中文名称

PSMD4 Recombinant Protein (Human)

英文名字

PSMD4 Recombinant Protein (Human)

供应商

Aviva Systems Biology

产品货号

aviva-OPED00127-50UG

产品报价

￥询价/50ug

产品说明书

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产品新闻

背景资料

S5a/Rpn10 is a major ubiquitin binding protein that binds preferentially to polyubiquitin chains. It is found as a non-ATPase subunit of the 19S regulatory complex of the 26S proteasome where it functions as a receptor for proteins destined for proteolytic degradation. In yeast, the homologue of S5a, Rpn10, is required for degradation of a subset of cellular proteins by the proteasome. Unlike other proteasome subunits, S5a exists predominantly as a free protein in the cytosol (i.e. not incorporated into the proteasome), though its precise role in the cytosol has yet to be fully elucidated.
S5a contains two approximately 15 amino acid ubiquitin interacting motifs (UIM) which are responsible for its binding to polyubiquitin chains. In vitro S5a binds predominantly to chains of at least four ubiquitins in length and can act as a substrate for a wide range of ubiquitin E3 ligases, which, it has been suggested, occurs by a novel mechanism involving the association of S5a with growing poly-Ub chains.

序列

该PSMD4 Recombinant Protein (Human)的序列请参考该产品的说明书

来源宿主

E. Coli

溶解建议

该PSMD4 Recombinant Protein (Human)的溶解建议请参考该产品的说明书

保存建议

该PSMD4 Recombinant Protein (Human)的保存建议请参考该产品的说明书

其他

Aviva Systems Biology总部位于加利福尼亚州圣迭戈，在中国北京设有办公室，专注于为研究需求提供多克隆和单克隆抗体、ELISA试剂盒、蛋白质和定制服务。Aviva Systems Biology生产了24,000种经过验证的多克隆抗体，并提供近20,000种ELISA试剂盒，定制实验室服务包括蛋白表达和纯化、抗体开发，以及ELISA的开发、验证和生产。Aviva Systems Biology为与独特物种和靶标相关的研究提供独特工具，研究领域包括转录因子、癌症、心血管、细胞生物学、DNA损伤和修复、表观遗传学、信号转导、细胞分化、干细胞生物学等等。

注意

该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。

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