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Immundiagnostik:连蛋白Zonulin检测试剂盒

发布者:艾美捷科技    发布时间:2022-04-21     
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Immundiagnostik Zonulin(连蛋白)

 

Zonulin(连蛋白)是一种参与上皮和内皮屏障功能调节的蛋白质,对肠粘膜细胞紧密连接的调节对于维持屏障内环境的平衡至关重要,zonulin是目前唯一已知的细胞间紧密连接的生理调节剂,参与大分子的运输和耐受/免疫反应平衡。当连蛋白与肠的上皮细胞结合时,会诱导信号级联。这种级联分解了肠壁的细胞旁紧密连接。肠壁的紧密连接是允许分子从肠腔转移到血流的两种方式之一,反之亦然。当肠道中的连蛋白水平增加并失去平衡时,这些连接点会打开得更宽,并保持更长时间。这些加宽的入口点允许较大的大分子进入血液或肠腔。通过这些缺口的分子可以增加身体的自然免疫反应,引起炎症和一些自身免疫性疾病。

 

与 Zonulin 水平升高相关的疾病:

  • 1型糖尿病

  • 类风湿关节炎

  • 乳糜泻

  • 肝病

 

Immundiagnostik Zonulin(连蛋白)

 

作为专业的生命科学医药原料供应商,艾美捷科技为您推荐Immundiagnostik荣誉产品,连蛋白Zonulin检测试剂盒:适用于血清(Serum)和粪便(stool)样本!

 

Immundiagnostik Zonulin(连蛋白)

 

产品名称货号样本类型说明书下载备注
IDK? Zonulin (Stool) ELISAK 5600Stool / 粪便点击下载仅科研用途(欧盟CE)
IDK? Zonulin (Stool) ELISAKR5600Stool / 粪便点击下载仅科研用途
IDK? Zonulin (Serum) ELISAK 5601Serum / 血清点击下载仅科研用途

* Immundiagnostik荣誉出品..仅供科研使用,不得用于医疗.

 

Zonulin产品已发表文章:

  • Parker, Jim, Claire O’brien, and Jason Hawrelak. "A narrative review of the role of gastrointestinal dysbiosis in the pathogenesis of polycystic ovary syndrome." Obstetrics & Gynecology Science 65.1 (2022): 14-28.

  • Kleppe, Malin M., et al. "Intestinal barrier integrity in anorexia nervosa (a pilot study)." International Journal of Eating Disorders (2022).

  • Meira de-Faria, Felipe, et al. "Colonic paracellular permeability and circulating zonulin-related proteins." Scandinavian Journal of Gastroenterology 56.4 (2021): 424-431.

  • Tatucu-Babet, Oana A., et al. "Serum zonulin measured by enzyme-linked immunosorbent assay may not be a reliable marker of small intestinal permeability in healthy adults." Nutrition Research 78 (2020): 82-92.

  • Xu, Yiyi, et al. "Inflammatory bowel disease and biomarkers of gut inflammation and permeability in a community with high exposure to perfluoroalkyl substances through drinking water." Environmental Research 181 (2020): 108923.

  • Scherf, Katharina Anne, et al. "Cofactors of wheat-dependent exercise-induced anaphylaxis do not increase highly individual gliadin absorption in healthy volunteers." Clinical and translational allergy 9.1 (2019): 1-12.

  • Kanerva, Sonja. "Assessment of immunological methods for quantification of human zonulin and the effects of intestinal bacteria on zonulin secretion in vitro." (2019).

  • Ajamian, Mary, et al. "Serum zonulin as a marker of intestinal mucosal barrier function: May not be what it seems." PloS one 14.1 (2019): e0210728.

  • Shariatpanahi, Zahra Vahdat, et al. "Effects of early enteral glutamine supplementation on intestinal permeability in critically ill patients." Indian Journal of Critical Care Medicine: Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine 23.8 (2019): 356.

  • Scheffler, Lucas, et al. "Widely used commercial ELISA does not detect precursor of haptoglobin2, but recognizes properdin as a potential second member of the zonulin family." Frontiers in endocrinology 9 (2018): 22.

  • Mokkala, K., et al. "Evaluation of serum zonulin for use as an early predictor for gestational diabetes." Nutrition & diabetes 7.3 (2017): e253-e253.

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