Bcl-2 - associated X protein (Bax) belongs to the Bcl-2 protein family. Bax is a pro-apoptotic Bcl-2 protein containing BH1, BH2 and BH3 domains. Bax accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor bcl2 or its adenovirus homolog e1b 19k protein. Bax induces the release of cytochrome c, activation of casp3, and thereby apoptosis. Bax is expressed in a wide variety of tissues, with highest levels in the testis and ovary. Tumor suppressor protein p53 upregulates the expression of BAX. Bax has been shown to be involved in p53-mediated apoptosis.
序列
该Bax Protein的序列请参考该产品的说明书
来源宿主
E. Coli
溶解建议
该Bax Protein的溶解建议请参考该产品的说明书
保存建议
该Bax Protein的保存建议请参考该产品的说明书
其他
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