TNF-related apoptosis-inducing ligand (TRAIL) is a ligand molecule which induces apoptosis. It is a type II transmembrane protein with homology to other members of the tumor necrosis factor family. In humans, the gene that encodes for TRAIL is located at chromosome 3q26. TRAIL binds to the death receptors, DR4 and DR5. The process of apoptosis is caspase-8-dependent. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues.
序列
该TRAIL Protein的序列请参考该产品的说明书
来源宿主
该TRAIL Protein的来源宿主请参考该产品的说明书
溶解建议
该TRAIL Protein的溶解建议请参考该产品的说明书
保存建议
该TRAIL Protein的保存建议请参考该产品的说明书
其他
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