin Reduce RNA Methylation in Mouse Embryonic Stem Cells. | Brandt G, Sedivy LJ, Mitchell M, Phiel CJ | bioRxiv |
| 2023/2/24 | Mouse Embryonic Stem Cell Pluripotency Factors Regulate RNA Methylation. | Sedivy LJ, Brandt G, Martin AL, Abroe HM, Phiel CJ | bioRxiv |
| 2023/11/22 | METTL3 alters capping enzyme expression and its activity on ribosomal proteins. | Del Valle-Morales D, Romano G, Le P, Saviana M, Brown R, Micalo L, Li H, La Ferlita A, Nigita G, Nana-Sinkam P, Acunzo M | bioRxiv |
| 2023/2/16 | Redox Regulation of m (6) A Methyltransferase METTL3 in Human ??-cells Controls the Innate Immune Response in Type 1 Diabetes. | De Jesus DF, Zhang Z, Brown NK, Li X, Gaffrey MJ, Kahraman S, Wei J, Hu J, Basile G, Xiao L, Rana TM, Mathews C, Powers AC, Atkinson MA, Eizirik DL, Dhe-Paganon S, Parent AV, Qian WJ, He C, Kulkarni RN | bioRxiv |
| 2023/2/24 | Vitamin C and Transferrin Reduce RNA Methylation in Mouse Embryonic Stem Cells. | Brandt G, Sedivy LJ, Mitchell M, Phiel CJ | bioRxiv |
| 2023/2/24 | Mouse Embryonic Stem Cell Pluripotency Factors Regulate RNA Methylation. | Sedivy LJ, Brandt G, Martin AL, Abroe HM, Phiel CJ | bioRxiv |
| 2023/11/22 | METTL3 alters capping enzyme expression and its activity on ribosomal proteins. | Del Valle-Morales D, Romano G, Le P, Saviana M, Brown R, Micalo L, Li H, La Ferlita A, Nigita G, Nana-Sinkam P, Acunzo M | bioRxiv |
| 2024/4/1 | Engagement of N(6)-methyladenisine methylation of Gng4 mRNA in astrocyte dysfunction regulated by CircHECW2. | Bai Y, Chang D, Ren H, Ju M, Wang Y, Chen B, Li H, Liu X, Li D, Huo X, Guo X, Tong M, Tan Y, Yao H, Han B | Acta Pharm Sin B |
| 2024/4/4 | Ginger inhibits the invasion of ovarian cancer cells SKOV3 through CLDN7, CLDN11 and CD274 m6A methylation modifications. | Zhang X, Zhang H, Zhu L, Xia L | BMC Complement Med Ther |
| 2024/4/15 | METTL3 mediates SOX5 m6A methylation in bronchial epithelial cells to attenuate Th2 cell differentiation in T2 asthma. | Chen Z, Shang Y, Zhang X, Duan W, Li J, Zhu L, Ma L, Xiang X, Jia J, Ji X, Gong S | Heliyon |
| 2024/4/1 | ALKBH5-mediated m6A demethylation of pri-miR-199a-5p exacerbates myocardial ischemia/reperfusion injury by regulating TRAF3-mediated pyroptosis. | Li J, Wang Z, Tan H, Tang M | J Biochem Mol Toxicol |
| 2024/4/12 | Inhibition of METTL3 ameliorates doxorubicin-induced cardiotoxicity through suppression of TFRC-mediated ferroptosis. | Wu L, Du Y, Wang L, Zhang Y, Ren J | Redox Biol |
| 2024/4/16 | Cancer-associated fibroblasts-derived exosomal METTL3 promotes the proliferation, invasion, stemness and glutaminolysis in non-small cell lung cancer cells by eliciting SLC7A5 m6A modification. | Fan Y, Yu Y | Hum Cell |
| 2024/4/22 | Inhibition of METTL3 in macrophages provides protection against intestinal inflammation. | Yin H, Ju Z, Zhang X, Zuo W, Yang Y, Zheng M, Zhang X, Liu Y, Peng Y, Xing Y, Yang A, Zhang R | Cell Mol Immunol |
| 2024/9/1 | ALKBH5 regulates arginase 1 expression in MDSCs and their immunosuppressive activity in tumor-bearing host. | Feng L, Li M, Ma J, Wang W, Wang S, Mao Z, Zhang Y | Noncoding RNA Res |
| 2024/4/29 | Landscape of transcriptome-wide m(6)A modification in diabetic liver reveals rewiring of PI3K-Akt signaling after physical exercise. | Chen C, Jiang C, Lin T, Hu Y, Wu H, Xiang Q, Yang M, Wang S, Han X, Tao J | Acta Physiol (Oxf) |
| 2024/4/24 | Hirschsprung's disease: m6A methylase VIRMA suppresses cell migration and proliferation by regulating GSK3??. | Yang Y, Zhang M, Li N, Wang C, Yang H, Hou X, Yang J, Fan K, Yang L, Wu K | Pediatr Res |
| 2024/4/24 | ZC3H13 promotes ITGA6 m(6)A modification for chronic obstructive pulmonary disease progression. | Xie B, Dai Z, Jiang C, Gao X, Yang S, Peng M, Chen Q, Chen X | Cell Signal |
| 2024/4/27 | Positive GLI1/INHBA feedback loop drives tumor progression in gastric cancer. | Sun J, Zhu W, Luan M, Xing Y, Feng Z, Zhu J, Ma X, Wang Y, Jia Y | Cancer Sci |
| 2024/4/27 | The combination of methionine adenosyltransferase 2A inhibitor and methyltransferase like 3 inhibitor promotes apoptosis of non-small cell lung cancer cells and produces synergistic anti-tumor activity. | Xuan YF, Lu S, Ou YJ, Bao XB, Huan XJ, Song SS, Miao ZH, Wang YQ | Biochem Biophys Res Commun |
| 2024/1/31 | ELABELA-APJ Axis Enhances Mesenchymal Stem Cell Proliferation and Migration via the METTL3/PI3K/AKT Pathway. | Xu D, Fu J, Liu X, Hong Y, Chen X, Li S, Hou J, Zhang K, Zhou C, Zeng C, Zheng G, Wu H, Wang T | Acta Naturae |
| 2024/5/13 | N6-methyladenosine modification of KLF2 may contribute to endothelial-to-mesenchymal transition in pulmonary hypertension. | Kang K, Xiang J, Zhang X, Xie Y, Zhou M, Zeng L, Zhuang J, Kuang J, Lin Y, Hu B, Xiong Q, Yin Q, Su Q, Liao X, Wang J, Niu Y, Liu C, Tian J, Gou D | Cell Mol Biol Lett |
| 2024/4/22 | Verbascoside inhibits oral squamous cell carcinoma cell proliferation, migration, and invasion by the methyltransferase 3-mediated microRNA-31-5p/homeodomain interacting protein kinase 2 axis. | Huang Y, Wu W, Zhang X | Arch Oral Biol |
| 2024/4/26 | Roseburia intestinalis Supplementation Could Reverse the Learning and Memory Impairment and m6A Methylation Modification Decrease Caused by 27-Hydroxycholesterol in Mice. | Sun X, Zhou C, Ju M, Feng W, Guo Z, Qi C, Yang K, Xiao R | Nutrients |
| 2024/5/15 | circATAD2 mitigates CD8(+) T cells antitumor immune surveillance in breast cancer via IGF2BP3/m(6)A/PD-L1 manner. | Zhang Z, Huo W, Li J | Cancer Immunol Immunother |
| 2024/5/23 | Antiretroviral Therapy Suppresses RNA N(6)-Methyladenosine Modification in Peripheral Blood Mononuclear Cells from HIV-1-Infected Individuals. | Mishra T, Phillips S, Maldonado C, Stapleton JT, Wu L | AIDS Res Hum Retroviruses |
| 2024/4/17 | Epigenetic alterations in creatine transporter deficiency: a new marker for dodecyl creatine ester therapeutic efficacy monitoring. | Broca-Brisson L, Disdier C, Harati R, Hamoudi R, Mabondzo A | Front Neurosci |
| 2024/5/21 | Astrocytic ALKBH5 in stress response contributes to depressive-like behaviors in mice. | Guo F, Fan J, Liu JM, Kong PL, Ren J, Mo JW, Lu CL, Zhong QL, Chen LY, Jiang HT, Zhang C, Wen YL, Gu TT, Li SJ, Fang YY, Pan BX, Gao TM, Cao X | Nat Commun |
| 2024/5/22 | Hypoxia-induced downregulation of RNA m(6)A protein machinery in the naked mole-rat heart. | Ingelson-Filpula WA, Kadamani KL, Ojaghi M, Pamenter ME, Storey KB | Biochimie |
| 2024/5/1 | Phosphorylated SHMT2 Regulates Oncogenesis Through m(6)A Modification in Lung Adenocarcinoma. | Han T, Wang Y, Cheng M, Hu Q, Wan X, Huang M, Liu Y, Xun W, Xu J, Wang L, Luo R, Yuan Y, Wang K, Wang J | Adv Sci (Weinh) |
| 2024/6/3 | METTL3-mediated pre-miR-665/DLX3 m(6)A methylation facilitates the committed differentiation of stem cells from apical papilla. | Gu T, Guo R, Fang Y, Xiao Y, Chen L, Li N, Ge XK, Shi Y, Wu J, Yan M, Yu J, Li Z | Exp Mol Med |
| 2024/6/3 | The m(6)A writer RBM15 drives the growth of triple-negative breast cancer cells through the stimulation of serine and glycine metabolism. | Park SH, Ju JS, Woo H, Yun HJ, Lee SB, Kim SH, Gy?‘rffy B, Kim EJ, Kim H, Han HD, Eyun SI, Lee JH, Park YY | Exp Mol Med |
| 2024/5/31 | Profling of m(6)A methylation in porcine intramuscular adipocytes and unravelling PHKG1 repress porcine intramuscular lipid deposition in an m(6)A-dependent manner. | Chao M, Wang M, Han H, Liu Y, Sun X, Tian T, Pang W, Cai R | Int J Biol Macromol |
| 2024/6/7 | METTL3 promotes the progression of osteosarcoma through the N6-methyladenosine modification of MCAM via IGF2BP1. | Song D, Wang Q, Yan Z, Su M, Zhang H, Shi L, Fan Y, Zhang Q, Yang H, Zhang D, Liu Q | Biol Direct |
| 2024/6/7 | The histone methyltransferase SETD2 regulates HIV expression and latency. | Bussey-Sutton CR, Ward A, Fox JA, Turner AW, Peterson JJ, Emery A, Longoria AR, Gomez-Martinez I, Jones C, Hepperla A, Margolis DM, Strahl BD, Browne EP | PLoS Pathog |
| 2024/6/12 | N6-methyladenosine-driven miR-143/145-KLF4 circuit orchestrates the phenotypic switch of pulmonary artery smooth muscle cells. | Kang K, Sun C, Li H, Liu X, Deng J, Chen S, Zeng L, Chen J, Liu X, Kuang J, Xiang J, Cheng J, Liao X, Lin M, Zhang X, Zhan C, Liu S, Wang J, Niu Y, Liu C, Liang C, Zhu J, Liang S, Tang H, Gou D | Cell Mol Life Sci |
| 2024/6/13 | ZFHX3 acts as a tumor suppressor in prostate cancer by targeting FTO-mediated m(6)A demethylation. | Hu Q, Yin J, Zhao S, Wang Y, Shi R, Yan K, Huang S | Cell Death Discov |
| 2024/6/12 | m6A reduction relieves FUS-associated ALS granules. | Di Timoteo G, Giuliani A, Setti A, Biagi MC, Lisi M, Santini T, Grandioso A, Mariani D, Castagnetti F, Perego E, Zappone S, Lattante S, Sabatelli M, Rotili D, Vicidomini G, Bozzoni I | Nat Commun |
| 2024/3/20 | 20(R)-Panaxatriol enhances METTL3-mediated m(6)A modification of STUB1 to inhibit autophagy and exert antitumor effects in Triple-Negative Breast Cancer cells. | Li Y, Luo B, Lin X, Bai D, Li L, Gao D, Li X, Zhong X, Wei Y, Yang L, Zhu X, Han L, Tian H, Zhang R, Wang P | Phytomedicine |
| 2024/5/16 | Histone lactylation-regulated METTL3 promotes ferroptosis via m6A-modification on ACSL4 in sepsis-associated lung injury. | Wu D, Spencer CB, Ortoga L, Zhang H, Miao C | Redox Biol |
| 2024/6/17 | FTO alleviated ferroptosis in septic cardiomyopathy via mediating the m6A modification of BACH1. | Zeng H, Xu J, Wu R, Wang X, Jiang Y, Wang Q, Guo J, Xiao F | Biochim Biophys Acta Mol Basis Dis |
| 2024/6/20 | KIAA1429 promotes gastric cancer progression by destabilizing RASD1 mRNA in an m(6)A-YTHDF2-dependent manner. | Ren M, Pan H, Zhou X, Yu M, Ji F | J Transl Med |
| 2024/6/15 | METTL14 is Involved in TNF-?±-Induced Inflammation in Colorectal Epithelial Cells via Autophagy Modulation. | Wu W, Yang H, Li X, Zhou Z, Tan W, Quan JH | Appl Biochem Biotechnol |
| 2024/6/26 | YTHDC2 mediated RNA m(6)A modification contributes to PM(2.5)-induced hepatic steatosis. | Yan Z, Zhang Y, Nan N, Ji S, Lan S, Qin G, Sang N | J Hazard Mater |
| 2024/6/27 | WTAP/YTHDF1-mediated m(6)A modification amplifies IFN-??-induced immunosuppressive properties of human MSCs. | Chen Q, Ao L, Zhao Q, Tang L, Xiong Y, Yuan Y, Wu X, Xing W, Li Z, Guo W, Liang H, Zheng S, Lian Q, Lu D, Wan W, Xu X | J Adv Res |
| 2024/6/29 | m6A-YTHDF1 Mediated Regulation of GRIN2D in Bladder Cancer Progression and Aerobic Glycolysis. | Le M, Qing M, Zeng X, Cheng S | Biochem Genet |
| 2024/7/2 | METTL14-mediated Bim mRNA m6A modification augments osimertinib sensitivity in EGFR-mutant NSCLC cells. | Fan S, Lv X, Zhang C, Zeng B, Liang Y, Chen D, Xu Z, Li P, Wu S, Liu H, Luo K, Liu Z, Yi Y | Mol Cancer Res |
| 2024/7/7 | ?±-Ketoglutarate plays an inflammatory inhibitory role by regulating scavenger receptor class a expression through N6-methyladenine methylation during sepsis. | Liang G, Hu JY, Liu RJ, Chao YP, Hu YF, Zheng H, Pan XY, Li YJ, Gong YH, Lin C, Lin JH, Wang JD, Li TX, Pan JP, Guo DY | Eur J Immunol |
| 2024/7/18 | IGF2BP3 suppresses ferroptosis in lung adenocarcinoma by m6A-dependent regulation of TFAP2A to transcriptionally activate SLC7A11/GPX4. | Li P, Chu D, Ding G, Qin D, Bu Y, Tian B | Mol Cell Biochem |
| 2024/7/19 | Global DNA and RNA Methylation Signature in Response to Antipsychotic Treatment in First-Episode Schizophrenia Patients. | Angelin M, Gopinath P, Raghavan V, Thara R, Ahmad F, Munirajan AK, Sudesh R | Neuropsychiatr Dis Treat |
| 2024/7/23 | WTAP/IGF2BP3 mediated m6A modification of the EGR1/PTEN axis regulates the malignant phenotypes of endometrial cancer stem cells. | Wang B, Wang Y, Wang W, Wang Z, Zhang Y, Pan X, Wen X, Leng H, Guo J, Ma XX | J Exp Clin Cancer Res |
| 2024/8/1 | METTL3/IGF2BP1 influences the development of non-small-cell lung cancer by mediating m6A methylation modification of TRPV1. | Bai W, Xiao G, Xie G, Chen Z, Xu X, Zeng J, Xie J | Thorac Cancer |
| 2024/8/1 | 17β-estradiol promotes the progression of temporomandibular joint osteoarthritis by regulating the FTO/IGF2BP1/m6A-NLRC5 axis | Xue X, Li C, Chen S, Zheng Y, Zhang F, Xu Y | Immun Inflamm Dis |
| 2024/8/2 | N(6)-methyladenosine-modified SRPK1 promotes aerobic glycolysis of lung adenocarcinoma via PKM splicing. | Wang A, Zeng Y, Zhang W, Zhao J, Gao L, Li J, Zhu J, Liu Z, Huang JA | Cell Mol Biol Lett |
| 2024/8/2 | Fluoride exposure-induced gut microbiota alteration mediates colonic ferroptosis through N(6)-methyladenosine (m(6)A) mediated silencing of SLC7A11. | Huang H, Lin Y, Xin J, Sun N, Zhao Z, Wang H, Duan L, Zhou Y, Liu X, Fang J, Jing B, Pan K, Zeng Y, Zeng D, Li H, Ma H, Bai Y, Wei L, Ni X | Ecotoxicol Environ Saf |
| 2024/8/5 | Anticancer effects of Erzhimaoling decoction in high-grade serous ovarian cancer in vitro and in vivo. | Yang L, Liu J, Zhang J, Shao F, Jin Y, Xing J, Zhou H, Yu A | Eur J Med Res |
| 2024/8/7 | N6-methyladenosine RNA modification regulates photoperiod sensitivity in cotton. | He Y, Si Z, Mei G, Cheng Y, Zhang J, Jiang T, Chen J, Xiong H, Zhang T, Hu Y | Plant Physiol |
| 2024/8/6 | ZC3H13-Mediated m6A Modification Ameliorates Acute Myocardial Infarction through Preventing Inflammation, Oxidative Stress and Ferroptosis by Targeting lncRNA93358. | Cai J, Wang X, Wang Z, Sheng S, Tang F, Zhang Z | Inflammation |
| 2024/8/13 | METTL14-mediated m6A mRNA modification of G6PD promotes lung adenocarcinoma. | Wu W, Li M, Wu Y, Wei Q, Yu N | Cell Death Discov |
| 2024/8/13 | Identification of an m6A Natural Inhibitor, Lobeline, That Reverses Lenvatinib Resistance in Hepatocellular Tumors. | Zhao L, Ma H, Jiang Y, Li Y, Qiao L, Chen Y, Jiang X, Wang L, Wang S, Fan X | J Nat Prod |
| 2024/8/9 | KHSRP Stabilizes m6A-Modified Transcripts to Activate FAK Signaling and Promote Pancreatic Ductal Adenocarcinoma Progression. | Xu Z, Zhou Y, Liu S, Zhao H, Chen Z, Li R, Li M, Huang X, Deng S, Zeng L, Zhao S, Zhang S, He X, Liu J, Xue C, Bai R, Zhuang L, Zhou Q, Chen R, Lin D, Zheng J, Zhang J | Cancer Res |
| 2024/8/12 | M6A RNA methylation-mediated TUG1 stability maintains mitochondrial homeostasis during kidney aging by epigenetically regulating PGC1-?± expression. | Zhu Y, Yang B, Chen S, Chen G, Zeng X, Min H, Xu L | Antioxid Redox Signal |
| 2024/9/15 | m(6)A-mediated HDAC9 upregulation promotes particulate matter-induced airway inflammation via epigenetic control of DUSP9-MAPK axis and acts as an inhaled nanotherapeutic target. | Zeng Y, Bai X, Zhu G, Zhu M, Peng W, Song J, Cai H, Ye L, Chen C, Song Y, Jin M, Zhang XQ, Wang J | J Hazard Mater |
| 2024/8/19 | METTL3 in cancer-associated fibroblasts-derived exosomes promotes the proliferation and metastasis and suppresses ferroptosis in colorectal cancer by eliciting ACSL3 m6A modification. | Ren H, Wang M, Ma X, An L, Guo Y, Ma H | Biol Direct |
| 2024/8/19 | N6-methyladenosine RNA methyltransferase CpMTA1 mediates CpAphA mRNA stability through a YTHDF1-dependent m6A modification in the chestnut blight fungus. | Zhao L, Wei X, Chen F, Yuan L, Chen B, Li R | PLoS Pathog |
| 2024/8/16 | Sirt1 m6A modification-evoked Leydig cell senescence promotes Cd-induced testosterone decline. | Zheng XM, Zhang XD, Tan LL, Zhang J, Wang TT, Ling Q, Wang H, Ouyang KW, Wang KW, Chang W, Li H, Zhu HL, Xiong YW, Wang H | Ecotoxicol Environ Saf |
| 2024/8/21 | ALKBH5 governs human endoderm fate by regulating the DKK1/4-mediated Wnt/??-catenin activation. | Liang Z, Huang T, Li W, Ma Z, Wang K, Zhai Z, Fan Y, Fu Y, Wang X, Qin Y, Wang B, Zhao C, Kuang J, Pei D | Nucleic Acids Res |
| 2024/8/27 | WTAP promotes fibroblast-like synoviocyte pyroptosis in Rheumatoid arthritis by upregulating N6-methyladenosine modification of NLRP3. | Liu X, Xia Z, Liu L, Ren D | J Bioenerg Biomembr |
| 2024/8/31 | Methyltransferase-Like 3-Driven N6-Methyladenosine Modification of RBPJ Promotes Vascular Remodeling in Pulmonary Hypertension. | Du Q, Zhang C, Qu T, Zhou X, Liu Y, Chen Z, Shen Z, Chen P, Zhang R | Am J Pathol |
| 2024/9/3 | METTL3 inhibitor suppresses the progression of prostate cancer via IGFBP3/AKT pathway and synergizes with PARP inhibitor. | Chen X, Wang M, Wang H, Yang J, Li X, Zhang R, Ding X, Hou H, Zhou J, Wu M | Biomed Pharmacother |
| 2024/9/6 | Methyltransferase METTL3 governs the modulation of SH3BGR expression through m6A methylation modification, imparting influence on apoptosis in the context of Down syndrome-associated cardiac development. | Shi W, Chen R, Zhou M, Li Y, Zhang Y, Wang J, Hao B, Liao S | Cell Death Discov |
| 2024/9/6 | Increased m6A RNA methylation and METTL3 expression may contribute to the synovitis progression of rheumatoid arthritis. | Su Y, Wu Z, Liu Y, Liu X, Kang J, Jia J, Zhang L | Exp Cell Res |
| 2024/4/1 | Identification of key differentially methylated genes in regulating muscle development and intramuscular fat deposition in chickens. | Yu B, Cai Z, Liu J, Zhang T, Feng X, Wang C, Li J, Gu Y, Zhang J | Int J Biol Macromol |
| 2024/12/1 | Biogenesis of circRBM33 mediated by N6-methyladenosine and its function in abdominal aortic aneurysm. | Xu Y, Weng X, Qiu J, Wang S | Epigenetics |
| 2024/9/11 | hucMSC-Ex alleviates inflammatory bowel disease in mice by enhancing M2-type macrophage polarization via the METTL3-Slc37a2-YTHDF1 axis. | Xu X, Peng J, Wang N, Ocansey DKW, Zhang X, Mao F | Cell Biol Toxicol |
| 2024/9/17 | The METTL3/TRAP1 axis as a key regulator of 5-fluorouracil chemosensitivity in colorectal cancer. | Kang Q, Hu X, Chen Z, Liang X, Xiang S, Wang Z | Mol Cell Biochem |
| 2024/8/23 | FTO-mediated m (6)A demethylation of ULK1 mRNA promotes autophagy and activation of hepatic stellate cells in liver fibrosis. | Huang T, Zhang C, Ren J, Shuai Q, Li X, Li X, Xie J, Xu J | Acta Biochim Biophys Sin (Shanghai) |
| 2024/10/1 | KIAA1429 promotes the malignancy of oral squamous cell carcinoma by regulating CA9 m6A methylation. | Tu J, Feng X, Cao Q, Guan Y | Cytotechnology |
| 2024/8/6 | METTL3-Regulated lncRNA SNHG7 Drives MNNG-Induced Epithelial-Mesenchymal Transition in Gastric Precancerous Lesions. | Jian J, Feng Y, Wang R, Li C, Zhang L, Ruan Y, Luo B, Liang G, Liu T | Toxics |
| 2024/8/22 | Inhibitor of FTO, Rhein, Restrains the Differentiation of Myoblasts and Delays Skeletal Muscle Regeneration. | Li R, Cao Y, Wu W, Liu H, Xu S | Animals (Basel) |
| 2024/8/17 | Plin4 exacerbates cadmium-decreased testosterone level via inducing ferroptosis in testicular Leydig cells. | Zhang XD, Sun J, Zheng XM, Zhang J, Tan LL, Fan LL, Luo YX, Hu YF, Xu SD, Zhou H, Zhang YF, Li H, Yuan Z, Wei T, Zhu HL, Xu DX, Xiong YW, Wang H | Redox Biol |
| 2024/9/13 | METTL3-driven m6A modification of lncRNA FAM230B suppresses ferroptosis by modulating miR-27a-5p/BTF3 axis in gastric cancer. | Cui Y, Pu M, Gong Y, Li R, Wang X, Ye J, Huang H, Liao D, Yang Y, Yin A, Li J, Deng Y, Tian Z, Pu R | Biochim Biophys Acta Gen Subj |
| 2024/9/13 | The m6A methyltransferase METTL3 modifies Kcnk6 promoting on inflammation associated carcinogenesis is essential for colon homeostasis and defense system through histone lactylation dependent YTHDF2 binding. | Yuan X, Wang Q, Zhao J, Xie H, Pu Z | Int Rev Immunol |
| 2024/12/1 | Chronic social isolation leads to abnormal behavior in male mice through the hippocampal METTL14 mediated epitranscriptomic RNA m6A modifications. | Xu XF, Chen J, Long LH, Zhang AM, Yang JW, Li YJ, Chen L, Zhong XL, Xu Y, Cao WY | J Affect Disord |
| 2024/10/1 | YTHDF1 regulates GID8-mediated glutamine metabolism to promote colorectal cancer progression in m6A-dependent manner. | Han Y, Pu Y, Liu X, Liu Z, Chen Y, Tang L, Zhou J, Song Q, Ji Q | Cancer Lett |
| 2024/8/7 | Unraveling the molecular complexity: Wtap/Ythdf1 and Lcn2 in novel traumatic brain injury secondary injury mechanisms. | Ma C, Gou C, Sun S, Wang J, Wei X, Xing F, Xing N, Yuan J, Wang Z | Cell Biol Toxicol |
| 2024/7/1 | METTL14-mediated upregulation of lncRNA HOTAIR represses PP1?± expression by promoting H3K4me1 demethylation in oxycodone-treated mice. | Liu TC, Li HX, Wan YX, Shi G, Zhao YP, Liu YF, Fan XY | CNS Neurosci Ther |
| 2024/9/1 | METTL3-dependent m6A modification facilitates decreased endometrial decidualization via attenuation of MET in endometriosis. | Xiong W, Jin J, Liu Y | Reproduction |
| 2024/6/21 | Demethylase FTO-mediated m6A modification of SIK1 modulates placental cytotrophoblast syncytialization in type 2 diabetes mellitus. | Ning J, Yan J, Wang S, Cui Z, Xue Y, Juan J, Yang H | iScience |
| 2024/5/15 | METTL5 promotes gastric cancer progression via sphingomyelin metabolism. | Zhang YQ, Li J, Qin Z, Li DM, Ye FZ, Bei SH, Zhang XH, Feng L | World J Gastrointest Oncol |
| 2024/9/1 | WTAP participates in neuronal damage by protein translation of NLRP3 in an m6A-YTHDF1-dependent manner after traumatic brain injury. | Chen Y, Long T, Chen J, Wei H, Meng J, Kang M, Wang J, Zhang X, Xu Q, Zhang C, Xiong K | Int J Surg |
| 2024/8/1 | Triclosan inhibits testosterone biosynthesis in adult rats via inducing m6A methylation-mediated autophagy. | Sang J, Ji Z, Li H, Wang H, Quan H, Yu Y, Yan J, Mao Z, Wang Y, Li L, Ge RS, Lin H | Environ Int |
| 2024/9/20 | FTO-mediated DSP m(6)A demethylation promotes an aggressive subtype of growth hormone-secreting pituitary neuroendocrine tumors. | Zou Y, Bao X, Li D, Ye Z, Xiang R, Yang Y, Zhu Z, Chen Z, Zeng L, Xue C, Zhao H, Yao B, Zhang Q, Yan Z, Deng Z, Cheng J, Yue G, Hu W, Zhao J, Bai R, Zhang Z, Liu A, Zhang J, Zuo Z, Jiang X | Mol Cancer |
| 2024/9/17 | C2H2-zinc-finger transcription factors bind RNA and function in diverse post-transcriptional regulatory processes. | Nabeel-Shah S, Pu S, Burns JD, Braunschweig U, Ahmed N, Burke GL, Lee H, Radovani E, Zhong G, Tang H, Marcon E, Zhang Z, Hughes TR, Blencowe BJ, Greenblatt JF | Mol Cell |
| 2024/9/19 | Bisphenol H exposure disrupts Leydig cell function in adult rats via oxidative stress-mediated m6A modifications: Implications for reproductive toxicity. | Wang S, Lu H, Su M, He J, Tang Y, Ying Y, Chen Z, Zhu Q, Ge RS, Li H, Li X | Ecotoxicol Environ Saf |
| 2024/8/16 | The potential of RNA methylation in the treatment of cardiovascular diseases. | Wang K, Wang Y, Li Y, Fang B, Li B, Cheng W, Wang K, Yang S | iScience |
| 2024/8/19 | Hyperbaric oxygen therapy alleviates intestinal dysfunction following traumatic brain injury via m(6)A regulation. | Yu X, Zhao W, Liu Y, Lv J, Zhong X, Huang P | Int J Med Sci |
| 2024/9/26 | N6-methyladenosine-mediated overexpression of TREM-1 is associated with periodontal disease. | Burra Anand D, Ramamurthy J, Kannan B, Jayaseelan VP, Arumugam P | Odontology |
| 2024/9/27 | The molecular regulated mechanism of METTL3 and FTO in lipid metabolism of Hu sheep. | Chen B, Yuan C, Guo T, Liu J, Yang B, Lu Z | Genomics |
| 2024/9/27 | METTL3-mediated m6A modification of SIRT1 mRNA affects the progression of diabetic cataracts through cellular autophagy and senescence. | Dong S, Zhang J, Fu Y, Tang G, Chen J, Sun D, Qi Y, Zhou N | J Transl Med |
| 2024/9/30 | Methyltransferase METTL3 regulates neuropathic pain through m6A methylation modification of SOCS1. | Wu L, Ning P, Liang Y, Wang T, Chen L, Lu D, Tang H | Neuropharmacology |
| 2024/9/1 | Reserpine, a novel N6-methyladenosine regulator, reverses Lenvatinib resistance in hepatocellular carcinoma. | Zhao L, Ma H, Jiang Y, Li Y, Guo N, Chen Y, Jiang X, Zhao Y, Yang J, Liu Y, Wen K, Wang L, Jian L, Fan X | Phytomedicine |
| 2024/9/11 | Fat Mass- and Obesity-Associated Protein (FTO) Promotes the Proliferation of Goat Skeletal Muscle Satellite Cells by Stabilizing DAG1 mRNA in an IGF2BP1-Related m(6)A Manner. | Yao J, Xu L, Zhao Z, Dai D, Zhan S, Cao J, Guo J, Zhong T, Wang L, Li L, Zhang H | Int J Mol Sci |
| 2024/9/1 | STM2457 Inhibits METTL3-Mediated m6A Modification of miR-30c to Alleviate Spinal Cord Injury by Inducing the ATG5-Mediated Autophagy. | Chen G, Shangguan Z, Ye X, Chen Z, Li J, Liu W | Neurospine |
| 2024/10/4 | N6-methyladenosine modification-tuned lipid metabolism controls skin immune homeostasis via regulating neutrophil chemotaxis. | Cui L, Wu Y, Chen Z, Li B, Cai J, Chang Z, Xiao W, Wang Y, Yang N, Wang Y, Yu Z, Yao L, Ma R, Wang X, Chen Y, Chen Q, Mei H, Lan Z, Yu Y, Chen R, Wu X, Yu Q, Lu J, Yu N, Zhang X, Liu J, Zhang L, Lai Y, Gao S, Gao Y, Guo C, Shi Y | Sci Adv |
| 2024/10/3 | FTO-mediated SMAD2 m6A modification protects cartilage against Osteoarthritis. | Zhou H, Xie Z, Qian Y, Ni W, Cui L, Fang X, Wan S, Zhao X, Qin A, Fan S, Wu Y | Exp Mol Med |
| 2024/10/1 | N6-methyladenosine-mediated upregulation of LNCAROD confers radioresistance in esophageal squamous cell carcinoma through stabilizing PARP1. | Shi X, Zhang X, Huang X, Zhang R, Pan S, Huang S, Wang Y, Ke Y, Guo W, Liu X, Hao Y, Li Y, Zhao X, Sun Y, Li J, Ma H, Zhao X | Clin Transl Med |
| 2024/10/5 | Androgens have therapeutic potential in T2 asthma by mediating METTL3 in bronchial epithelial cells. | Chen Z, Shang Y, Duan W, Zhu L, Ji X, Gong S, Xiang X | Int Immunopharmacol |
| 2024/9/24 | Regulatory role and molecular mechanism of METTL14 in vascular endothelial cell injury in preeclampsia. | Wei H, Liang L, Song C, Tong M, Xu X | Biomol Biomed |
| 2024/10/9 | m6A RNA methyltransferase METTL16 induces Cr(VI) carcinogenesis and lung cancer development through glutamine biosynthesis and GLUL expression. | Xie YX, Wang L, Zhou ZH, Liu WJ, Wang W, Yang JH, He ML, Qiu JG, Jiang BH | J Hazard Mater |
| 2024/10/10 | ALKBH5-Mediated m6A Modification of XBP1 Facilitates NSCLC Progression Through the IL-6-JAK-STAT3 Pathway. | Liang H, Zhang C, Hu M, Hu F, Wang S, Wei W, Hu W | Mol Carcinog |
| 2024/10/11 | m6A modification of mutant huntingtin RNA promotes the biogenesis of pathogenic huntingtin transcripts. | Pupak A, Rodr??guez-Navarro I, Sathasivam K, Singh A, Essmann A, Del Toro D, Gin??s S, Mouro Pinto R, Bates GP, Vang ??rom UA, Mart?? E, Brito V | EMBO Rep |
| 2024/11/1 | RNA methylase RBM15 facilitates malignant progression of colorectal cancer through regulating E2F2 in an m6A modification-dependent manner. | Zhang H, Li Y, Zhou Y, Xu Q, Liao B, Qiu X, Liu J | J Biochem Mol Toxicol |
| 2024/10/18 | ALKBH5 modulation of ferroptosis in recurrent miscarriage: implications in cytotrophoblast dysfunction. | Qin C, Wu J, Wei X, Liu X, Lin Y | PeerJ |
| 2024/10/28 | METTL14-mediated m6A modification upregulated SOCS3 expression alleviates thyroid cancer progression by regulating the JAK2/STAT3 pathway. | Zhou M, Zhang Y, Zhang Q, Tong Y | Mol Cell Probes |
| 2024/10/23 | Regulation of renal ischemia-reperfusion injury and tubular epithelial cell ferroptosis by ppar?? m6a methylation: mechanisms and therapeutic implications. | Liu W, Xiong Z, Fu T, Yang J, Zou J, Wu Y, Kuang L, Wang Q, Li S, Le A | Biol Direct |
| 2024/11/5 | HSYA ameliorates venous thromboembolism by depleting the formation of TLR4/NF-??B pathway-dependent neutrophil extracellular traps. | Li Y, Gu J, Ge J, Kong J, Shang L | Int Immunopharmacol |
| 2024/11/6 | Ythdf2 facilitates precursor miR-378/miR-378-5p maturation to support myogenic differentiation. | Deng K, Su Y, Liu Z, Hu S, Ren C, Wei W, Fan Y, Zhang Y, Wang F | Cell Mol Life Sci |
| 2025/1/1 | METTL3??‘mediated N6??‘methyladenosine modification of MMP9 mRNA promotes colorectal cancer proliferation and migration. | Chen J, Wu H, Zuo T, Wu J, Chen Z | Oncol Rep |
| 2024/11/18 | Transcription and DNA replication collisions lead to large tandem duplications and expose targetable therapeutic vulnerabilities in cancer. | Yang Y, Badura ML, O'Leary PC, Delavan HM, Robinson TM, Egusa EA, Zhong X, Swinderman JT, Li H, Zhang M, Kim M, Ashworth A, Feng FY, Chou J, Yang L | Nat Cancer |
| 2024/11/19 | Transcriptome-wide identification and analysis reveals m6A regulation of metabolic reprogramming in shrimp (Marsupenaeus japonicus) under virus infection. | Sun X, Chen YL, Xin F, Zhang S | BMC Genomics |
| 2024/11/30 | METTL3 and IGF2BP2 coordinately regulate FOSL1 mRNA via m6A modification, suppressing trophoblast invasion and contributing to fetal growth restriction. | Chen R, Wang T, Tong H, Zhang X, Ruan J, Qi H, Liu X, He G | FASEB J |
| 2024/11/1 | RNA m6A methylation regulatory mechanism of resveratrol in premature senescence cells. | Zhang X, Zhu C, Zhang L, Tan L, Cheng W, Li M, Zhang X, Zhang W, Zhang W | Food Sci Nutr |
| 2024/10/26 | Coxsackievirus B3-Induced m6A Modification of RNA Enhances Viral Replication via Suppression of YTHDF-Mediated Stress Granule Formation. | Zhao G, Zhang HM, Chen YT, Shi K, Aghakeshmiri S, Yip F, Luo H, McManus B, Yang D | Microorganisms |
| 2024/11/1 | METTL3 prevents granulosa cells mitophagy by regulating YTHDF2-mediated BNIP3 mRNA degradation due to arsenic exposure. | Zhang T, Niu J, Ren T, Lin H, He M, Sheng Z, Tong Y, Jin B, Wu Y, Pan J, Xiao Z, Guo B, Wang Z, Chen T, Pan W | Ecotoxicol Environ Saf |
| 2024/11/6 | An Investigation of RNA Methylations with Biophysical Approaches in a Cervical Cancer Cell Model. | Sa??lam B, Akku?? O, Ak?§a??z-Alasar A, Ceylan ??, G??ler G, Akg??l B | Cells |
| 2024/11/15 | RNAs m6A modification facilitates UVB-induced photoaging. | Zhang S, Wu M, Lu T, Tian X, Gao L, Yan S, Wang D, Zeng J, Tan L | Heliyon |
| 2024/11/29 | tRNA methyltransferase DNMT2 promotes hepatocellular carcinoma progression and enhances Bortezomib resistance through inhibiting TNFSF10. | Lai J, Chen L, Li Q, Zhao G, Li X, Guo D, Chen Z, Zhang Y, Fan J, Zhao H, Liang J, Tian L, Chen X, Lin J, Chen Q | Cell Signal |
| 2022/11/22 | Sema4D-plexin-B1 signaling in recruiting dental stem cells for vascular stabilization on a microfluidic platform. | Zhang L, Han Y, Chen Q, Dissanayaka WL | Lab Chip |
| 2024/11/29 | m6A demethylase CpALKBH regulates CpZap1 mRNA stability to modulate the development and virulence of chestnut blight fungus. | Zhao L, Wei X, Chen F, Chen B, Li R | mBio |
| 2022/11/22 | Sema4D-plexin-B1 signaling in recruiting dental stem cells for vascular stabilization on a microfluidic platform. | Zhang L, Han Y, Chen Q, Dissanayaka WL | Lab Chip |
| 2024/12/10 | The m6A demethylase ALKBH5 is a novel epigenetic regulator of aortic valve calcification. | Wang Y, He S, Lan L, Yu H, Zhao H, Xie Y, Zhong G, Yuan L, Li K, Hu X, Macrae VE, Fu X, Chen G, Zhu D | Cardiovasc Res |
| 2024/12/7 | METTL3 improves the development of somatic cell nuclear transfer embryos through AURKB and H3S10ph in goats. | Liu Z, Li D, Deng M, Zhou L, Wang J, Liu L, Mao W, Lu H, Xu X, Wang F, Wan Y | Int J Biol Macromol |
| 2024/12/11 | METTL16 controls airway inflammations in smoking-induced COPD via regulating glutamine metabolism. | Jia X, Liu S, Sun C, Zhu M, Yuan Q, Wang M, Xu T, Wang Z, Chen Z, Huang M, Ji N, Zhang M | Ecotoxicol Environ Saf |
| 2024/12/12 | METTL3-mediated m6A modification of EGR1 mRNA promotes T2DM vasculopathy. | Tao M, Shan L, Zhang W, Wei L, Guo M, Fang Z, Zhao J, Gao J | Cell Signal |
| 2024/12/14 | YTHDF2 promotes arsenic-induced malignant phenotypes by degrading PIDD1 mRNA in human keratinocytes. | Zhang Q, Man J, Zhao T, Sun D, Zhang Z | Chem Biol Interact |
| 2025/2/1 | Exosome-Shuttled METTL14 From AML-Derived Mesenchymal Stem Cells Promotes the Proliferation and Radioresistance in AML Cells by Stabilizing ROCK1 Expression via an m6A-IGF2BP3-Dependent Mechanism. | Wang C, Song R, Yuan J, Hou G, Chu AL, Huang Y, Xiao C, Chai T, Sun C, Liu Z | Drug Dev Res |
| 2024/12/18 | 3-Acetyldeoxynivalenol induces pyroptosis in leydig cells via METTL3-mediated N6-methyladenosine modification of NLRP3. | Wang Y, Shi C, Jiao W, Wan X | Ecotoxicol Environ Saf |
| 2024/12/18 | Lipoxin A4 suppresses neutrophil extracellular traps formation through the FPR2-dependent regulation of METTL3 in ischemic stroke. | Wei N, Lu T, Gu J, Cai H | Brain Res Bull |
| 2024/12/23 | RBM15-dependent m6A modification mediates progression of non-small cell lung cancer cells. | Wang M, Qin Y, Ai X, Liu X | Mol Med |
| 2024/12/28 | Knockdown of IGF2BP2 overcomes cisplatin-resistance in lung cancer through downregulating Spon2 gene. | Zhang S, Dou T, Li H, Yu H, Zhang W, Sun L, Yang J, Wang Z, Yang H | Hereditas |
| 2024/12/31 | Targeting the ALKBH5-NLRP3 positive feedback loop alleviates cardiomyocyte pyroptosis after myocardial infarction. | Cui LG, Zhai MM, Yin JJ, Wang ZM, Wang SH, Zhou YJ, Li PP, Wang Y, Xia L, Wang P, Cha XX, Zhang LR, Han SN | Eur J Pharmacol |
| 2025/1/9 | Defining epitranscriptomic hallmarks at the host-parasite interface and their roles in virulence and disease progression in Theileria annulata-infected leukocytes. | Haidar M, Mourier T, Salunke R, Kaushik A, Ben-Rached F, Mfarrej S, Pain A | Biomed J |
| 2025/1/9 | ALKBH5, an m6A demethylase, attenuates tumor growth and inhibits metastasis in papillary thyroid carcinoma. | Zhuang Y, Cai Q, Hu X, Huang H | Sci Rep |
| 2025/1/10 | RNA m6A involves in regulation of oxidative stress and apoptosis may via NF-kB pathway in cadmium-induced lung cells. | Zhang N, Yang J, Zhao Y, Li W, Zhao B, Li R, He Z, Gu S | Cell Death Discov |
| 2025/1/1 | WTAP/IGF2BP3 Mediated m6A Modification of SOD2 mRNA Aggravates the Tumourigenesis of Colorectal Cancer. | Zhou C, Wang M, Du X, Xue L, Zhu X, Li X, Zhao Q | J Biochem Mol Toxicol |
| 2025/1/1 | N6-methyladenosine mediated-NRF2 signaling pathway attenuates cadmium cytotoxicity by inhibiting oxidative damage in bronchial epithelial cells. | Zhang N, Zhao Y, Yang J, Sun Y, Li R, He Z, Gu S | Toxicol Lett |
| 2025/1/13 | m6A Demethyltransferase FTO Attenuates Meniscus Degeneration and Osteoarthritis via Orchestrating Autophagy and Energetic Metabolism. | Jiang Z, Zhang C, Liu R, Zhu Z, Long D, Wen X, Yang Z, Jiang D, Mao G, Liao W, Zhang Z | Adv Sci (Weinh) |
| 2025/3/1 | Triple??‘negative breast cancer cell??‘derived piR??‘31115 promotes the proliferation and migration of endothelial cells via METTL3??‘mediated m6A modification of YAP1. | Du SM, Li N, Xu WJ, Liu K | Oncol Rep |
| 2025/1/18 | Overexpression of FTO alleviates traumatic brain injury induced posttraumatic epilepsy by upregulating NR4A2 expression via m6A demethylation. | Xiao M, Wang X, Xiao E, Ming Q | Funct Integr Genomics |
| 2025/1/21 | Methyltransferase-like 14 promotes ferroptosis in sepsis-induced acute kidney injury via increasing the m6A methylation modification of LPCAT3. | Xu L, Wang QJ, Nie MX, Chen ZF | Mol Genet Genomics |
| 2025/1/22 | FTO Suppresses Proliferation and Induces Apoptosis of T98G Glioblastoma Cells via N6-methyladenosine Modification of GSTO1. | Dong J, Mao J, Wu W, Qian X, Yu Z | Neurochem Res |
| 2025/1/24 | Disrupting of IGF2BP3-stabilized CLDN11 mRNA by TNF-?± increases intestinal permeability in obesity-related severe acute pancreatitis. | Lin L, Lin Y, Guo X, Zhang R, Ling X, Zhang Z, Lin R, Ding Z | Mol Med |
| 2025/1/27 | Epitranscriptome profiles reveal participation of the RNA methyltransferase gene OsMTA1 in rice seed germination and salt stress response. | Li Y, Yin M, Wang J, Zhao X, Xu J, Wang W, Fu B | BMC Plant Biol |
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